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Note 11 - Equity Incentive Plans (Tables)
9 Months Ended
Sep. 30, 2020
Notes Tables  
Share-based Payment Arrangement, Option, Activity [Table Text Block]
     
 
 
   
 
 
 
Weighted
 
   
Shares
   
Number of
   
Average
 
   
Available
   
Options
   
Exercise
 
   
For Grant
   
Outstanding
   
Price
 
                         
Balance at January 1, 2020
   
295,180
     
1,811,652
    $
2.74
 
2019 Plan Amendment    
6,400,000
     
    $
 
PRSUs granted, net of tax forfeitures    
(278,535
)    
    $
 
Granted    
(4,957,800
)    
4,957,800
    $
2.10
 
Exercised    
     
(305,179
)   $
1.32
 
Forfeited    
85,910
     
(85,992
)   $
0.39
 
Canceled
   
9,573
     
(57,751
)   $
10.57
 
                         
Balance at September 30, 2020
   
1,554,328
     
6,320,530
    $
2.27
 
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
   
Nine Months Ended September 30,
 
   
2020
   
2019
 
                 
Risk-free interest rate
   
0.40%
-
0.88%
     
1.89%
-
2.31%
 
Expected term
 
5.22 - 10.00 Years
   
5.39 - 6.08 Years
 
Expected volatility
   
94%
-
108%
     
83%
-
85%
 
Dividend yield
   
%    
%
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
   
Three Months Ended September 30,
   
Nine Months Ended September 30,
 
   
2020
   
2019
   
2020
   
2019
 
   
(in thousands)
   
(in thousands)
 
Research and development
  $
268
    $
63
    $
1,405
    $
222
 
General and administrative
   
647
     
83
     
2,466
     
268
 
Total stock-based compensation
  $
915
    $
146
    $
3,871
    $
490