497 1 file001.txt DEFINITIVE MATERIALS Filed Pursuant to Rule 497(e) Registration File No.: 2-82510 September 24, 2003 Supplement MORGAN STANLEY LOGO SUPPLEMENT DATED SEPTEMBER 24, 2003 TO THE PROSPECTUS OF MORGAN STANLEY VARIABLE INVESTMENT SERIES CLASS Y SHARES Dated May 1, 2003 The section of the Prospectus titled "Portfolio Management -- European Growth Portfolio" is hereby replaced by the following: The Portfolio is managed within the European Growth team. Current members of the team include Jeremy G. Lodwick and Benjamin Legge.