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Note 4 - Balance Sheet Components (Tables)
6 Months Ended
Jun. 30, 2022
Notes Tables  
Cash, Cash Equivalents and Investments [Table Text Block]
  

Amortized

  

Gross Unrealized

  

Estimated

  

Cash and Cash

  

Short-Term

  

Long-Term

 
  

Cost

  

Gains

  

Losses

  

Fair Value

  

Equivalents

  

Investments

  

Investments

 

June 30, 2022

                            

Cash at banks

 $21,833  $  $  $21,833  $21,833  $  $ 

Money market funds

  69,635         69,635   69,635       

U.S. Treasury securities

  20,057      (284)  19,773      19,773    

Commercial paper

  12,638      (57)  12,581      10,641   1,940 

Corporate debt securities

  7,732      (68)  7,664      7,664    

Total

 $131,895  $  $(409) $131,486  $91,468  $38,078  $1,940 
  

Amortized

  

Gross Unrealized

  

Estimated

  

Cash and Cash

  

Short-Term

  

Long-Term

 
  

Cost

  

Gains

  

Losses

  

Fair Value

  

Equivalents

  

Investments

  

Investments

 

December 31, 2021

                            

Cash at banks

 $72,767  $  $  $72,767  $72,767  $  $ 

Money market funds

  70,978         70,978   70,978       

U.S. Treasury securities

  25,055      (58)  24,997      12,022   12,975 

Commercial paper

  7,491         7,491      7,491    

Corporate debt securities

  6,480      (16)  6,464      3,229   3,235 

Total

 $182,771  $  $(74) $182,697  $143,745  $22,742  $16,210 
Property, Plant and Equipment [Table Text Block]
  

June 30, 2022

  

December 31, 2021

 
    

Laboratory equipment

 $6,862  $5,057 

Office and computer equipment

  714   481 

Leasehold improvements

  1,063   1,063 

Construction in progress

  2,819   1,305 

Total property and equipment

  11,458   7,906 

Less: accumulated depreciation

  (2,122)  (1,305)

Property and equipment, net

 $9,336  $6,601 
Schedule of Finite-Lived Intangible Assets [Table Text Block]
  

June 30, 2022

  

December 31, 2021

 
    

Developed technology

 $10,600  $10,600 

Intellectual property

  80   80 

Total cost

  10,680   10,680 

Less: accumulated amortization

  (731)  (56)

Intangible assets, net

 $9,949  $10,624 
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]

Year Ending December 31,

 

Amount

 

2022 (six months remaining)

 $675 

2023

  1,350 

2024

  1,350 

2025

  1,350 

2026

  1,350 

Thereafter

  3,874 

Total

 $9,949 
Schedule of Accrued Liabilities [Table Text Block]
  

June 30, 2022

  

December 31, 2021

 
         

Accrued compensation

 $3,200  $2,786 

Accrued clinical and manufacturing expenses

  913   986 

Accrued professional and consulting services

  907   556 

Accrued litigation settlement

  2,000    

Other liabilities, current portion

  1,420   736 

Total

 $8,440  $5,064