-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0000950136-01-000628.txt : 20010410
<SEC-HEADER>0000950136-01-000628.hdr.sgml : 20010410
ACCESSION NUMBER:		0000950136-01-000628
CONFORMED SUBMISSION TYPE:	497
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20010403

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MORGAN STANLEY DEAN WITTER VARIABLE INVESTMENT SERIES
		CENTRAL INDEX KEY:			0000716716
		STANDARD INDUSTRIAL CLASSIFICATION:	UNKNOWN SIC - 0000 [0000]
		IRS NUMBER:				133178476
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		497
		SEC ACT:		
		SEC FILE NUMBER:	002-82510
		FILM NUMBER:		1592804

	BUSINESS ADDRESS:	
		STREET 1:		TWO WORLD TRADE CTR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10048
		BUSINESS PHONE:		2123922550

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	DEAN WITTER VARIABLE INVESTMENT SERIES
		DATE OF NAME CHANGE:	19930209

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	WITTER DEAN VARIABLE INVESTMENT SERIES
		DATE OF NAME CHANGE:	19920703

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	WITTER DEAN VARIABLE ANNUITY INVESTMENT SERIES
		DATE OF NAME CHANGE:	19880229
</SEC-HEADER>
<DOCUMENT>
<TYPE>497
<SEQUENCE>1
<FILENAME>0001.txt
<DESCRIPTION>DEFINITIVE MATERIALS
<TEXT>

<PAGE>

                                                Filed Pursuant to Rule 497(e)
                                                Registration File No.: 2-82510


               SUPPLEMENT DATED APRIL 2, 2001 TO THE PROSPECTUS OF
     MORGAN STANLEY DEAN WITTER VARIABLE INVESTMENT SERIES - CLASS X SHARES
                             DATED NOVEMBER 3, 2000

     The paragraph pertaining to the Income Builder Portfolio of the Fund in the
section of the Prospectus titled "PORTFOLIO MANAGEMENT" is hereby replaced by
the following:


     INCOME BUILDER PORTFOLIO - Paul D. Vance, a Managing Director of the
     Investment Manager, and Catherine Maniscalco, a Vice President of the
     Investment Manager, are the primary portfolio managers of the Portfolio.
     Mr. Vance has been a primary portfolio manager of the Portfolio since the
     Portfolio's inception in January 1997. Ms. Maniscalco has been a primary
     portfolio manager of the Portfolio since August 1999. Mr. Vance and
     Ms. Maniscalco have been portfolio managers with the Investment Manager
     for over five years.


</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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