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Note 5 - Balance Sheet Components
12 Months Ended
Dec. 31, 2020
Notes to Financial Statements  
Supplemental Balance Sheet Disclosures [Text Block]
NOTE 
5.
  Balance Sheet Components
 
(a)
    
Cash and Cash Equivalents
 
Cash and cash equivalents comprises the following (in thousands):
 
   
December 31, 2020
   
December 31, 2019
 
       
Cash at banks
  $
66,865
    $
13,511
 
Money market funds
   
60,005
     
15
 
Cash and cash equivalents
  $
126,870
    $
13,526
 
 
(b)
    
Accounts Receivable
 
Accounts receivable comprises the following (in thousands):
 
   
December 31, 2020
   
December 31, 2019
 
       
Royalties receivable
  $
334
    $
3,438
 
Customer service contracts – billed
   
     
181
 
Accounts receivable
  $
334
    $
3,619
 
 
(c)
    
Property and Equipment, Net
 
Property and equipment, net consists of the following (in thousands):
 
   
December 31, 2020
   
December 31, 2019
 
       
Laboratory equipment
  $
1,759
    $
537
 
Office and computer equipment
   
294
     
132
 
Total property and equipment
   
2,053
     
669
 
Less: accumulated depreciation
   
(573
)    
(459
)
Property and equipment, net
  $
1,480
    $
210
 
 
Depreciation expense was
$114,000,
$504,000
and
$476,000
for the years ended
December 31, 2020,
2019
and
2018
, respectively. Property and equipment and leasehold improvements at
one
of the Company's leased premises in California that were used in the Company's manufacturing operations (see Note
15
) were assessed as impaired as of
December 31, 2019,
and accordingly an impairment charge of
$1,152,000
 was recorded as a component of restructuring costs within operating expenses. Leasehold improvements and furniture at the Company's leased premises in Georgia, which has been subleased, commencing in
November 2018,
for less than the rental that the Company is obligated to pay (see Note
8
), were assessed as impaired as of
September 30, 2018,
and accordingly an impairment charge of
$106,000
was recorded as a component of costs of exit from leased premises within operating expenses.
 
(d)
     Right-of-Use
 Assets, Net
 
Right-of-use assets consist of the following (in thousands):
 
   
December 31, 2020
   
December 31, 2019
 
                 
Facilities
  $
6,836
    $
1,985
 
Office equipment
   
2
     
5
 
Right-of-use assets, net
  $
6,838
    $
1,990
 
 
The right of use of
one
of the Company's leased premises in California used in the Company's manufacturing operations (see Note
15
) was assessed as impaired as of
December 31, 2019,
and accordingly an impairment charge of
$120,000
 was recorded as a component of restructuring costs within operating expenses.
 
(e)
    
Intangible Assets, Net
 
Intangible assets comprise developed technology, intellectual property and, until it was considered fully impaired, in-process research and development. Intangible assets are carried at cost less accumulated amortization. Amortization is computed using the straight-line method over useful lives ranging from
1.3
to
11.75
years for developed technology and
20
 years for intellectual property. As of
December 31, 2020,
developed technology and intellectual property had remaining lives of
8.9
and
7.0
years, respectively. Intangible assets consist of the following (in thousands):
 
   
December 31, 2020
   
December 31, 2019
 
       
Purchased technology
  $
20,300
    $
22,100
 
Intellectual property
   
80
     
80
 
Total cost
   
20,380
     
22,180
 
Less accumulated amortization
   
(5,019
)    
(5,087
)
Intangible assets, net
  $
15,361
    $
17,093
 
 
Intangible asset amortization expense was
$1,732,000,
$2,320,000
and
$2,727,000
for the years ended 
December 31, 2020,
2019
and
2018
, respectively. Following the results of Phase
2
trials in
June 2018,
the in-process research and development was assessed as fully impaired in the
three
months ended
June 
30,
2018,
with the
$1.6
million acquired in the Merger (see Note
3
) being charged to operating expenses.
 
As of
December 31, 2020
, the estimated future amortization expense by year is as follows (in thousands):
 
Year Ending December 31,
 
Amount
 
2021
  $
1,732
 
2022
   
1,731
 
2023
   
1,732
 
2024
   
1,732
 
2025
   
1,731
 
Thereafter
   
6,703
 
Total
  $
15,361
 
 
(f)
    
Other Accrued Liabilities
 
Other accrued liabilities consist of the following (in thousands):
 
   
December 31, 2020
   
December 31, 2019
 
       
Accrued compensation
  $
1,618
    $
903
 
Accrued clinical and manufacturing expenses
   
1,772
     
3,228
 
Accrued professional and consulting services
   
777
     
2
 
Reserve for return of royalties
   
     
178
 
Other
   
632
     
254
 
Total
  $
4,799
    $
4,565