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Note 12 - Net Loss Per Share Attributable to Common Stockholders (Tables)
9 Months Ended
Sep. 30, 2019
Notes Tables  
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
   
Three Months Ended September 30,
   
Nine Months Ended September 30,
 
   
2019
   
2018
   
2019
   
2018
 
                                 
Net loss
  $
(5,260
)   $
(6,548
)   $
(12,236
)   $
(13,105
)
                                 
Series B and C preferred dividend
   
     
     
     
(339
)
                                 
Net loss attributable to common stockholders – diluted calculation
  $
(5,260
)   $
(6,548
)   $
(12,236
)   $
(13,444
)
                                 
Shares used to compute net loss per share – basic and diluted
   
16,249,032
     
7,141,189
     
12,748,665
     
6,038,001
 
                                 
Net loss per share – basic and diluted
  $
(0.32
)   $
(0.92
)   $
(0.96
)   $
(2.23
)
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
   
Three Months Ended September 30,
   
Nine Months Ended September 30,
 
   
2019
   
2018
   
2019
   
2018
 
                                 
Options to purchase common stock
   
1,965,910
     
978,495
     
1,466,495
     
802,885
 
                                 
Warrants to purchase common stock
   
13,064,514
     
10,914
     
8,340,589
     
9,195
 
                                 
Warrant to purchase convertible preferred stock
   
     
     
     
1,191
 
                                 
Series B and C convertible preferred stock outstanding, including cumulative dividends
   
     
     
     
285,797
 
                                 
Series A convertible preferred stock outstanding
   
     
     
     
16,391
 
                                 
Convertible promissory notes, related party (as converted)
   
     
     
     
247,557
 
                                 
Total potentially dilutive securities excluded from denominator of the diluted earnings per share computation
   
15,030,424
     
989,409
     
9,807,084
     
1,363,016