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Note 1 - Description of Business (Details Textual)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Nov. 07, 2024
USD ($)
$ / shares
shares
Nov. 22, 2022
USD ($)
Nov. 30, 2024
USD ($)
Dec. 31, 2024
USD ($)
Dec. 31, 2027
USD ($)
Dec. 31, 2026
USD ($)
Dec. 31, 2025
USD ($)
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Nov. 01, 2024
USD ($)
Oct. 31, 2024
USD ($)
Operating Income (Loss)               $ (18,845) $ (17,259)    
Net Cash Provided by (Used in) Operating Activities               (18,047) (5,249)    
Cash and Cash Equivalents, at Carrying Value       $ 31,741       31,741 43,652    
Percentage of Workforce     25.00%                
Savings From Reduction in Workforce     $ 4,300                
Restructuring Charges       $ 600              
Number of Directors                   5 8
Board of Directors, Annual Cash Compensation, Liability                   $ 100 $ 500
Authorized Value Of Securities Registered and Sold   $ 100,000                  
Restructuring Charges, Statement of Income or Comprehensive Income [Extensible Enumeration]       Nonoperating Income (Expense)              
Prefunded Warrants [Member]                      
Class of Warrant or Right, Outstanding (in shares) | shares 2,934,690                    
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares $ 0.001                    
Line of Credit [Member] | Perceptive Credit Agreement [Member]                      
Debt Instrument, Covenant, Twelve Month Net Revenue Target, Year One               34,400      
Debt Instrument, Minimum Cash Balance $ 3,000                    
Line of Credit [Member] | Perceptive Credit Agreement [Member] | Forecast [Member]                      
Debt Instrument, Covenant, Twelve Month Net Revenue Target, Year Two             $ 37,000        
Debt Instrument, Covenant, Twelve Month Net Revenue Target, Year Three           $ 52,400          
Debt Instrument, Covenant, Twelve Month Net Revenue Target, Year Four         $ 60,300            
Debt Instrument, Maximum Operating Expense Covenant           $ 45,000 $ 40,000        
ATM Facility [Member]                      
Authorized Value Of Securities Registered and Sold   $ 40,000                  
Registered Direct Offering [Member]                      
Proceeds from Issuance or Sale of Equity $ 6,800             $ 7,000 $ 0    
Stock Issued During Period, Shares, New Issues (in shares) | shares 3,000,000