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Commitments - Narrative (Details) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
Commitments and Contingencies Disclosure [Abstract]        
Rent expense $ 280,000 $ 167,000 $ 540,000 $ 282,000
Research and development        
Product Liability Contingency [Line Items]        
Clinical trial expense $ 760,000 $ 178,000 $ 1,424,000 $ 358,000