X0101 42003-06-19 0000716054 CYPRESS BIOSCIENCE INC cypb 0000938811 DROBNY SHELDON 1000Common Stock2003-06-194M0125001.75A56500DCommon Stock2003-06-194M012213.25A57721DCommon Stock2003-06-194M022052.70A59926DCommon Stock2003-06-194M0277412.51A87667DStock Option (Right to Buy)1.752003-06-194M0125000D2001-06-112011-06-11Common Stock125000DStock Option (Right to Buy)3.252003-06-194M012210D2002-04-292012-04-29Common Stock12213154DStock Option (Right to Buy)2.702003-06-194M022050D2003-01-012013-01-01Common Stock22052795DStock Option (Right to Buy)2.512003-06-194M0277410D2003-03-272013-03-27Common Stock2774149965DTwenty-five percent (25%) of the shares subject to the option vested on June 11, 2001 with the remainder vesting over the next 12 months on a daily basis, such that all shares subject to the option will be fully vested and exercisable as of June 11, 2002.The shares subject to the option vest daily and ratably over four years beginning April 29, 2002 such that all shares subject to the option will be fully vested and exercisable as of April 29, 2006.The shares subject to the option vest daily and ratably over 12 months beginning January 1, 2003 such that all shares subject to the option will be fully vested and exercisable as of January 1, 2004.Twenty-five thousand (25,000) of the shares subject to the option vested on March 27, 2003 with the remainder vesting thereafter on a daily basis over four years, such that all shares subject to the option will be fully vested and exercisable as of March 27, 2007.Sabrina Martucci Johnson Attorney-in-Fact2003-06-20