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Note 4 - Balance Sheet Components (Tables)
9 Months Ended
Sep. 30, 2025
Notes Tables  
Cash, Cash Equivalent, and Investment [Table Text Block]
  

Amortized

  

Gross Unrealized

  

Estimated

  

Cash and Cash

  

Short-Term

 
  

Cost

  

Gains

  

Losses

  

Fair Value

  

Equivalents

  

Investments

 

September 30, 2025

                        

Cash at banks

 $3,521  $  $  $3,521  $3,521  $ 

Money market funds

  5,727         5,727   5,727    

U.S. Treasury securities

  16,894      (2)  16,892   4,979   11,913 

Commercial paper

  2,653         2,653   2,653    

Total

 $28,795  $  $(2) $28,793  $16,880  $11,913 
  Amortized  Gross Unrealized  Estimated  Cash and Cash  Short-Term 
  

Cost

  

Gains

  

Losses

  

Fair Value

  

Equivalents

  

Investments

 

December 31, 2024

                        

Cash at banks

 $8,740  $  $  $8,740  $8,740  $ 

Money market funds

  16,489         16,489   16,489    

U.S. Treasury securities

  23,802   7   (4)  23,805      23,805 

Commercial paper

  2,688   1      2,689      2,689 

Total

 $51,719  $8  $(4) $51,723  $25,229  $26,494 
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block]
  

September 30, 2025

  

December 31, 2024

 
         

Prepaid clinical and manufacturing expenses

 $750  $1,998 

Prepaid insurance

  394   282 

Prepaid rent

  539   521 

Other prepaid

  861   1,449 

Other current assets

  88   318 

Prepaid expenses and other current assets

 $2,632  $4,568 
Property, Plant and Equipment [Table Text Block]
  

September 30, 2025

  

December 31, 2024

 
         

Laboratory equipment

 $13,897  $13,806 

Office and computer equipment

  1,142   1,140 

Leasehold improvements

  4,000   4,107 

Construction in progress

  11   160 

Total property and equipment

  19,050   19,213 

Less: accumulated depreciation

  (12,986)  (10,508)

Property and equipment, net

 $6,064  $8,705 
Schedule of Finite-Lived Intangible Assets [Table Text Block]
  

September 30, 2025

  

December 31, 2024

 
         

Developed technology

 $5,000  $5,000 

Intellectual property

  80   80 

Total cost

  5,080   5,080 

Less: accumulated amortization

  (2,071)  (1,523)

Intangible assets, net

 $3,009  $3,557 
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]

Year Ending December 31,

 

Amount

 

2025 (three months remaining)

 $184 

2026

  731 

2027

  731 

2028

  727 

2029

  636 

Total

 $3,009 
Contract with Customer, Contract Asset, Contract Liability, and Receivable [Table Text Block]
  

September 30, 2025

 

Balance at December 31, 2024

 $65,400 

Revenue recognized

  (753)

Amounts collected or invoiced

  181 

Balance at September 30, 2025

 $64,828 
Schedule of Accrued Liabilities [Table Text Block]
  

September 30, 2025

  

December 31, 2024

 
         

Accrued compensation

 $3,643  $5,087 

Accrued clinical and manufacturing expenses

  40,216   5,134 

Accrued professional and consulting services

  561   623 

Other liabilities, current portion

  462   534 

Total

 $44,882  $11,378