Note 7 - Leases (Details Textual)	3 Months Ended		6 Months Ended		10 Months Ended
	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Jun. 30, 2022 USD ($)	Mar. 31, 2022 USD ($)	Dec. 31, 2021	Jul. 31, 2019
Operating Lease, Weighted Average Discount Rate, Percent	9.27%		9.27%		9.27%
Operating Lease, Weighted Average Remaining Lease Term (Year)	6 years 5 months 8 days		6 years 5 months 8 days		6 years 5 months 8 days
Lessee, Finance Lease, Number of Leases	0		0		0
Short-Term Lease Commitment, Amount	$ 0		$ 0		$ 0
Operating Lease, Payments	$ 933,000	$ 886,000	$ 1,800,000	$ 1,800,000
Right of Use for Equipment with Initial Terms Exceeding One Year [Member]
Lessee, Operating Lease, Number of Right-of-Use Leases	6		6		6
Lease Agreements for Manufacturing Equipment with Initial Terms of One Year or Less [Member]
Lessee, Short-term Lease, Number of Leases	2		2		2
South San Francisco Real Estate [Member]
Lessee, Operating Lease, Renewal Term (Year)							8 years	5 years
Facility in South San Francisco [Member]
Lessee, Operating Lease, Renewal Term (Year)							5 years
Facility in Burlingame, California [Member]
Lessee, Short-term Lease, Number of Leases	2		2		2
Lessee, Operating Lease, Renewal Term (Year)	30 months		30 months		30 months
Lessee, Operating Lease, Number of Renewal Option	2		2		2
Lease for Facility in South San Francisco, California [Member]
Operating Lease, Payments	$ 638,000
Lessee, Operating Lease, Lease Not yet Commenced, Renewal Term (Year)	8 years		8 years		8 years
Lessee, Operating Lease, Lease Not yet Commenced	$ 14,900,000		$ 14,900,000		$ 14,900,000	$ 14,300,000
Lessee, Operating Lease, Lease Not yet Commenced, Minimum Tenant Improvements	$ 7,000,000		$ 7,000,000		7,000,000
Payments for Tenant Improvements					$ 4,000,000.0