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  <xsd:element id="immu_RoyaltyPurchaseAgreementArrangementsConsideration" name="RoyaltyPurchaseAgreementArrangementsConsideration" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="immu_RoyaltyPurchaseArrangementAnnualSalesLimitMaximum" name="RoyaltyPurchaseArrangementAnnualSalesLimitMaximum" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="immu_RoyaltyPurchaseArrangementExcessGlobalAnnualSalesLimitMinimum" name="RoyaltyPurchaseArrangementExcessGlobalAnnualSalesLimitMinimum" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="immu_RoyaltyPurchaseArrangementRoyaltyRateasPercentageofExcessofGlobalAnnualSalesThresholdLimit" name="RoyaltyPurchaseArrangementRoyaltyRateasPercentageofExcessofGlobalAnnualSalesThresholdLimit" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="immu_RoyaltyPurchaseArrangementRoyaltyRateasPercentageofNetSales" name="RoyaltyPurchaseArrangementRoyaltyRateasPercentageofNetSales" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="immu_RpiFinanceTrustMember" name="RpiFinanceTrustMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="immu_ScheduleOfFairValueMeasurementsWarrantLiabilityTableTextBlock" name="ScheduleOfFairValueMeasurementsWarrantLiabilityTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="immu_ScheduleofSharebasedCompensationPerformanceStockandPerformanceStockUnitsActivityTableTextBlock" name="ScheduleofSharebasedCompensationPerformanceStockandPerformanceStockUnitsActivityTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="immu_SeattleGeneticsIncMember" name="SeattleGeneticsIncMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="immu_SecuritiesPurchaseAgreementMember" name="SecuritiesPurchaseAgreementMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="immu_SharebasedCompensationArrangementbySharebasedPaymentAwardThresholdConsecutiveTradingDays" name="SharebasedCompensationArrangementbySharebasedPaymentAwardThresholdConsecutiveTradingDays" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="immu_SharebasedCompensationArrangementbySharebasedPaymentAwardWarrantsExercisesinPeriod" name="SharebasedCompensationArrangementbySharebasedPaymentAwardWarrantsExercisesinPeriod" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="duration" />
  <xsd:element id="immu_StockIssuedDuringPeriodValueWarrantsExercised" name="StockIssuedDuringPeriodValueWarrantsExercised" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="immu_SullivanAgreementMember" name="SullivanAgreementMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="immu_UpfrontCashPaymentAndOtherPaymentsReceivedUnderCollaborationAgreement" name="UpfrontCashPaymentAndOtherPaymentsReceivedUnderCollaborationAgreement" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="immu_WarrantIssuedNumber" name="WarrantIssuedNumber" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="duration" />
  <xsd:element id="immu_WarrantsIssuedValue" name="WarrantsIssuedValue" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="immu_WarrantsissuedinOctober2016Member" name="WarrantsissuedinOctober2016Member" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="immu_Warrantsissuedon10February2017Member" name="Warrantsissuedon10February2017Member" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="immu_WeightedaveragegrantdatefairvalueRollForward" name="WeightedaveragegrantdatefairvalueRollForward" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="immu_WeightedaverageremainingcontractualtermyearsRollForward" name="WeightedaverageremainingcontractualtermyearsRollForward" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
</xsd:schema>
