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Stock Plans and Stock-Based Compensation (Details Textual) - USD ($)
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Dec. 31, 2018
Oct. 31, 2006
Stock Plans and Stock-Based Compensation (Textual)        
Total compensation expense recognized related to stock option awards $ 4,836 $ 13,335    
Weighted average fair value of option $ 0.05      
Option [Member]        
Stock Plans and Stock-Based Compensation (Textual)        
Stock option outstanding     8,847,351  
Stock option exercisable     34,750  
Common stock fair value $ 0.04      
Option outstanding aggregated intrinsic value     $ 10,008,001  
Selling, General and Administrative Expenses [Member]        
Stock Plans and Stock-Based Compensation (Textual)        
Total compensation expense recognized related to stock option awards $ 4,269 11,487    
Research and Development Expense [Member]        
Stock Plans and Stock-Based Compensation (Textual)        
Total compensation expense recognized related to stock option awards $ 567 $ 1,848    
Stock Compensation Plan One [Member]        
Stock Plans and Stock-Based Compensation (Textual)        
Stock options vesting periods 4 years      
Stock options contractual terms 10 years      
Stock option exercisable       18,000,000
Total unrecognized compensation cost related to nonvested share-based compensation arrangements $ 12,874