X0303 4 2010-09-16 0 0000716646 CLINICAL DATA INC CLDA 0001091823 KIRK RANDAL J 1881 GROVE AVENUE RADFORD VA 24141 1 0 1 0 Common Stock 2010-09-16 4 A 0 15200 0 A 2326687 D Common Stock 1106672 I by R.J. Kirk DOT Common Stock 146900 I by JPK 2009 Common Stock 146900 I by MGK 2009 Common Stock 23600 I by ZSK 2009 Common Stock 32500 I by JPK 2008 Common Stock 32500 I by MGK 2008 Common Stock 32500 I ZSK 2008 Common Stock 1212 I by Lotus Capital Common Stock 1626722 I by Kirkfield Common Stock 692617 I by Staff01 Common Stock 24240 I by Incentive08 Common Stock 48478 I by Staff08 Common Stock 48478 I by SenStaff08 Common Stock 1049877 I by NRM II Common Stock 290014 I by NRM III Common Stock 3380985 I by NRM V Randal J. Kirk (2000) Limited Partnership, RJK, L.L.C, and Zhong Mei, L.L.C. were liquidated effective as of November 30, 2009 and in connection therewith the assets, including CLDA shares held thereby, were distributed pro-rata to the beneficial owners of such entities or their designees. Such transactions constituted a change in form of beneficial ownership; Randal J. Kirk continues to control each of the resulting owners of the distributed CLDA shares: R.J. Kirk Declaration of Trust ("R.J. Kirk DOT"), JPK 2009, LLC ("JPK 2009"), MGK 2009, LLC ("MGK 2009"), ZSK 2009, LLC ("ZSK 2009"), JPK 2008, LLC ("JPK 2008"), MGK 2008, LLC ("MGK 2008"), ZSK 2008, LLC ("ZSK 2008"), and Lotus Capital (2000) Company, Inc. ("Lotus Capital"). Randal J. Kirk controls each of R.J. Kirk DOT, JPK 2009, MGK 2009, ZSK 2009, JPK 2008, MGK 2008, ZSK 2008, Lotus Capital, Kirkfield, L.L.C. ("Kirkfield"), Third Security Staff 2001 LLC ("Staff01"), Third Security Incentive 2008 LLC ("Incentive08"), Third Security Staff 2008 LLC ("Staff08"), Third Security Senior Staff 2008 LLC ("SenStaff08"), New River Management II, LP ("NRM II"), New River Management III, LP ("NRM III") and New River Management V, LP ("NRM V"). Shares held by these entities may be deemed to be indirectly beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. /s/ Randal J. Kirk 2010-09-20