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Condensed Consolidated Statements of Cash Flows - USD ($)
6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Cash flows from operating activities:    
Net loss $ (32,123,000) $ (10,274,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 1,989,000 1,193,000
Accretion of premium on investments 24,000 0
Stock-based compensation 3,855,000 2,956,000
Non-cash interest expense related to sale of future royalties 800,000 937,000
Non-cash revenue related to sale of future royalties (802,000) (2,800,000)
Change in operating assets and liabilities:    
Accounts receivable 227,000 3,392,000
Prepaid expenses and other assets (3,473,000) (657,000)
Accounts payable 1,348,000 148,000
Other accrued liabilities (1,596,000) 1,376,000
Net cash used in operating activities (29,751,000) (3,729,000)
Cash flows from investing activities:    
Purchase of property and equipment (2,818,000) (13,000)
Proceeds from sale of equipment 0 3,000
Purchases of investments (34,890,000) 0
Proceeds from maturities of investments 1,200,000 0
Net cash used in investing activities (36,508,000) (10,000)
Cash flows from financing activities:    
Proceeds from issuance of common stock upon exercise of common stock warrants 1,849,000 24,658,000
Proceeds from issuance of common stock upon exercise of stock options 892,000 116,000
Disgorgement of short-swing profits, net of costs 0 652,000
Net cash provided by financing activities 104,655,000 34,601,000
Net increase in cash and cash equivalents 38,396,000 30,862,000
Cash and cash equivalents at beginning of the period 126,870,000 13,526,000
Cash and cash equivalents at end of the period 165,266,000 44,388,000
Supplemental disclosure of non-cash financing activity:    
Issuance of warrants to placement agent’s representatives 0 453,000
Operating lease liabilities arising from obtaining right-of-use assets 56,000 0
Lease-related assets and liabilities derecognized on early termination and modification of leases 158,000 0
Acquisition of property and equipment included in accounts payable and accrued expenses 314,000 170,000
Registered Direct Offering [Member]    
Cash flows from financing activities:    
Net proceeds from issuance of common stock 0 9,175,000
ATM Program [Member]    
Cash flows from financing activities:    
Net proceeds from issuance of common stock $ 101,914,000 $ 0