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Note 4 - Balance Sheet Components (Tables)
9 Months Ended
Sep. 30, 2021
Notes Tables  
Cash, Cash Equivalents and Investments [Table Text Block]
  

Amortized

  

Gross Unrealized

  

Estimated

  

Cash and Cash

  

Short-Term

  

Long-Term

 
  

Cost

  

Gains

  

Losses

  

Fair Value

  

Equivalents

  

Investments

  

Investments

 

September 30, 2021

                            

Cash at banks

 $93,955  $  $  $93,955  $93,955  $  $ 

Money market funds

  73,276         73,276   73,276       

U.S. Treasury securities

  23,025      (3)  23,022      9,997   13,025 

Commercial paper

  7,192         7,192      7,192    

Corporate debt securities

  6,506         6,506      3,249   3,257 

Total

 $203,954  $  $(3) $203,951  $167,231  $20,438  $16,282 
  

Amortized

  

Gross Unrealized

  

Estimated

  

Cash and Cash

  

Short-Term

  

Long-Term

 
  

Cost

  

Gains

  

Losses

  

Fair Value

  

Equivalents

  

Investments

  

Investments

 

December 31, 2020

                            

Cash at banks

 $66,865  $  $  $66,865  $66,865  $  $ 

Money market funds

  60,005         60,005   60,005       

Total

 $126,870  $  $  $126,870  $126,870  $  $ 
Property, Plant and Equipment [Table Text Block]
  

September 30, 2021

  

December 31, 2020

 
    

Laboratory equipment

 $3,389  $1,759 

Office and computer equipment

  382   294 

Leasehold improvements

  1,057    

Construction in progress

  1,578    

Total property and equipment

  6,406   2,053 

Less: accumulated depreciation

  (979)  (573)

Property and equipment, net

 $5,427  $1,480 
Lessee, Operating Lease, Right-of-Use Assets [Table Text Block]
  

September 30, 2021

  

December 31, 2020

 
    

Facilities

 $12,237  $6,836 

Office equipment

     2 

Right-of-use assets, net

 $12,237  $6,838 
Schedule of Finite-Lived Intangible Assets [Table Text Block]
  

September 30, 2021

  

December 31, 2020

 
    

Developed technology

 $20,300  $20,300 

Intellectual property

  80   80 

Total cost

  20,380   20,380 

Less: accumulated amortization

  (6,318)  (5,019)

Intangible assets, net

 $14,062  $15,361 
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]

Year Ending December 31,

 

Amount

 

2021 (three months remaining)

 $433 

2022

  1,731 

2023

  1,732 

2024

  1,732 

2025

  1,731 

Thereafter

  6,703 

Total

 $14,062 
Schedule of Accrued Liabilities [Table Text Block]
  

September 30, 2021

  

December 31, 2020

 
         

Accrued compensation

 $2,084  $1,618 

Accrued clinical and manufacturing expenses

  725   1,772 

Accrued professional and consulting services

  782   777 

Other liabilities, current portion

  796   632 

Total

 $4,387  $4,799