X0202 4 2007-02-26 0 0000716646 CLINICAL DATA INC CLDA 0001091823 KIRK RANDAL J 1881 GROVE AVENUE RADFORD VA 24141 1 0 1 0 Common Stock 1066991 D Common Stock 153353 I by Radford Common Stock 2007-02-26 4 X 0 2876 19.45 A 41719 I by Zhong Mei Common Stock 2007-02-26 4 X 0 50400 19.45 A 731083 I by RJK Common Stock 2007-02-26 4 X 0 37670 19.45 A 680504 I by Kirkfield Common Stock 2007-02-26 4 X 0 31833 19.45 A 461745 I by Staff LLC Common Stock 2007-02-26 4 X 0 48252 19.45 A 699918 I by NRM II Common Stock 2007-02-26 4 X 0 13329 19.45 A 193343 I by NRM III Warrant (right to buy) 19.45 2007-02-26 4 X 0 2876 0 D 2011-12-13 Common Stock 2876 0 I by Zhong Mei Warrant (right to buy) 19.45 2007-02-26 4 X 0 50400 0 D 2011-12-13 Common Stock 50400 0 I by RJK Warrant (right to buy) 19.45 2007-02-26 4 X 0 37670 0 D 2011-12-13 Common Stock 37670 0 I by Kirkfield Warrant (right to buy) 19.45 2007-02-26 4 X 0 31833 0 D 2011-12-23 Common Stock 31833 0 I by Staff LLC Warrant (right to buy) 19.45 2007-02-26 4 X 0 48252 0 D 2011-12-13 Common Stock 48252 0 I by NRM II Warrant (right to buy) 19.45 2007-02-26 4 X 0 13329 0 D 2011-12-13 Common Stock 13329 0 I by NRM III Randal J. Kirk controls each of new River Management III, LP ("NRM III"), Third Security Staff 2001 LLC ("Staff 2001"), Radford Investments Limited Partnership ("Radford"), Kirkfield, L.L.C. ("Kirkfield"), RJK, L.L.C. ("RJK"), Zhong Mei, L.L.C. ("Zhong Mei") and New River Management II, LP ("NRM II"). Shares held by these entities may be deemed to be indirectly beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Exercisable in full at any time six months after June 13, 2006 (the "Initial Exercise Date"), and on or prior to the close of business on the fifth year anniversary of the Initial Exercise Date. /s/ Randal J. Kirk 2007-02-27