EXHIBIT 5






                               HART & TRINEN, LLP
                                ATTORNEYS AT LAW
                             1624 Washington Street
                                Denver, CO 80203
William T. Hart, P.C.              ________          Email:  harttrinen@aol.com
Donald T. Trinen                                     Facsimile:  (303) 839-5414
                                 (303) 839-0061
--

Will Hart
                                December 10, 2010


CEL-SCI Corporation
8229 Boone Boulevard, Suite 802
Vienna, Virginia  22182



This letter will constitute an opinion upon the legality of the sale by CEL-SCI
Corporation, a Colorado corporation ("CEL-SCI"), of shares of its common stock
at initial offering prices not to exceed $34,000,000, all as referred to in a
prospectus supplement filed as part of a Registration Statement on Form S-3
(File No. 333-160794) filed by CEL-SCI with the Securities and Exchange
Commission.

We have examined the Articles of Incorporation, the Bylaws, the minutes of the
Board of Directors of CEL-SCI, the applicable laws of the State of Colorado and
a copy of the Registration Statement. In our opinion, CEL-SCI is authorized to
issue the shares of common stock mentioned above and such shares, when issued,
will be lawfully issued and will represent fully paid and non-assessable shares
of CEL-SCI's common stock.


Very truly yours,

HART & TRINEN

/s/ William T. Hart

William T. Hart