Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Revenue:
Revenue from Contract with Customer, Including Assessed Tax	$ 9,862	$ 4,159
Operating expenses:
Research and development	14,540	17,275
General and administrative	6,187	6,681
Impairment of intangible assets		1,600
Costs of exit from leased premises		359
Restructuring costs	4,920
Total operating expenses	25,647	25,915
Operating loss	(15,785)	(21,756)
Other income and (expenses):
Bargain purchase gain		6,760
Interest income	149	58
Interest expense	(315)	(821)
Non-cash interest expense related to the sale of future royalties	(2,073)	(1,859)
Gain (loss) on sale of equipment	1	(11)
Loss on revaluation of financial instruments		(3)
Loss on debt extinguishment	(100)
Foreign exchange loss, net	(32)	(266)
Total other income and (expenses)	(2,370)	3,858
Net loss before provision for income taxes	(18,155)	(17,898)
Provision for income taxes	490	109
Net loss	(18,645)	(18,007)
Series B and C preferred dividend		(339)
Net comprehensive loss attributable to common stockholders	$ (18,645)	$ (18,346)
Net loss per share – basic and diluted (in dollars per share)	$ (0.86)	$ (2.90)
Shares used to compute net loss per share – basic and diluted (in shares)	21,569,523	6,316,065
Customer Service Contracts [Member]
Revenue:
Revenue from Contract with Customer, Including Assessed Tax	$ 406
Government Contract [Member]
Revenue:
Revenue from Contract with Customer, Including Assessed Tax	(20)	1,344
Royalty [Member]
Revenue:
Revenue from Contract with Customer, Including Assessed Tax	4,446	1,340
Non Cash Royalty Revenue [Member]
Revenue:
Revenue from Contract with Customer, Including Assessed Tax	$ 5,030	$ 1,475