Consolidated Statements of Operations and Comprehensive Loss - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
Revenues:
Product sales	$ 143	$ 0
Licensing and royalty revenues	20	14
Total revenues	163	14
Costs and expenses:
Research and development	7,353	5,730
Sales, general and administrative	7,437	2,867
Amortization	3	2
Depreciation	542	326
Total costs and expenses	15,335	8,925
Loss from operations	(15,172)	(8,911)
Interest expense and other	0	(1)
Foreign currency exchange gain	44	0
Interest and dividend income	54	15
Total other income	98	14
Net loss	$ (15,074)	$ (8,897)
Basic and diluted net loss per share (dollars per share)	$ (0.29)	$ (0.20)
Weighted average shares outstanding (shares)	51,196	44,650
Other comprehensive loss:
Net unrealized gain on available-for-sale investments	$ 52	$ 5
Foreign currency translation adjustment	(49)	0
Comprehensive loss	$ (15,071)	$ (8,892)