CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2018	Jun. 30, 2017
Cash flows from operating activities:
Net loss	$ (44,037)	$ (30,657)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation	1,072	1,045
Amortization of intangible assets	10	6
Amortization of investment discount	(146)	219
Equity-based compensation	9,011	7,450
Amortization of debt discount and issuance costs	2,273	0
Loss on disposal of property and equipment	266	5
(Increase) decrease in assets:
Accounts receivable	123	(648)
Inventory	(4,334)	(5,537)
Prepaid expense and other	(444)	(624)
Other current assets	(175)	(313)
Other non-current assets	(78)	0
Increase (decrease) in liabilities:
Accounts payable	206	528
Accrued liabilities	661	392
Increase (Decrease) in Interest Payable, Net	1,105	0
Deferred revenue and income	(935)	43
Deferred compensation	5	0
Net cash used in operating activities	(35,417)	(28,091)
Cash flows from investing activities:
Purchases of equipment	(702)	(1,643)
Purchases of available-for-sale securities	(91,272)	(39,342)
Sales of available-for-sale securities	3,000	6,522
Maturity of available-for-sale securities	38,272	18,449
Net cash used in investing activities	(50,702)	(16,014)
Cash flows from financing activities:
Issuance of common stock net of issuance costs	276	83,854
Exercise of options and warrants	2,757	3,418
Proceeds from issuance of convertible note	171,499	0
Prepayment of forward stock repurchase transaction	(45,069)	0
Payment of debt issuance costs	(4,991)	0
Net cash provided by financing activities	124,472	87,272
Effect of exchange rate on cash:	(56)	198
Increase in cash and cash equivalents	38,297	43,365
Cash and cash equivalents, beginning of period	28,513	19,244
Cash and cash equivalents, end of period	66,810	62,609
Non-cash investing activities:
Transfer of instruments from inventory to property and equipment	$ 1,196	$ 0