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Note 10 - Stockholders' Equity (Tables)
9 Months Ended
Sep. 30, 2020
Notes Tables  
Schedule of Common Stock Reserved for Issuance [Table Text Block]
   
September 30, 2020
   
December 31, 2019
 
                 
Options issued and outstanding
   
6,320,530
     
1,811,652
 
PRSUs issued and outstanding    
411,000
     
 
Available for future grants of equity awards
   
1,554,328
     
295,180
 
Common stock warrants
   
1,244,974
     
43,370,162
 
Total
   
9,530,832
     
45,476,994
 
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]
Securities into which warrants are convertible
 
Warrants outstanding
   
Exercise Price
 
Expiration Date
                   
Common Stock
   
5,000
    $
0.30
 
September 2024
Common Stock
   
224,797
    $
0.375
 
September 2024
Common Stock
   
225,966
    $
1.10
 
April 2024
Common Stock
   
111,931
    $
1.375
 
April 2024
Common Stock
   
316,584
    $
2.50
 
March 2025
Common Stock
   
269,496
    $
3.125
 
February 2025
Common Stock
   
80,286
    $
3.125
 
March 2024
Common Stock
   
10,914
    $
22.99
 
December 2026
Total
   
1,244,974