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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Revenue from Contract with Customer, Including Assessed Tax $ 0 $ 200 $ 85 $ 818
Operating expenses:        
Research and development 22,466 12,409 60,595 33,219
General and administrative 6,960 5,042 22,939 16,136
Total operating expenses 29,426 17,451 83,534 49,355
Operating loss (29,426) (17,251) (83,449) (48,537)
Other income (expense):        
Interest income, net 458 26 650 58
Non-cash interest expense related to sale of future royalties (325) (337) (988) (1,137)
Foreign exchange loss, net 0 0 (2) (1)
Loss before income taxes (29,293) (17,562) (83,789) (49,617)
Provision for income taxes 16 21 51 89
Net loss $ (29,309) $ (17,583) $ (83,840) $ (49,706)
Net loss per share - basic and diluted (in dollars per share) $ (0.23) $ (0.14) $ (0.66) $ (0.41)
Shares used to compute net loss per share - basic and diluted (in shares) 126,889,718 123,984,141 126,374,424 120,110,780
Comprehensive loss:        
Net loss $ (29,309) $ (17,583) $ (83,840) $ (49,706)
Unrealized (loss) gain on available-for-sale investments, net of tax (109) 6 (444) (3)
Comprehensive loss (29,418) (17,577) (84,284) (49,709)
Customer Service Contracts [Member]        
Revenue from Contract with Customer, Including Assessed Tax 0 0 0 13
Non Cash Royalty Revenue [Member]        
Revenue from Contract with Customer, Including Assessed Tax $ 0 $ 200 $ 85 $ 805