X0306 4 2021-08-10 0000072444 Vaxart, Inc. VXRT 0001530193 Echerd Margaret C/O VAXART, INC. 170 HARBOR WAY, SUITE 300 SOUTH SAN FRANCISCO CA 94080 1 SVP, Principal Accntng Officer Common Stock 2021-08-10 4 M 0 333 5.17 A 333 D Common Stock 2021-08-10 4 M 0 1468 0.77 A 1801 D Common Stock 2021-08-10 4 S 0 1801 10 D 0 D Stock Option (right to buy) 5.17 2021-08-10 4 M 0 333 0 D 2028-05-24 Common stock 333 2667 D Stock Option (right to buy) 0.77 2021-08-10 4 M 0 1468 0 D 2029-06-11 Common stock 1468 30819 D The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 1, 2021. The stock option vests over a four-year period, with 25% of the shares subject to the stock option vesting on the first anniversary of the vesting commencement date of April 9, 2018, and the remaining shares in 36 equal monthly installments thereafter. The stock option vests over a four-year period, with 25% of the shares subject to the stock option vesting on the first anniversary of the vesting commencement date of May 10, 2019, and the remaining shares in 36 equal monthly installments thereafter. /s/ Margaret Echerd 2021-08-11