Statements of Operations and Comprehensive Loss (USD $) In Thousands, except Share data, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2014	Sep. 30, 2013	Sep. 30, 2014	Sep. 30, 2013
Revenues:
Licensing and royalty revenues	$ 16	$ 13	$ 43	$ 36
Total revenues	16	13	43	36
Costs and expenses:
Research and development	5,949	2,655	14,074	6,996
Sales, general and administrative	2,625	1,052	8,116	2,916
Amortization	18	19	56	58
Depreciation	251	84	536	191
Total costs and expenses	8,843	3,810	22,782	10,161
Loss from operations	(8,827)	(3,797)	(22,739)	(10,125)
Other expense	(2)	(9)	(5)	(10)
Interest and dividend income	15	9	49	13
Total other income	13	0	44	3
Net loss before income taxes	(8,814)	(3,797)	(22,695)	(10,122)
Benefit from income taxes			527
Net Loss	(8,814)	(3,797)	(22,168)	(10,122)
Net loss per share:
Basic and diluted net loss per share	$ (0.20)	$ (0.10)	$ (0.51)	$ (0.28)
Weighted average shares outstanding	44,583	39,876	43,293	36,083
Other comprehensive loss:
Net loss	(8,814)	(3,797)	(22,168)	(10,122)
Net unrealized gain on available-for-sale investments	(17)	11	(11)	10
Comprehensive loss	$ (8,831)	$ (3,786)	$ (22,179)	$ (10,112)