Consolidated Statements of Shareholders' Equity (USD $) In Thousands	Common stock	Additional paid-in capital	Accumulated other comprehensive income	Accumulated deficit	Total
Beginning balances at Dec. 31, 2008	$ 9	$ 319,721	$ (38)	$ (292,041)	$ 27,651
Beginning balances, shares at Dec. 31, 2008	8,510
Share-based compensation expense	0	3,335	0	0	3,335
Share-based compensation expense, shares	3
Exercise of warrants and options	0	4,794	0	0	4,794
Exercise of warrants and options, shares	184
Sales of common stock and warrants	2	45,633	0	0	45,635
Sales of common stock and warrants, shares	2,389
Issuance of common stock for payment of intellectual property					0
Other comprehensive income	0	0	5	0	5
Net loss	0	0	0	(39,529)	(39,529)
Ending balances at Dec. 31, 2009	11	373,483	(33)	(331,570)	41,891
Ending balances, shares at Dec. 31, 2009	11,086
Share-based compensation expense	0	3,601	0	0	3,601
Share-based compensation expense, shares	11
Exercise of warrants and options	0	478	0	0	478
Exercise of warrants and options, shares	30
Sales of common stock and warrants	2	21,618	0	0	21,620
Sales of common stock and warrants, shares	1,578
Issuance of common stock for payment of intellectual property	0	1,700	0	0	1,700
Issuance of common stock for payment of intellectual property, shares	104
Other comprehensive income	0	0	3	0	3
Net loss	0	0	0	(47,460)	(47,460)
Ending balances at Dec. 31, 2010	13	400,880	(30)	(379,030)	21,833
Ending balances, shares at Dec. 31, 2010	12,809
Share-based compensation expense	0	3,356	0	0	3,356
Share-based compensation expense, shares	218
Exercise of warrants and options	0	70	0	0	70
Exercise of warrants and options, shares	5
Sales of common stock and warrants	4	21,352	0	0	21,356
Sales of common stock and warrants, shares	3,987
Issuance of common stock for payment of intellectual property					0
Other comprehensive income	0	0	(5)	0	(5)
Net loss	0	0	0	(35,808)	(35,808)
Ending balances at Dec. 31, 2011	$ 17	$ 425,658	$ (35)	$ (414,838)	$ 10,802
Ending balances, shares at Dec. 31, 2011	17,019