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Note 13 - Equity Incentive Plans - Total Stock-based Compensation Recognized for Options (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Stock-based compensation $ 627 $ 539
Research and Development Expense [Member]    
Stock-based compensation 253 254
General and Administrative Expense [Member]    
Stock-based compensation $ 374 $ 285