Commitments - (Details Narrative) - USD ($)	12 Months Ended
Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Commitments and Contingencies Disclosure [Abstract]
Rent expense	$ 1,100,000	$ 685,000	$ 293,000
Clinical trial master agreement expense	2,100,000	1,600,000	0
Marketing study agreement expense	$ 233,000	$ 66,000	$ 0

Amount of rent expense incurred for leased assets, including but not limited to, furniture and equipment, that is not directly or indirectly associated with the manufacture, sale or creation of a product or product line.

No definition available.

Name:	us-gaap_LeaseAndRentalExpense
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration