THE PRUDENTIAL SERIES FUND, INC.

Natural Resources Portfolio


PROSPECTUS DATED MAY 1, 2004
SUPPLEMENT DATED APRIL 21, 2005


The following amends the section of the prospectus entitled
"How the Fund is Managed - Portfolio Managers":

Effective as of April 22, 2005, Leigh Goehring will be
replaced as a portfolio manager by David A. Kiefer.  Mr. Kiefer
and Michael Del Balso are the portfolio managers for the
Portfolio.

Jennison typically follows a team approach in the management
of its portfolios, while seeking to preserve individual
accountability.  The teams are generally organized along product
strategies (e.g., large cap growth, large cap value) and meet
regularly to review portfolio holdings and discuss purchase and
sales activity of all accounts in the particular product strategy.
The portfolio managers for the Portfolio are supported by
members of Jennison's research team, which is comprised of other
research analysts and other investment professionals of Jennison.
Team members provide research support and make securities
recommendations and support the portfolio managers in all
activities.  Members of the team may change from time to time.

Mr. Kiefer generally has final authority over all aspects of the
Portfolio's investment portfolio, including but not limited to,
purchases and sales of individual securities, portfolio
construction, risk assessment, and management of cash flows.
Mr. Kiefer, CFA, is an Executive Vice President of Jennison, which
he joined in September 2000.  He became head of Jennison Large
Cap Value Equity in January 2004, having managed diversified large
capitalization portfolios since 1998 and large cap blend equity
assets since 1999. He became the portfolio manager of the Jennison
Utility Fund (then Prudential) in 1994 at Prudential. He joined
Prudential's management training program in 1986. From 1988 to
1990, Mr. Kiefer worked at Prudential Power Funding Associates,
making loans to the energy industry. He then left to attend
business school, rejoining Prudential in equity asset management
in 1992.  Mr. Kiefer earned a B.S. from Princeton University and
an M.B.A. from Harvard Business School.  Mr. Del Balso joined
Jennison in 1972 and is currently an Executive Vice President at
Jennison.  Mr. Del Balso is a graduate of Yale University and
received his M.B.A. from Columbia University. He is a member of
The New York Society of Security Analysts, Inc.  Mr. Del Balso
has managed the Portfolio since April 2004.





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