Consolidated Statements of Shareholders' Equity (USD $)	Common stock	Additional paid-in capital	Accumulated other comprehensive income	Accumulated deficit	Total
Beginning balances at Dec. 31, 2010	$ 13,000	$ 400,880,000	$ (30,000)	$ (379,030,000)	$ 21,833,000
Beginning balances, shares at Dec. 31, 2010	12,809,000
Share-based compensation expense	0	3,356,000	0	0	2,286,000
Share-based compensation expense, shares	218,000
Exercise of warrants and options	0	70,000	0	0	23,000
Exercise of warrants and options, shares	5,000				5,000
Sales of common stock and warrants	4,000	21,352,000	0	0	14,601,000
Sales of common stock and warrants, shares	3,987,000
Other comprehensive income (loss)			(5,000)		(5,000)
Net loss				(35,808,000)	(35,808,000)
Ending balances at Dec. 31, 2011	17,000	425,658,000	(35,000)	(414,838,000)	10,802,000
Ending balances, shares at Dec. 31, 2011	17,019,000
Share-based compensation expense		2,286,000
Share-based compensation expense, shares	648,000
Exercise of warrants and options		23,000
Exercise of warrants and options, shares	16,000				16,000
Sales of common stock and warrants	8,000	14,593,000
Sales of common stock and warrants, shares	7,554,000
Other comprehensive income (loss)			35,000		3,000
Net loss				(22,693,000)	(22,693,000)
Ending balances at Dec. 31, 2012	$ 25,000	$ 442,560,000	$ 0	$ (437,531,000)	$ 5,054,000
Ending balances, shares at Dec. 31, 2012	25,237,000