<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-12-16</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000720002</issuerCik>
        <issuerName>MAINSOURCE FINANCIAL GROUP</issuerName>
        <issuerTradingSymbol>MSFG</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001256237</rptOwnerCik>
            <rptOwnerName>BARRON WILLIAM G</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>726 HARVARD DRIVE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>OWENSBORO</rptOwnerCity>
            <rptOwnerState>KY</rptOwnerState>
            <rptOwnerZipCode>42301</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle></officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2005-12-16</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>G</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>3333</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>62297.5827</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F2"/>
                    <footnoteId id="F11"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2005-12-16</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>G</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>555</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>61742.5827</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>31917.4728</value>
                    <footnoteId id="F3"/>
                    <footnoteId id="F12"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Spouse</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>43229.9768</value>
                    <footnoteId id="F4"/>
                    <footnoteId id="F13"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Trust A</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>4917.2</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Trust B</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>205297.8063</value>
                    <footnoteId id="F5"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Barron Family Trust</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>124615.0858</value>
                    <footnoteId id="F6"/>
                    <footnoteId id="F14"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Barron Family Partnership</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>8327.6193</value>
                    <footnoteId id="F7"/>
                    <footnoteId id="F15"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>FBO Daughter</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3100.309</value>
                    <footnoteId id="F8"/>
                    <footnoteId id="F16"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>FBO Son</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>10529.4033</value>
                    <footnoteId id="F9"/>
                    <footnoteId id="F17"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>FBO Son</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>9495.5434</value>
                    <footnoteId id="F10"/>
                    <footnoteId id="F18"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>FBO Son</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>419.35</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>FBO Children</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes>
        <footnote id="F1">Includes 10,572.4821 Shares that were transferred 11/07/2005 from Indirect ownership of William G. Barron Enterprises to Direct ownership of William G. Barron.</footnote>
        <footnote id="F2">Includes 371.3654 Shares acquired on 9/15/2005, 391.2126 Shares acquired on 6/15/05, and 304.3339 Shares acquired on 3/15/05 under the MainSource dividend reinvestment plan.</footnote>
        <footnote id="F3">Includes 210.0405 Shares acquired on 9/15/2005, 221.5364 Shares acquired on 6/15/05, and 172.3394 Shares acquired on 3/15/05 under the MainSource dividend reinvestment plan.</footnote>
        <footnote id="F4">Includes 301.6589 Shares acquired on 9/15/2005, 318.1689 Shares acquired on 6/15/05, and 247.5119 Shares acquired on 3/15/05 under the MainSource dividend reinvestment plan.</footnote>
        <footnote id="F5">Includes 434.6157 Shares acquired on 9/15/2005 under the MainSource dividend reinvestment plan.</footnote>
        <footnote id="F6">Includes 869.5632 Shares acquired on 9/15/2005, 900.6186 Shares acquired on 6/15/05, and 700.6153 Shares acquired on 3/15/05 under the MainSource dividend reinvestment plan.</footnote>
        <footnote id="F7">Includes 58.1097 Shares acquired on 9/15/2005, 61.1585 Shares acquired on 6/15/05, and 47.5771 Shares acquired on 3/15/05 under the MainSource dividend reinvestment plan.</footnote>
        <footnote id="F8">Includes 21.6340 Shares acquired on 9/15/2005, 21.5923 Shares acquired on 6/15/05, and 16.7969 Shares acquired on 3/15/05 under the MainSource dividend reinvestment plan.</footnote>
        <footnote id="F9">Includes 73.4740 Shares acquired on 9/15/2005, 76.6899 Shares acquired on 6/15/05, 59.6585 Shares acquired on 3/15/05 under the MainSource dividend reinvestment plan.</footnote>
        <footnote id="F10">Includes 66.2595 Shares acquired on 9/15/2005, 69.2211 Shares acquired on 6/15/05, 53.8486 Shares acquired on 3/15/05 under the MainSource dividend reinvestment plan.</footnote>
        <footnote id="F11">Includes 2,557.9975 Shares acquired on 1/15/05 through Stock Dividend.</footnote>
        <footnote id="F12">Includes 1,404.5968 Shares acquired on 1/15/05 through Stock Dividend.</footnote>
        <footnote id="F13">Includes 2,017.2682 Shares acquired on 1/15/05 through Stock Dividend.</footnote>
        <footnote id="F14">Includes 5,710.1446 Shares acquired on 1/15/05 through Stock Dividend.</footnote>
        <footnote id="F15">Includes 387.7646 Shares acquired on 1/15/05 through Stock Dividend.</footnote>
        <footnote id="F16">Includes 136.8983 Shares acquired on 1/15/05 through Stock Dividend.</footnote>
        <footnote id="F17">Includes 486.2323 Shares acquired on 1/15/05 through Stock Dividend.</footnote>
        <footnote id="F18">Includes 438.8769 Shares acquired on 1/15/05 through Stock Dividend.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>William G. Barron</signatureName>
        <signatureDate>2005-12-16</signatureDate>
    </ownerSignature>
</ownershipDocument>
