CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY - USD ($) shares in Thousands, $ in Thousands	Total	Issuance of common stock to RPI Finance Trust	Common Stock	Common Stock IPO	Common Stock Issuance of common stock to RPI Finance Trust	Capital Contributed in Excess of Par	Capital Contributed in Excess of Par IPO	Capital Contributed in Excess of Par Issuance of common stock to RPI Finance Trust	Treasury Stock	Accumulated Deficit	Accumulated Other Comprehensive Income (Loss)	Noncontrolling Interest	Convertible Preferred Stock
Beginning balance (in shares) at Dec. 31, 2017			161,303										0
Beginning Balance at Dec. 31, 2017	$ 16,450		$ 1,613			$ 659,467			$ (458)	$ (642,973)	$ (401)	$ (798)	$ 0
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Reclassification of warrant liability to equity, net	139,752					139,752
Adjustment of noncontrolling interest	0					3,577						(3,577)
Exercise of stock options (in shares)			622
Exercise of stock options, net	1,726		$ 6			2,354			(634)
Exercise of common stock warrants (in shares)			7,500
Exercise of common stock warrants	28,125		$ 75			28,050
Issuance of common stock (in shares)				13,225	4,373
Issuance of common stock	299,467	$ 67,784		$ 132	$ 44		$ 299,335	$ 67,740
Stock-based compensation (in shares)			314
Stock-based compensation	4,419		$ 3			4,416
Conversion of RSU's for tax withholding payments (in shares)			(194)
Conversion of RSU's for tax withholding payments	(1,668)		$ (2)			(1,666)
Other comprehensive income (loss)	67										67
Net loss	(216,807)									(216,744)		(63)
Ending balance (in shares) at Sep. 30, 2018			187,143										0
Ending Balance at Sep. 30, 2018	339,315		$ 1,871			1,203,025			(1,092)	(859,717)	(334)	(4,438)	$ 0
Beginning balance (in shares) at Jun. 30, 2018			186,801										0
Beginning Balance at Jun. 30, 2018	399,686		$ 1,868			1,194,998			(458)	(795,548)	(353)	(821)	$ 0
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Reclassification of warrant liability to equity, net	1,776					1,776
Adjustment of noncontrolling interest	0					3,577						(3,577)
Exercise of stock options (in shares)			219
Exercise of stock options, net	130		$ 2			762			(634)
Exercise of common stock warrants (in shares)			100
Exercise of common stock warrants	375		$ 1			374
Stock-based compensation (in shares)			30
Stock-based compensation	1,734					1,734
Conversion of RSU's for tax withholding payments (in shares)			(7)
Conversion of RSU's for tax withholding payments	(196)		$ 0			(196)
Other comprehensive income (loss)	19										19
Net loss	(64,209)									(64,169)		(40)
Ending balance (in shares) at Sep. 30, 2018			187,143										0
Ending Balance at Sep. 30, 2018	339,315		$ 1,871			1,203,025			(1,092)	(859,717)	(334)	(4,438)	$ 0
Beginning balance (in shares) at Dec. 31, 2018			190,446										0
Beginning Balance at Dec. 31, 2018	265,849		$ 1,905			1,219,237			(824)	(953,216)	(351)	(902)	$ 0
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Exercise of stock options (in shares)			1,164
Exercise of stock options, net	2,281		$ 11			3,541			(1,271)
Issuance of common stock (in shares)			371
Issuance of common stock	5,829		$ 4			5,825
Stock-based compensation (in shares)			15
Stock-based compensation	7,327		$ 0			7,327
Other comprehensive income (loss)	(250)										(250)
Net loss	(257,680)									(257,582)		(98)
Ending balance (in shares) at Sep. 30, 2019			191,996										0
Ending Balance at Sep. 30, 2019	23,356		$ 1,920			1,235,930			(2,095)	(1,210,798)	(601)	(1,000)	$ 0
Beginning balance (in shares) at Jun. 30, 2019			191,972										0
Beginning Balance at Jun. 30, 2019	114,560		$ 1,920			1,232,575			(2,095)	(1,116,506)	(365)	(969)	$ 0
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Exercise of stock options (in shares)			24
Exercise of stock options, net	175		$ 0			175			0
Stock-based compensation (in shares)			0
Stock-based compensation	3,180		$ 0			3,180
Other comprehensive income (loss)	(236)										(236)
Net loss	(94,323)									(94,292)		(31)
Ending balance (in shares) at Sep. 30, 2019			191,996										0
Ending Balance at Sep. 30, 2019	$ 23,356		$ 1,920			$ 1,235,930			$ (2,095)	$ (1,210,798)	$ (601)	$ (1,000)	$ 0