Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)	3 Months Ended		9 Months Ended
	Sep. 30, 2019	Sep. 30, 2018	Sep. 30, 2019	Sep. 30, 2018
Revenue:
Revenue from Contract with Customer, Including Assessed Tax	$ 454,000	$ 281,000	$ 5,946,000	$ 2,392,000
Operating expenses:
Research and development	3,713,000	4,381,000	11,249,000	12,801,000
General and administrative	1,455,000	1,674,000	4,856,000	5,455,000
Impairment of intangible assets				1,600,000
Impairment of property and equipment		106,000		106,000
Total operating expenses	5,168,000	6,161,000	16,105,000	19,962,000
Operating loss	(4,714,000)	(5,880,000)	(10,159,000)	(17,570,000)
Other income and (expenses):
Bargain purchase gain				6,660,000
Interest income	58,000	11,000	97,000	52,000
Interest expense	(84,000)	(129,000)	(288,000)	(702,000)
Non-cash interest expense related to sale of future royalties	(500,000)	(532,000)	(1,560,000)	(1,298,000)
Loss on revaluation of financial instruments				(3,000)
Foreign exchange loss, net	11,000	(18,000)	(32,000)	(215,000)
Total other income and (expenses)	(515,000)	(668,000)	(1,783,000)	4,494,000
Net loss before income taxes	(5,229,000)	(6,548,000)	(11,942,000)	(13,076,000)
Provision for income taxes	31,000		294,000	29,000
Net loss	(5,260,000)	(6,548,000)	(12,236,000)	(13,105,000)
Series B and C preferred dividend				(339,000)
Net comprehensive loss attributable to common stockholders	$ (5,260,000)	$ (6,548,000)	$ (12,236,000)	$ (13,444,000)
Net loss per share - basic and diluted (in dollars per share)	$ (0.32)	$ (0.92)	$ (0.96)	$ (2.23)
Shares used to compute net loss per share - basic and diluted (in shares)	16,249,032	7,141,189	12,748,665	6,038,001
Customer Service Contracts [Member]
Revenue:
Revenue from Contract with Customer, Including Assessed Tax	$ 94,000		$ 94,000
Government Contract [Member]
Revenue:
Revenue from Contract with Customer, Including Assessed Tax		194,000		1,324,000
Royalty [Member]
Revenue:
Revenue from Contract with Customer, Including Assessed Tax	8,000	87,000	3,736,000	1,050,000
Non Cash Royalty Revenue [Member]
Revenue:
Revenue from Contract with Customer, Including Assessed Tax	$ 352,000		$ 2,116,000	$ 18,000