-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 KZfIa8aZFe3x/xfrGujx6m+iL8PfHdW4f9wXI1X7ilEA3mHmJuXOt5a6akyY/eOl
 lWHNDX5262NCev7ia3iEDA==

<SEC-DOCUMENT>0001127602-10-002973.txt : 20100202
<SEC-HEADER>0001127602-10-002973.hdr.sgml : 20100202
<ACCEPTANCE-DATETIME>20100202085130
ACCESSION NUMBER:		0001127602-10-002973
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20100127
FILED AS OF DATE:		20100202
DATE AS OF CHANGE:		20100202

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			NATIONAL PENN BANCSHARES INC
		CENTRAL INDEX KEY:			0000700733
		STANDARD INDUSTRIAL CLASSIFICATION:	NATIONAL COMMERCIAL BANKS [6021]
		IRS NUMBER:				232215075
		STATE OF INCORPORATION:			PA
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		PHILADELPHIA AND READING AVES
		STREET 2:		PO BOX 547
		CITY:			BOYERTOWN
		STATE:			PA
		ZIP:			19512
		BUSINESS PHONE:		1-800-822-3321

	MAIL ADDRESS:	
		STREET 1:		PHILADELPHIA AND READING AVES
		STREET 2:		P. O. BOX 547
		CITY:			BOYERTOWN
		STATE:			PA
		ZIP:			19512

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			KEENE S TURNER
		CENTRAL INDEX KEY:			0001482570

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22537-01
		FILM NUMBER:		10565179

	BUSINESS ADDRESS:	
		STREET 1:		P O BOX 547
		CITY:			BOYERTOWN
		STATE:			PA
		ZIP:			19512
		BUSINESS PHONE:		610-369-6293

	MAIL ADDRESS:	
		STREET 1:		P O BOX 547
		CITY:			BOYERTOWN
		STATE:			PA
		ZIP:			19512
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>form3.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0203</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2010-01-27</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000700733</issuerCik>
        <issuerName>NATIONAL PENN BANCSHARES INC</issuerName>
        <issuerTradingSymbol>NPBC</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001482570</rptOwnerCik>
            <rptOwnerName>KEENE S TURNER</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>P. O. BOX 547</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>BOYERTOWN</rptOwnerCity>
            <rptOwnerState>PA</rptOwnerState>
            <rptOwnerZipCode>19512</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isOfficer>1</isOfficer>
            <officerTitle>Chief Accounting Officer</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes></footnotes>

    <ownerSignature>
        <signatureName>/s/ Michelle H. Debkowski, by power of attorney</signatureName>
        <signatureDate>2010-02-01</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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