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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Cash flows from operating activities:    
Net loss $ (30,577,000) $ (40,883,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 4,444,000 4,390,000
Net (accretion) amortization of (discounts) premiums on investments (165,000) (178,000)
Stock-based compensation 4,580,000 6,671,000
Non-cash interest expense related to sale of future royalties 1,669,000 1,414,000
Non-cash revenue related to sale of future royalties (4,521,000) (3,563,000)
Change in operating assets and liabilities:    
Accounts receivable 1,480,000 1,920,000
Unbilled receivable from government contracts (30,573,000) (3,689,000)
Prepaid expenses and other assets 1,534,000 (1,275,000)
Accounts payable 3,648,000 2,083,000
Other accrued liabilities 22,959,000 (108,000)
Net cash used in operating activities (25,544,000) (33,218,000)
Cash flows from investing activities:    
Purchases of property and equipment (27,000) (501,000)
Purchases of investments (9,808,000) (29,187,000)
Proceeds from maturities of investments 30,300,000 15,000,000
Net cash provided by (used in) investing activities 20,465,000 (14,688,000)
Cash flows from financing activities:    
Proceeds from issuance of common stock upon exercise of stock options 3,000 21,000
Shares acquired to settle employee tax withholding liabilities (174,000) (199,000)
Proceeds from issuance of common stock under the employee stock purchase plan 0 312,000
Proceeds from issuance of treasury stock under the employee stock purchase plan 79,000 0
Net cash (used in) provided by financing activities (39,000) 56,436,000
Net increase (decrease) in cash and cash equivalents (5,118,000) 8,530,000
Cash and cash equivalents at beginning of the period 25,229,000 34,755,000
Cash and cash equivalents at end of the period 20,111,000 43,285,000
June 2024 Offering [Member]    
Cash flows from financing activities:    
Net proceeds from issuance of common stock 0 37,555,000
At-the-market Facility [Member]    
Cash flows from financing activities:    
Net proceeds from issuance of common stock 53,000 8,802,000
RA Capital Healthcare Fund 2024 [Member]    
Cash flows from financing activities:    
Net proceeds from issuance of common stock 0 9,945,000
Government Contract [Member]    
Change in operating assets and liabilities:    
Deferred revenue $ (23,000) $ 0