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Note 13 - Income Taxes - Reconciliation of Effective Tax Rate (Details)
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2019
U.S. federal taxes at statutory rate 21.00% 21.00% 21.00%
State taxes (net of federal benefit) 0.10% 0.10%  
Foreign rate differential (1.10%) (0.30%)  
Permanently non-deductible items (1.10%) (1.50%)  
Tax credits 2.70% 3.00%  
Change in valuation allowance (19.70%) (22.00%)  
Prior year true-up (0.10%) (0.20%)  
Other (2.10%) (0.20%)  
Provision for income taxes (0.30%) (0.10%)