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Note 4 - Balance Sheet Components (Tables)
3 Months Ended
Mar. 31, 2026
Notes Tables  
Cash, Cash Equivalent, and Investment [Table Text Block]
  

Amortized

  

Gross Unrealized

  

Estimated

  

Cash and Cash

  

Short-Term

 
  

Cost

  

Gains

  

Losses

  

Fair Value

  

Equivalents

  

Investments

 

March 31, 2026

                        

Cash at banks

 $3,837  $  $  $3,837  $3,837  $ 

Money market funds

  44,121         44,121   44,121    

U.S. Treasury securities

  4,190      (2)  4,188   2,788   1,400 

Commercial paper

  8,881      (5)  8,876      8,876 

Total

 $61,029  $  $(7) $61,022  $50,746  $10,276 
  Amortized  Gross Unrealized  Estimated  Cash and Cash  Short-Term 
  

Cost

  

Gains

  

Losses

  

Fair Value

  

Equivalents

  

Investments

 

December 31, 2025

                        

Cash at banks

 $3,583  $  $  $3,583  $3,583  $ 

Money market funds

  46,164         46,164   46,164    

U.S. Treasury securities

  14,063   1   (4)  14,060   4,067   9,993 

Total

 $63,810  $1  $(4) $63,807  $53,814  $9,993 
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block]
  

March 31, 2026

  

December 31, 2025

 
         

Prepaid clinical and manufacturing expenses

 $10,869  $18,920 

Prepaid insurance

  98   168 

Prepaid rent

  562   539 

Other prepaid

  965   677 

Other current assets

  614   667 

Prepaid expenses and other current assets

 $13,108  $20,971 
Property, Plant, and Equipment [Table Text Block]
  

March 31, 2026

  

December 31, 2025

 
         

Laboratory equipment

 $13,963  $14,005 

Office and computer equipment

  1,158   1,142 

Leasehold improvements

  3,929   3,929 

Construction in progress

  335   158 

Total property and equipment

  19,385   19,234 

Less: accumulated depreciation

  (14,558)  (13,801)

Property and equipment, net

 $4,827  $5,433 
Intangible Asset, Finite-Lived [Table Text Block]
  

March 31, 2026

  

December 31, 2025

 
         

Developed technology

 $5,000  $5,000 

Intellectual property

  80   80 

Total cost

  5,080   5,080 

Less: accumulated amortization

  (2,437)  (2,254)

Intangible assets, net

 $2,643  $2,826 
Intangible Asset, Finite-Lived, and Capitalized Cost, Software to be Sold, Leased, or Marketed, Estimated Amortization Expense [Table Text Block]

Year Ending December 31,

 

Amount

 

2026 (nine months remaining)

 $549 

2027

  731 

2028

  727 

2029

  636 

Total

 $2,643 
Contract with Customer, Contract Asset, Contract Liability, and Receivable [Table Text Block]
  

March 31, 2026

  

December 31, 2025

 
         

Balance at beginning of period

 $68  $65,400 

Revenue recognized

  (45)  (65,513)

Amounts collected or invoiced

     181 

Balance at end of period

 $23  $68 
  

March 31, 2026

  

December 31, 2025

 
         

Balance at beginning of period

 $14,976  $ 

Revenue recognized for collaboration

  (2,815)  (2,108)

Amounts collected or invoiced

     17,084 

Total deferred collaboration revenue

  12,161   14,976 

Current portion

  (11,716)  (12,952)

Long-term portion

 $445  $2,024 
Schedule of Accrued Liabilities [Table Text Block]
  

March 31, 2026

  

December 31, 2025

 
         

Accrued compensation

 $2,259  $4,244 

Accrued clinical and manufacturing expenses

  32,728   42,455 

Accrued professional and consulting services

  718   552 

Other liabilities, current portion

  821   628 

Total

 $36,526  $47,879