Employee and Consultant Equity-Based Compensation - Equity-Based Compensation Expense and Tax Benefit (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
Equity-based compensation expense	$ 8,388	$ 9,624	$ 3,828
Recognized tax benefit	0	0	0
Research and Development Expense
Equity-based compensation expense	2,479	4,334	1,655
Selling, General and Administrative Expenses [Member]
Equity-based compensation expense	$ 5,909	$ 5,290	$ 2,173