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Note 1 - Organization and Basis of Presentation (Details Textual)
$ / shares in Units, $ in Millions
3 Months Ended 6 Months Ended
Oct. 13, 2020
USD ($)
Mar. 31, 2021
USD ($)
$ / shares
shares
Dec. 31, 2020
USD ($)
$ / shares
shares
Mar. 31, 2021
USD ($)
$ / shares
shares
Jun. 08, 2020
$ / shares
shares
Jun. 07, 2020
shares
Apr. 11, 2019
$ / shares
Common Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares   $ 0.0001 $ 0.0001 $ 0.0001 $ 0.0001    
Common Stock, Shares Authorized (in shares) | shares   150,000,000 150,000,000 150,000,000 150,000,000 100,000,000  
Number of Operating Segments   1          
Open Market Sale Agreement [Member]              
Open Market Sale Agreement, Maximum Aggregate Offering Price $ 250.0            
Payments of Stock Issuance Costs $ 0.3            
Open Market Sale Agreement, Sales Commission, Percentage 4.50%            
Stock Issued During Period, Shares, New Issues (in shares) | shares   6,654,367 692,651 7,347,018      
Proceeds from Issuance of Common Stock   $ 68.9 $ 5.5 $ 74.4      
Proceeds from Issuance of Common Stock, Net   $ 65.7 $ 4.9 $ 70.6      
Warrants in Connection With the April 2019 Offering [Member]              
Pre-funded Warrant, Accompanying Warrant, Amount Paid Per Share (in dollars per share) | $ / shares             $ 0.10