Note 4 - Balance Sheet Components (Tables)

3 Months Ended

Mar. 31, 2022

Notes Tables

Cash, Cash Equivalents and Investments [Table Text Block]

	Amortized		Gross Unrealized					Estimated		Cash and Cash		Short-Term		Long-Term
	Cost		Gains		Losses			Fair Value		Equivalents		Investments		Investments
March 31, 2022
Cash at banks	$	47,310	$	—	$	—		$	47,310	$	47,310	$	—	$	—
Money market funds		76,094		—		—			76,094		76,094		—		—
U.S. Treasury securities		20,576		—		(257	)		20,319		—		10,970		9,349
Commercial paper		6,882		—		—			6,882		—		6,882		—
Corporate debt securities		6,454		—		(52	)		6,402		—		6,402		—
Total	$	157,316	$	—	$	(309	)	$	157,007	$	123,404	$	24,254	$	9,349

	Amortized		Gross Unrealized					Estimated		Cash and Cash		Short-Term		Long-Term
	Cost		Gains		Losses			Fair Value		Equivalents		Investments		Investments
December 31, 2021
Cash at banks	$	72,767	$	—	$	—		$	72,767	$	72,767	$	—	$	—
Money market funds		70,978		—		—			70,978		70,978		—		—
U.S. Treasury securities		25,055		—		(58	)		24,997		—		12,022		12,975
Commercial paper		7,491		—		—			7,491		—		7,491		—
Corporate debt securities		6,480		—		(16	)		6,464		—		3,229		3,235
Total	$	182,771	$	—	$	(74	)	$	182,697	$	143,745	$	22,742	$	16,210

Property, Plant and Equipment [Table Text Block]

	March 31, 2022			December 31, 2021
Laboratory equipment	$	5,537		$	5,057
Office and computer equipment		526			481
Leasehold improvements		1,063			1,063
Construction in progress		2,178			1,305
Total property and equipment		9,304			7,906
Less: accumulated depreciation		(1,675	)		(1,305	)
Property and equipment, net	$	7,629		$	6,601

Schedule of Finite-Lived Intangible Assets [Table Text Block]

	March 31, 2022			December 31, 2021
Developed technology	$	10,600		$	10,600
Intellectual property		80			80
Total cost		10,680			10,680
Less: accumulated amortization		(394	)		(56	)
Intangible assets, net	$	10,286		$	10,624

Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]

Year Ending December 31,	Amount
2022 (nine months remaining)	$	1,012
2023		1,350
2024		1,350
2025		1,350
2026		1,350
Thereafter		3,874
Total	$	10,286

Schedule of Accrued Liabilities [Table Text Block]

	March 31, 2022		December 31, 2021
Accrued compensation	$	1,907	$	2,786
Accrued clinical and manufacturing expenses		848		986
Accrued professional and consulting services		1,175		556
Other liabilities, current portion		1,173		736
Total	$	5,103	$	5,064