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License Agreements and Grants - National Institute of Health Grant (Details) - National Institute of Health Grant - USD ($)
1 Months Ended 12 Months Ended
Feb. 28, 2015
Dec. 31, 2016
Jan. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Research and Development Arrangement, Contract to Perform for Others [Line Items]          
Length of project (years) 5 years        
Total grant funding $ 5,000,000 $ 74,000 $ 818,000 $ 483,000 $ 0