Exhibit 99.1

JOINT FILERS’ SIGNATURES

ESSETIFIN S.P.A.
By:	/s/ Marino Zigrossi
Name:	Marino Zigrossi
Title:	Managing Director
Date:	September 28, 2018

Enrico Cavazza
By:	/s/ Marino Zigrossi
Name:	Marino Zigrossi
Title:	Attorney-in-fact**
Date:	September 28, 2018

Francesca Cavazza
By:	/s/ Marino Zigrossi
Name:	Marino Zigrossi
Title:	Attorney-in-fact**
Date:	September 28, 2018

Silvia Cavazza
By:	/s/ Marino Zigrossi
Name:	Marino Zigrossi
Title:	Attorney-in-fact**
Date:	September 28, 2018

Martina Cavazza Preta
By:	/s/ Marino Zigrossi
Name:	Marino Zigrossi
Title:	Title: Attorney-in-fact**
Date:	September 28, 2018

Paolo Cavazza
By:	/s/ Nicola Wullschleger
Name:	Nicola Wullschleger
Title:	Attorney-in-fact
Date:	September 28, 2018

** Power of Attorney was previously filed with Securities and Exchange Commission as an exhibit to the Form 3/A filed on October 4, 2017, with respect to the common stock of Fennec Pharmaceuticals, Inc.