-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, Lsfd1kTC4CxAf2xrG+Bn89/mdAEW/YSVA6qjtajAFDJNpu6iSQfeO90IuNoUZXqM uwcOPLyLxWHnuh3YtsJCjw== 0000914317-07-001680.txt : 20070613 0000914317-07-001680.hdr.sgml : 20070613 20070613164621 ACCESSION NUMBER: 0000914317-07-001680 CONFORMED SUBMISSION TYPE: 10KSB PUBLIC DOCUMENT COUNT: 4 CONFORMED PERIOD OF REPORT: 20070228 FILED AS OF DATE: 20070613 DATE AS OF CHANGE: 20070613 FILER: COMPANY DATA: COMPANY CONFORMED NAME: MEDISCIENCE TECHNOLOGY CORP CENTRAL INDEX KEY: 0000064647 STANDARD INDUSTRIAL CLASSIFICATION: SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841] IRS NUMBER: 221937826 STATE OF INCORPORATION: NJ FISCAL YEAR END: 0228 FILING VALUES: FORM TYPE: 10KSB SEC ACT: 1934 Act SEC FILE NUMBER: 000-07405 FILM NUMBER: 07917851 BUSINESS ADDRESS: STREET 1: 1235 FOLKESTONE WY CITY: CHERRY HILL STATE: NJ ZIP: 08034 BUSINESS PHONE: 6094287952 MAIL ADDRESS: STREET 1: 1235 FOLKESTONE WAY CITY: CHERRY HILL STATE: NJ ZIP: 08034 FORMER COMPANY: FORMER CONFORMED NAME: CARDIAC TECHNIQUES INC DATE OF NAME CHANGE: 19730920 10KSB 1 form10ksb-85033_mdsc.txt UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-KSB (Mark One) [X] ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended February 28, 2007 [_] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from _______ to ________ Commission file number 33-51218 MEDISCIENCE TECHNOLOGY CORP. (Name of small business issuer in its charter) New Jersey 22-1937826 (State or other jurisdiction of (I.R.S. Employer Identification No.) incorporation or organization) 1235 Folkestone Way Cherry Hill, New Jersey 08034 (Address of principal executive offices) (Zip Code) Issuer's telephone number: (215) 485 0362 Securities registered under Section 12(b) of the Exchange Act: Title of each class Name of each exchange on which registered None Securities registered under Section 12(g) of the Exchange Act: Common stock, $.01 par value (Title of class) Check whether the issuer is not required to file reports pursuant to Section 13 or 15(d) of the Exchange Act. [ ] Check whether the issuer (1) filed all reports required to be filed by Section 13 or 15(d) of the Exchange Act during the past 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes [X] No [ ] Check if there is no disclosure of delinquent filers in response to Item 405 of Regulation S-B contained in this form, and no disclosure will be contained, to the best of registrant's knowledge, in definitive proxy or information statements incorporated by reference in Part III of this Form 10-KSB or any amendment to this Form 10-KSB. [X] Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes [ ] No [X] The issuer's revenues for the most recent fiscal year, ended February 28, 2007, were $-0-. The aggregate market value of the issuer's voting and non-voting common equity held by non-affiliates, computed by reference to the average of the closing bid and ask price reported on the OTC Bulletin Board on May 31, 2007, was approximately $5,752,707. As of May 31, 2007, there were outstanding 65,459,274 shares of the issuer's common stock, $.01 par value. DOCUMENTS INCORPORATED BY REFERENCE None Transitional Small Business Disclosure Format (Check one): Yes [ ] No [X] Table of Contents ----------------- Page ---- PART I - ------ Item 1. Description of Business........................................ Item 2. Description of Property........................................ Item 3. Legal Proceedings.............................................. Item 4. Submission of Matters To A Vote Of Security Holders............ PART II - ------- Item 5. Market for Common Equity and Related Stockholder Matters....... Item 6. Management's Discussion and Analysis........................... Item 7. Financial Statements........................................... Item 8. Changes in and Disagreements with Accountants on Accounting and Financial Disclosure........................................... Item 8A. Controls and Procedures........................................ Item 8B. Other Information.............................................. PART III - -------- Item 9. Directors, Executive Officers, Promoters , Control Persons and Corporate Governance; Compliance with Section 16 (a) of the Exchange Act................................................... Item 10. Executive Compensation......................................... Item 11. Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters................................ Item 12. Certain Relationships and Related Transactions, and Director Independence................................................... Item 13. Exhibits....................................................... Item 14. Principal Accountant Fees and Services......................... -i- SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS ------------------------------------------------- Certain statements in this Annual Report on Form 10-KSB, including statements under "Item 1. Description of Business," and "Item 6. Management's Discussion and Analysis," contain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, including but not limited to our assumptions underlying our statements concerning business strategy, development and introduction of new products, research and development, marketing, sales and distribution, manufacturing, competition, third-party reimbursement, government regulation (including, but not limited to, FDA requirements), continued clinical trial relationships and operating and capital requirements, critical accounting determinations; efforts to raise additional financing; and our commitment of resources. The forward-looking statements may also be impacted by the additional risks faced by us as described in this report, including those set forth under the section entitled "Risk Factors." Forward-looking statements generally can be identified by the use of terminology such as "may," "will," "expect," "intend," "estimate," "anticipate" or "believe" or similar expressions or the negatives thereof. These expectations are based on management's assumptions and current beliefs based on currently available information. Although we believe that the expectations reflected in such statements are reasonable, we can give no assurance that such expectations will be correct. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this annual report on Form 10-KSB. Our operations are subject to a number of uncertainties, risks and other influences, many of which are outside our control, and any one of which, or a combination of which, could cause our actual results of operations to differ materially from the forward-looking statements. -ii- PART I Item 1. Description of Business Background The Company operates in one business segment and is principally engaged in the design and development of medical diagnostic instruments that detect cancer in vivo in humans by using light to excite the molecules contained in tissue and measuring the differences in the resulting molecular natural fluorescence between cancerous and normal tissue. (e.g IP platform products ,CD-Ratiometer-- March 29, 2006 FDA approved pilot clinicals as "Adjunct to the Pap Smear" and the Photonic ingestible Pill (See 8-K's March 26, 2006) Registrants business is to deploy commercially the Mediscience IP platform technology of light spectroscopy to diagnose diseases: Non-invasively (where excisional biopsies and x-rays are avoided, More reliable (where pathology is verified) More rapidly: real time point of care diagnostics (where pathology laboratory evaluation is supplanted). On December 1, 1988, registrant acquired Laser Diagnostic Instruments, Inc. ("LDI"), a wholly owned subsidiary whose principle asset was a patent "Method and Apparatus for Detecting Cancerous Tissue Using Visible Luminescence," US patent number 4,930,516 June 5, 1990. On August 8, 1998 in a US Patent Office re-examination. the "516" claims were expanded from 9 to 59. Our research and development activities are clustered around this patent and 26 related patents acquired by Mediscience as either owner or exclusive licensee. The fundamental process used by these patents is the interpretation of optical imaging data gathered by exposing select areas of tissue to various forms of electromagnetic radiation. Our work with co-founder Dr Robert Alfano demonstrates that the use of fluorescence leaves provides a different and distinct molecular "signature"from normal or cancerous tissue. That signature, in turn, can be converted into a specific algorithm that can distinguish malignant tissue from normal tissue." Our collective IP claims inter-relate in the process of non-invasively detecting cancerous tissue within the body. Registrant regards its related patent cluster as pioneering, and seminal in the area of cancer and physiological change diagnosis using its IP fluorescence spectroscopy both in-vivo and in-vitro. Registrant believes the Company's technology, if successfully developed commercially will have enhanced diagnostic sensitivity and specificity with substantial commercial appeal due to its: non-invasive nature and delivery of immediate results. Dr. Robert Alfano, co-founder of registrant formed Alfanix Ltd. a New York State for-profit company. (See 8-K dated March 3., 2006) under alliance contract with Registrant (see 8-K dated March 3., 2006 and 8KA dated May 18, 2006) to explore enhanced algorithmic development for the CDR (CD-Ratiometer) unit, upon Registrants discretionary, selective, sole project approval, and RFCUNY non-conflicting contract approval. Alfanix Ltd. may suggest investigative relationships to registrant for Registrants management review and Board consideration for registrants discretionary approval "Compact Photonic Explorer" (CPE): Registrant is partnered with its equity investor Infotonics Technology Center of Rochester New York (a consortium of Corning, Eastman Kodak and Xerox) and contractually acquired all Infotonics patent rights to the "Photonic Pill." Both are developing the (CPE), for medical applications to detect cancer and /or physiological change in vivo in humans. The product is being designed to take an optical biopsy at the molecular level of various areas in the human digestive tract utilizing Registrants proprietary IP molecular spectroscopy. The first project for the (CPE) is to target diagnosing various forms of cancer throughout the GI tract in real-time. The (CPE) incorporates registrants IP photonics platform that utilizes the inherent physical characteristics normal, pre-cancerous, and cancerous tissues exhibited when illuminated with light of specific frequencies. Commercialization requires specific engineering and implementation decisions be made concerning the components and composition of the pill, including the selection of a particular light emitter, light detector, power source, position detection means, and casing design. The three main competitors in the optical biopsy pill market today are Given Imaging, Olympus Optical LTD, and Smart Pill Corporation. Each company offers a product supported by a different technical platform and with inherently different capabilities. Given's PillCam involves recorded white-light optical imaging and analysis, Olympus Optical LTD's EndoCapsule involves real-time optical imaging, transmission and analysis, and SmartPill involves chemical analysis of tissue as opposed to optical imaging. Registrants and Infotonics, based on in depth market and technology review (see 8-K Mar. 26, 2006) believe that a photonics technical platform of optical biopsy - 1 - (CPE) introduces a new, better and more market promising concept into the emerging endoscopic ingestible pill market. In brief, the CPE employes autoflourescence sensing and imaging that provides diagnostic information beyond that possible with the white-light imaging used by Given and Olympus. (See CITIGROUP/Smith Barney Analyst Report 10-1-2004 by Peter Bye. Page 20 Registrant-Info tonics). (See 8-K filing w/ Syracuse University Law 57 pg. report exhibit May 26, 2006) On March 29, 2006 the FDA approved as a "Non-significant Risk Device Study, Registrants multi-center pilot study approval adjunct to the PAP intended to establish the safety and parameters of efficacy of the (CD-R) for cancer detection of the cervix preliminary to a pivotal study. The CD-R unit will be used to detect changes in the cervix using a non-invasive/minimally invasive and painless optical technology with a disposable probe to identify anomalous areas, with cancerous or pre-cancerous tissues. The Purpose is to provide immediate real-time cancer diagnosis reading in the Doctors office with accuracy presently not available in the conventional PAP approach. The intent of the CD-R technology is to replace the PAP including deployment in global regions where PAP smears are not widely available. Based upon funding Registrant will commence the Pilot study observing the regulations governing patient consent and related institutional IRB approval. The FDA has provided Registrant comments and suggestions which will assist in its pilot and pivotal clinical studies. The objectives of this pilot study are to determine efficacy; the clinical sensitivity and clinical specificity (ability for the device to distinguish between tissues that are normal, benign, precancerous low grade, precancerous high grade, CIS and cancer) by comparing the device real-time results to the Pap test and biopsy; and assess any adverse events based on Good Clinical Practices. Frequency, type and intensity of clinical adverse events will also be evaluated. Assuming the results of this initial efficacy and safety study are satisfactory, in the detection of cervical cancer precursors i.e. (pre-cancerous cells), indications of possible cancer development, with FDA approval registrant will continue into its pivotal study. Strategy The Company's strategy is maximize the value of the Company's IP platform (over 25 patents in the areas of tissue spectroscopy and optical imaging with applications in cancer detection) as a modern alternative to traditional endoscopy; to commercialize real-time early cancer screening and detection devices with less invasive ways of detecting abnormalities in the human body based upon our IP platform, completed proto-type's, and expertise in the area of fluorescent molecular imaging. In addition to seeking conventional investment into the Company registrant can use its wholly owned subsidiary LLC's, each with its own IP supported application. Our first effort Medi-Photonics development LLC, (NY) is focused on early cancer screening and detection by CD-R for cervical cancer adjunct to the Pap smear. Other considered IP platform targets on early cancer are, mouth, colon, esophagus, and potential applications of its ingestible "(CPE)." The ultimate goal of registrant's optical biopsy IP is to algorithmically specifically identify whether "a tissue is malignant, dysplastic [pre-cancer] or benign; in addition to whether it is invasive cancer in any endoscopic, laproscopic or stereotactic procedure. Registrant independently and with equity investor Infotonics Research is actively exploring strategic distributors, partners, and investors. All above are Safe Harbor" statements per the Private Securities Litigation Reform Act of 1995 as certain matters and subject areas discussed in our strategy and not historical or current facts but deal with future circumstances and developments. The discussion of such matters and subject areas is qualified by the inherent risks and uncertainties surrounding future expectations generally and may also differ materially from our future experience involving any or more of such matters and subject areas. Such risks and uncertainties include overall economic trends, successful development of products and regulatory matters including but not limited to FDA as well as those more fully described from time to time in our reports filed with the SEC. Registrant contract with the Research Foundation City University of New York (RFCUNY) effective June 10, 2002 imposes registrant a royalty rate of 3.25% as to those patent/patent applications of a medical nature not totally owned by registrant. RFCUNY received the following consideration, issuance to RFCUNY of 283,228 SEC 144 shares and a five (5) year. Warrant to providing (RFCUNY) the right to purchase six hundred thousand (600,000) SEC restricted 144 shares of registrant at one dollar ($1.00) per share expiring June 10 2007. RFCUNY also received from registrant payment of all appropriate patent preparation and filing fees and all US, Japan, EU Patent Office maintenance fees associated with the patents and applications listed in Exhibit A. The agreement - 2 - affirms Registrant's ownership and/or exclusive license of all MEDICAL APPLICATIONS embodied in Registrants patent list attached to the contract as exhibit A. According to the terms registrant must negotiate a minimum royalty Agreement within 5 years of the date of filing with the RFCUNY, or all licensed patents for which product commercialization has not yet occurred. Our collective IP claims inter-relate in the process of non-invasively detecting cancerous tissue within the body thus, Registrant believes that present Mar. 29, 2006 FDA pilot approval is a significant "product commercialization" as well as the FDA effort performed by Memorial Sloan Kettering Cancer Center, supervised by Dr Stimson Schantz (see scientific advisory board for CV) using a rat esophageal model demonstrated that fluorescence could detect precancerous changes in the rat esophagus prior to any visual indication of malignancy. This in vivo oral cancer study at MSKCC was able to discern differences between normal healthy controls and "normal" appearing contra lateral sites in oral cancer patients achieving Phase I FDA approval. We currently have instrumentation which may probe the following organ sites: oral cavity, cervix, aero-digestive tract and colon. Use in the aerodigestive tract and colon requires that our instrumentation be coupled to an endoscope. We have already coupled our instrumentation to various GI tract endoscopes and our technology is embedded in the (CPE) photonic pill patent. The Products Registrant is developing products in the areas of cervical, probe GI, ingestible pill camera, and oral cavity probe that employ Molecular Optical Biopsy IP for cancer screening and diagnosis. The Company's devices are based upon the Company's Cancer Detection ("CD") Scan, CD Ratiometer and CD Map. These devices use lamplight to provide a broad spectrum of safe, scanning excitation light wavelengths to insure that the appropriate target tissue molecules are sufficiently fluoresced to provide maximum diagnostic sensitivity. A fiber optic probe is attached to each of our devices to transmit the optical excitation signal. The CD instruments demonstrate a great deal of versatility and a broad range of potential platform applications depending on the designated configuration of the fiber optic probe and associated imaging optics. The probe can be configured as hand held for easy-to-access areas such as the oral cavity or the skin surface, or it can be fed down the working channel of a Rigid or Flexible Endoscopes for assessment of the upper or lower GI tract, or through a Cystoscope for study of the urinary tract, or Colposcope for gynecological evaluation or Laparoscope's for evaluation of internal organs, and fed through a core biopsy needle to optically assess breast tumors or other deep tissue tumors, e.g. the pancreas, liver or prostate. The CD Scan is used in medical research to help define the critical scanning and emission wavelengths for our two other prototypes products. It provides optical scanning capability over a broad spectrum of optical wavelengths for the evaluation of tissue. The CD-Ratiometer (FDA Mar. 29, 2006 approved for Pilot clinicals) is a compact instrument with user-friendly features and characteristics and has been designed to optically assess the target tissue only at pre-established optical wavelengths and to instantaneously report out a "yes "no" or "maybe" result on a computer screen. The CD-Ratiometer will provide fluorescence images of target tissue as well as computed diagnostic information. We expect that the CD Ratiometer with its anticipated assortment of disposable probe designs will be the preferred product for medical practitioners to use in the office or clinical setting. The Compact Photonic Explorer (CPE), Infotonics/Registrants Pill is being designed with the merging of optical imaging techniques (fluorescent light, excited photonic light, and varying spectroscopy techniques) and Infotonics nano-technology miniature-scaling attributes and capabilities. Such compact devices use three-dimensional mechanical components of various configurations on a miniaturized scale including an optical component, resulting in a Molecular Optical Biopsy Pill system. Registrant and Infotonics believe the CPE would provide the ability to treat cancer through manipulation of visible and ultra-violet fluorescence incorporating the science of registrant's photonics cancer-detection IP platform to the (CPE) thus quickly and accurately detecting and treating cancerous and pre-cancerous growths in vivo. - 3 - Research and Product Development The utility of native tissue fluorescence spectroscopy for in vivo cancer detection in humans was first discovered in the early 1980's by Dr. Robert Alfano co-founder of registrant, and President of Alfanix: (see Alfano CV, chairman of registrant's scientific advisors). Dr. Alfano is currently employed as a faculty member affiliated with the physics department at CUNY since 1972. In 1992, registrant financially assisted in the establishment of the Medi-photonics Laboratory ("MPL") at the City College of New York to provide research and development services in the area of tissue spectroscopy and cancer detection and other biological applications. The staff of MPL, which is supervised by Dr. Alfano, developed several generations of the CD prototype device and has conducted in vitro, pre-clinical testing of various human tissue types to develop the preferred optical scanning and emission wavelengths that yield the most definitive information about native fluorescence characteristics of specific scanned tissue. The insight gained from this work has been the principal source of knowledge for the issued and pending patents which registrant owns outright or possesses world wide exclusive license. This in-vitro pre-clinical research and development work also provided the starting basis for the optical scanning parameters for the Company's in vivo human clinical studies. Clinical Development Registrant's products are designed primarily to be used directly on human patients in-vivo. Part of the process of product development and FDA approval is the development of sufficiently compelling clinical evidence to demonstrate safety and effectiveness of one or more of the Company's prototype CD products for each intended diagnostic application (labeled or intended use). Because of potential clinical utility of our technology and prototype CD products, we have developed collaborative clinical relationships with highly regarded cancer center research hospitals in the United States to assist in FDA clinical evaluations of our prototype products, present and future. These institutions include Memorial Sloan-Kettering Cancer Center, Columbia Presbyterian Hospital and the New York Hospital (Cornell Medical Center), each of New York, and the Massachusetts General Hospital (Harvard Medical School) in Boston. An FDA approved Phase I clinical feasibility study of the upper aero-digestive tract was carried out at Memorial Sloan-Kettering under the principal investigation of Stimson P. Schantz, M.D., Associate Professor of Surgery and Director of Cancer Prevention, member of Registrants scientific Board. It was established in this Phase I FDA approved study that the Company's CD Scan prototype product is able to distinguish between cancerous and normal tissue in the oral cavity using its technology. Phase II and III clinical studies in the upper aero-digestive tract can be submitted for FDA consideration on funding availability. Registrant intends to re-visit this important area in the future. An FDA Phase I clinical study could be conducted at New York Hospital's Cornell Medical Center to assess the potential utility of the Company's CD Ratiometer with fiberoptic probe adapted to a flexible endoscope for monitoring Barrett's Esophagus. On April 24, 1997, we entered into a clinical trial agreement and provided initial funding for this Institutionally (IDE) approved clinical study. However, further progress on this study through the FDA will require additional funding which cannot be provided at this time due to resource constraints. Barrett's Esophagus is thought to be a possible precursor to esophageal cancer requiring routine monitored because of the predisposition to esophageal cancer. Current medical practice requires that multiple excisional biopsies be taken to monitor the progression of disease. The practice is painful, costly and probably unnecessary in the majority of Barrett's patients, but the current state of medical practice does not provide sufficient molecular information to distinguish between the high risk group and the lower risk group. Registrant believes that endoscopic application of our technology will provide gastroenterologists with additional molecular information and the ability to better assess the condition of Barrett's tissue without a need for painful multiple biopsies and establish individual patient monitoring schedules. Dr. Basuk reported his work supports registrants UV emission measurements which can distinguish normal esophageal tissue from Barrett's or adenocarcinoma. Preliminary data indicates that the combination of UV emission and Excitation measurements can potentially separate Barrett's from dysplasia and cancer as well as from normal tissues. On March 19, 1999 the NEW ENGLAND JOURNAL of MEDICINE (Vol.340, No. 11) reported "Symptomatic Gastrosophageal Reflux as a risk factor for esophageal Adenocarcinoma," concluding that there is a - 4 - strong and probable causal relation between gastrosophageal reflux and esophageal adenocarcinoma. Esophageal adenocarcinoma is treatable but rarely curable, mortality is high and any chance of successful treatment depends on early detection, thus screening high-risk patients using registrants CD Ratiometer with fiberoptic probe would be desirable. Registrants supporting experience in Excitation of important tissue molecules shows improved diagnostic accuracy in the range of 80 to 90 percent with measurement time of a few seconds (real-time). Business Development and Marketing The market for optical biopsy-related products is intertwined with the impact of cancer on society and the benefits incurred through early detection via various medical devices. The National Institute of Health reports cancer is responsible for one out of every four deaths in the United States. Approximately 400,000 to 500,000 people in the United States died of one or more cancers yearly. The financial costs of cancer reported in 2005, direct: medical costs of cancer care totaled $74 billion, lost productivity and other effects added an additional $136 billion. More than 1,200,000 new cancer cases are diagnosed annually in the United States according to the American Cancer Society and as many as 85 million people currently alive in the United States, nearly 1/3 of the population, will develop cancer during their lifetimes. Cancer therapy has progressed rapidly in recent years but the axiom that early diagnosis is critical for successful treatment for the majority of cancer types still remains true. Registrant early diagnosis IP platform suggests broad application potential. Registrant has chosen as its first entry the improvement of Pap tests. Cervical cancer is the second most common cancer among women. The cancer is usually caused by common papilloma viruses, which are spread through sexual contact. The Pap smear is the most widely used screening technique (some 50 million PAP smears are performed in the U.S. annually) in which cervical cells collected by physicians are sent to laboratories for analysis (the total cost ranges between $35-$50); however, the Pap test generates a significant number of both false positive (as much as 40-50%) and false negative results (as much as 20-40%). The Company believes that its photonics technology offers the ability to significantly improve sensitivity and specificity (to >90%), with potential cost savings to the health care system in excess of $1B annually. If one penetrates only 1% of the PAP market with registrants CD-R after market approval by the FDA the sales for product ands disposables would be significant. Although several cancer screening techniques have been developed for the early indication of various types of cancer in humans, such as, mammography for breast cancer, PAP tests for cervical cancer, PSA tests for prostate cancer and chest x-rays for lung cancer, excision biopsy is still the "gold standard" for making a definitive cancer diagnosis and for cancer staging, i.e., determining the extent of the progression of the disease prior to mapping out the most appropriate course of therapy. The excision biopsy requires a significant amount of surgical intervention to collect an adequate tissue sample to make a proper diagnosis and staging determinations. The process can sometimes expose the patient to unnecessary risks, lengthy hospital stays, long recovery times, pain and discomfort and significant health care expense. The Company's technology is believed to offer the potential of a less physically invasive method to diagnose and stage a variety of cancers without the excessive costs and potentially debilitating effects of biopsy. The most widely practiced technique for definitive diagnosis of breast cancer, the leading cause of death among American women between the ages of 40 and 55, is open surgical biopsy (a specific type of biopsy) which is done under a general anesthetic and typically results in surgical excision of a golf ball-sized mass of breast tissue. About 800,000 such procedures are performed annually in the United States at an estimated annual cost of between $2 billion and $4 billion. If the Company can successfully adapt its technology to diagnose and stage breast cancers, it believes it will save up to half the current cost by reducing and /or eliminating extensive hospital stays and frequency of surgery as well as impacting significantly the amount of patient discomfort for those patients medically determined to have cancer, and eliminate most of the trauma for the 70% to 80% of the patients who are found not to have cancer. We believe that our technology incorporated into one or more of our prototype CD products will be useful in diagnosing and staging for a wide range of the more than 100 known types of cancers. In addition to the pre-clinical and clinical evaluations currently projected or already completed, i.e., upper aerodigestive tract, breast and esophagus, we are in the process of creating a prioritized list of other potential applications to evaluate on a pre-clinical basis. If successful, on a pre-clinical basis, we contemplate progressing to the clinical evaluation phase and pre-market approval ("PMA") application phase. - 5 - We plan to develop certain of our CD products for diagnostic applications, (sometimes referred to as "labeled indications"), that we will ultimately market for our own account in the United States. In addition, we desire to co-develop one or more of our prototype CD products for specific cancer diagnostic applications with one or more selected other companies. We continue to seek relationships with highly qualified companies which have expressed interest in our IP space. We have, in the past, and continue to encourage any possible collaboration especially with firms that have strong existing franchises in certain specialized fields of diagnosis and treatment and who have established reputations with prospective purchasers of diagnostic products and who have proven selling, marketing and distribution capabilities. A select number of these kinds of relationships, if we are successful in fostering them, are expected to add value to the Company by leveraging our financial resource base with development and licensing revenues that the Company can then use to help fund the development of its own products. We also believe that a market for our CD products will exist in Latin America, Africa, India the European Union and possibly Asia. We contemplate making a concerted effort to identify one or more possible licensees to help develop our products or variations thereof for key markets during 2007-2008 Manufacturing Our prototype products have been assembled through 2006 by the staff of the MPL at the City College of New York from components that are generally readily available from one or more sources in the marketplace. Starting in 2007, reengineered prototypes will be developed through our New York subsidiary BioScopix inc. and equity associate Info tonics Technology Center, using advanced optical components that will positively impact overall system cost and size. Although additional design improvements will likely be required to refine the current prototype products for commercial use, we still believe that the key components will be available from one or more suppliers. The manufacture of our products will be carried out by our New York subsidiary BioScopix Inc. As needed BioScopix Inc. will use manufacturing contractors who will be selected from a list of highly qualified New York companies who are familiar with the regulatory requirements of the FDA for the manufacture of medical devices, who are registered with and in good standing with the FDA and who employ current Good Manufacturing Practices (GMP) in accordance with FDA guidelines. Additionally, an opportunity for a business arrangement with a major marketing co-developer could involve manufacture as well. We have also discussed with Infotonics Research the establishment of Registrants BioScopix Inc incubation site for business purposes and on site manufacturing at their Rochester NY campus. This location would include New York State tax abatement benefits as well as the potential for Empire State EDA funding and NYSTAR grants. Competition CD-R Our IP Platform of Molecular In-vivo tissue autofluorescence and spectral analysis represents a new diagnostic paradigm. The goal of optical biopsy is determine whether "a tissue is malignant, dysplastic [pre-cancer] or benign; in addition to whether it is invasive cancer. The use of fluorescence produces a different "signature" depending on whether it is used on normal or cancerous tissue. That signature, in turn, can be converted into an algorithm that can distinguish malignant tissue from normal tissue. Registrant believes its methods are less invasive than traditional surgical biopsies --no tissue is excised from the body, results are instantaneous, more sensitive to change, and possibly more accurate than other methods. Our IP when developed offers the promise of providing cost effective and user friendly screening with increased sensitivity and specificity, and ultimately, replacing excision biopsy as the diagnostic gold standard. There is intense competitive activity in this area; with at least seven companies to date conducting active research and development programs, as well as the recent development of FDA approved HPV vaccines. Current screening systems are dominated by the Pap smear and colposcopy, as well established and pervasive, and now the entry of Vaccines (Merck Glaxo). Improvements and new technologies for cervical cancer detection include Digene Corp. human papilloma Virus testing and Cytyc Corp's "Thin-Prep." There are companies and institutions attempting to develop products using bio-photonic technologies in cervical cancer detection including Spectrx Inc, MD Anderson, and University of Michigan. Mediscience/BioScopix Inc. and its equity - 6 - associates RFCUNY, and Infotonics Technology Center will continue to develop devices that are more accurate, easier to use and/or less costly to administer to maintain competitive advantage. Of special interest are HPV vaccines: by Merck and Glaxo. Registrant's screening and Vaccination, are complimentary - each providing a tool to fight cervical cancer. HPV has two different target populations. The first is those who have not been infected with HPV, but are at risk for infection. This population is in need of prevention. The second consists of those already infected with HPV and those who will become infected (subjects for whom prevention failed or not yet available). This population is in need of continual screening, diagnosis, treatment and post-treatment monitoring. For the first group, vaccination is the important part of the solution and there are many issues which may take significant time to resolve (i.e. vaccines efficiency, need for repeated boosters, duration of immunization, failure of immunization, emergence of new strains of viruses, etc). Merck's short studies show that their vaccine only targets two carcinogenic strains of HPV (HPV 16 and 18) out of 35 sexually transmitted strains of the virus. HPV 16 and 18, combined are responsible for 2/3 of cervical cancer and pre-cancer cases. The other 33 strains as well as other potential but unknown factors, which are not prevented by the vaccine, are responsible for the other 1/3 of the cases. It will take many years to vaccinate a significant fraction of the worlds at risk population. During this period, the CD-Ratiometer can provide an efficient, cost effective, screening tool. Merck advises that despite the results obtained with their vaccine, patients MUST BE FOLLOWED WITH PAP SMEARS indefinitely. The vaccines will apply only to target population <15 year of age. For the second population group (those infected with HPV), patients will also need to be screened, diagnosed, treated and/or monitored after treatment for a period of 15 to 25 years (from age 18 to age 40/45). During this period, the CD-Ratiometer can provide an efficient, cost effective, screening tool with all the advantages of Molecular Optical Biopsy (no need to remove tissue, real-time results, and high accuracy). Significant competitive approaches to cancer screening include, X-ray, CT, ultrasound, magnetic resonance and radionuclide imaging technologies; all based on the detection of intra-tissue structural abnormalities and are not suited to the evaluation of tissue surface lesions. Our proprietary IP represents a new diagnostic paradigm. It offers the promise of providing a more cost effective and user friendly screening procedure with increased sensitivity and specificity, and ultimately, of replacing excision biopsy as the diagnostic gold standard. We believe that we have strong intellectual property position that will permit us to achieve a strong position in this new area; competition from both new and established firms, continues to be intense. Many of these firms have greater resources than registrant and more experience in the field of cancer diagnostics. Finally, there can be no assurances that the Mediscience Technology, even if developed successfully, will be accepted commercially in the marketplace in any application format. The competitors in the optical biopsy pill market today offer a product supported by a different technical platform and with inherently different capabilities. Photonic Pill (CPE) Given's PillCam involves recorded white-light optical imaging and analysis, Olympus Optical LTD's EndoCapsule involves real-time white-light optical imaging, transmission and analysis, and SmartPill's involves chemical analysis of tissue, Registrant/Info tonics Pill (CPE) utilizes molecular autoflourecsence sensing The four scientific platforms upon which pill technology is being produced use micro-electromechanical and micro-optic-electro-mechanical systems technology combining the features of remote operation with MEMS and MOEMS technology and in vivo imaging, (GIVEN-OLYMPUS) or in, chemical analysis (SMARTPILL), or in the use of autoflourecsence data (MEDISCIENCE). Scientists are able to create in vivo systems that can collect large quantities of data and transmit that data to external systems while the device remains in vivo to enable doctors to navigate through the body to collect visual chemical or photonic data. The expectation is that such developments will allow doctors to generate new tests and - 7 - better analyze and diagnose disease in the upper GI tract and other parts of the body through less invasive and disruptive methods for the patient. The efforts of Infotonics, in conjunction with Mediscience Technology Corp. and BioScopix Inc., to develop a photonics biopsy pill based on a photonics platform that utilizes the inherent molecular physical characteristics of normal, pre-cancerous, and cancerous tissues exhibit when illuminated with light of specific frequencies, registrant believes, represents the next step in diagnostic technology. INFOTONICS, This technology is based on registrants IP Platform and continued research at Infotonics. Registrant's photonics-based optical biopsy pill introduces a new and promising concept into the imaging pill market of molecular Optical Biopsy. Commercialization of the (CPE) requires the finalization of specific engineering and implementation decisions concerning the components and composition of the pill. Infotonics/Registrant's Optical Biopsy Pill has the capability of merging registrant's optical imaging techniques and nano-technology miniature-scaling. Such compact devices use three-dimensional mechanical components of various configurations on a miniaturized scale including an optical component, resulting in an ingestible Pill system. Registrant believes that its (CPE) would provide an additional functionality of actually possessing the ability to treat cancer through manipulation of ultra-violet and visible autoflourecsence by incorporating much of registrants underlying IP platform science of photonic cancer-detection. Dr. Alfano's research indicates that use of fluorescent light, excited photonic light, and varying spectroscopy techniques will aid in more quickly and accurately detecting and treating cancerous and pre-cancerous growths in vivo. Once completed, registrants (CPE) pill can offer doctors a new and valuable method of detecting cancerous and pre-cancerous cells in a way that addresses the concerns of the current marketplace. There is need for a device that is less invasive than the "Barium Swallow" without the risks and discomfort of the procedure. By finalizing this product, Registrant could become market leader by offering a competitive (CPE) design that physicians will embrace. Once the (CPE) is accepted by the medical industry, as is the Given Imaging Pill, insurance carriers will be more willing to cover its costs as re-imbursement. Infotonics, with the approval of registrant, commissioned Syracuse University Law to prepare an in depth analysis of the ingestible Pill market, the over-all business opportunity and an evaluation of the four participant technical platforms utilized in respective ingestible Pills. The report covered in depth registrants (CPE) effort utilizing photonics-based optical biopsy technology as its technology base. (See 8-K filing w/Syracuse Univ. 57 Pg. report exhibit May 26, 2006 o The report concludes that the Photonic Biopsy Pill demonstrates great promise in providing a non-invasive, preliminary means of detecting in vivo pre-cancerous and cancerous tissues in the upper digestive tract. o A number of important design issues remain to be addressed on the components and design of a miniaturized Photonic Biopsy Pill including the selection of a particular light emitter, light detector, power source, and position-detection system and casing design. o The Photonic Biopsy Pill has the potential to become a market leader in diagnostic technology, perhaps the industry standard, as a new diagnostic device that physicians will embrace because it addresses real concerns of the current marketplace. o The assessment process did not reveal any obvious IP barriers to commercializing the Photonic Biopsy Pill based on competitors' products in the market today. GIVEN IMAGING: PillCam(TM) Capsule Endoscope, approved by the FDA, a non-reusable capsule taken with water the same way an ordinary pill is taken. Capable of transmitting 50,000 color images to be reviewed for medical significance. The purpose is to process collected data and translate it into a video image of the small intestine. The Given system allows doctors to look at, alter, save, or e-mail the video, as well as save snapshots of the video or small video clips Given Diagnostic system is marketed in the United States as well as sixty other countries. Given Imaging, with a present $600 million market capitalization is a young and rapidly growing company. (See CITIGROUP/Smith Barney Analyst Report 10-1-2004 by Peter Bye. Page 20 "Registrant-Infotonics" identified as competitors). - 8 - OLYMPUS: camera pill is the ingestible EndoCapsule, available in Europe since October, with FDA approval pending in the United States. Like the Given product, the Olympus camera pill generates white light images of the digestive tract, providing an alternative to conventional white-light endoscopy. It transmits images via a "built-in capsule antenna," which is capable of transmitting to the data recorder at a rate of two images per second. SMARTPILL: ingestible capsule endoscopy provides data to a computer, which monitors the progress of the pill. It is not a camera pill at all, it does not produce a visual image rather it is a mechanism that uses sensors to record and transmit data regarding pressure and pH levels as it moves completely through the entire GI tract. Currently SmartPill is still a work in progress. Clinical trials for SmartPill began in March of 2005, and successfully completed the first phase of its clinical trials. Government Regulation (FDA) Matters The FDA classifies medical devices into one of three classes, Class I, II, or III. This classification is based on the controls deemed necessary by the FDA to reasonably insure the safety and effectiveness of the device. Class I devices are those whose safety and effectiveness can be reasonably ensured through the use of general controls, such as labeling, adherence to GMP requirements and the "510-(k)" process of marketing pre-notification. Class II devices are those whose safety and effectiveness can reasonably be ensured through implementation of general and special controls, such as performance standards, post market surveillance, patient registries, and FDA guidelines. Class III devices are those devices that must receive pre-market approval ("PMA") to insure their safety and effectiveness. They are generally life-sustaining, life-supporting, or implantable devices, and also include devices that are not substantially equivalent to a legally marketed Class I or II device or to a Class III device first marketed prior to May 28, 1976 for which a PMA has not yet been requested by the FDA. January 4, 2006 -Mediscience Technology Corp. through its New York subsidiary, Medi-Photonics Development LLC, formally filed with the FDA its documented request for a pivotal study commencement of its optical biopsy device, the CD-Ratiometer. The proposed indication for the use of the CD-Ratiometer is as a device that serving as an adjunct to diagnosis for cancer detection of the cervix and for other molecular physiological abnormalities. The (FDA) reviewed our submission proposing a protocol for a pilot study for the C-D Ratiometer entitled "A Multi-center Pilot study to establish the Safety and Parameters of Efficacy of an Optical Biopsy Device (CDR) for Cancer Detection of Cervix Preliminary to a Pivotal Study," and determined that our proposed clinical investigation is a non-significant risk (NSR) device study because it does not meet the definition of a significant risk (SR) device under the applicable FDA regulations (21 CFR 812,). An IDE application is not required to be submitted to, or approved by, FDA for a NSR study. A NSR study is, however, subject to the abbreviated requirements described in the IDE regulations. The sponsor of the investigation must properly label the device, obtain institutional review board approval of the investigation as a NSR study; ensure that each investigator obtains informed consent from each subject under the investigator's care; comply with the monitoring requirements; maintain required records; file the reports required; ensure that participating parties maintain required records and file all reports required. Registrant must also comply with the prohibitions against promotion and other practices as identified in ss. 812.7- According to this section of the regulation, the sponsor of a NSR study, investigator, or any person acting for or on behalf of the registrant or investigator, is prohibited from promoting or test marketing the investigational device until after FDA has approved the device for commercial distribution; commercializing the device by charging a price greater them that necessary to recover the cost of manufacture, research, development, and handling; unduly prolonging the investigation; and representing the investigational device as being safe or effective for the purposes for which it is being investigated. Although registrant believes that our cancer diagnostic products will ultimately be approved, there is no assurance the FDA will act favorably or quickly in making such reviews and approving our products for sale. We may encounter delays or unanticipated costs in our efforts to secure needed funding and all governmental approvals or licenses, which could delay or possibly preclude us from completing our FDA process and/or marketing our CD products. To the extent that we intend to market our CD products in foreign markets through BioScopix Inc or others, we will be subject to foreign governmental regulations, as well as USA, with respect to the manufacture and - 9 - sale of our medical device products. We cannot accurately estimate the cost and time that will be required in order to comply with such regulations. Patents and Proprietary Rights April 14, 2003 registrant secured the exclusive world-wide license for US patent "Stokes-Shift Fluorescence Spectroscopy for Detection of Disease and Physiological State of Specimen". The patent was filed under the Patent Cooperation Treaty ("PCT") (1970) for EU approval on January 23, 2004 and continues in that process. October 18, 2005 registrant agreed to secure the exclusive world-wide license rights for US patent disclosure US 60/725,670 "Phosphorescence and Fluorescence Spectroscopy for Detection of Cancer and Pre-Cancer from Normal/Benign regions" from RFCUNY. Dr. Robert Alfano and registrant believe that all recent filings plus registrants achieved IP claims in totality inter-relate in the process of non-invasively detecting cancerous tissue within the body and on issuance would extend the Company's core IP technology 17+ yrs expanding, maintaining and continuing registrants IP position in the Optical Biopsy field. Registrant regards this accumulated and related patent cluster as pioneering, blocking and seminal in its area of cancer and physiological change diagnosis both in-vivo and in-vitro. (See Patent list infra.) EU Patent Cooperation Treaty: Registrant is seeking patent protection simultaneously in each of a large number of western European countries by filing an "international" patent application. The application is subjected to an "international search. The search results in an "international search report," a listing of the citations of such published documents that might affect the patentability of the invention claimed in the application. The ISA also prepares a written opinion on patentability. The report and the written opinion are communicated to the applicant for his decision to continue or not in the process. The medical device industry places considerable importance on obtaining patent protection and protecting trade secrets for new technologies, products, and processes because of the substantial length of time and expense associated with bringing new products through development and regulatory approval to the marketplace. Accordingly, the Company or the Research Foundation of CUNY files patent applications to protect technologies that the Company believes are significant to the development of the Company's business. The Company either owns or holds exclusive licenses to 28 U.S. patents, plus 1 in Japan, for a total of 29. There can be no assurance, however, that any pending patent applications will issue as patents, or if patents do issue, that the claims will be sufficiently broad to protect what the Company believes to be its proprietary rights. In addition, there can be no assurance that issued patents or pending patent applications will not be challenged or circumvented by competitors, or that the rights granted there-under will provide competitive advantage to the Company. The Company also relies on trade secrets and know-how that it seeks to protect in part, through the use of Confidentiality Agreements. There can be no assurance that these agreements will not be breached, that the Company will have adequate remedies for any breach, or that the Company's trade secrets and know-how will not otherwise become known to or independently developed by competitors. Third Party Reimbursement Registrant ultimately will seek reimbursement from third-party payers, primarily in the United States through Federal, State, Medicare, Medicaid and private health insurance plans, and in other countries, typically national government sponsored health and welfare plans. Such reimbursement will be subject to the regulations and policies of governmental agencies and other third-party payers. Reduced governmental expenditures in the United States and in other countries continue to put pressure on diagnostic procedure reimbursement. The Company cannot predict what, if any changes, may be forthcoming in these policies and procedures, nor the effect of such changes on our business potential of our screening and diagnostic technology in any endoscopic format (CD-R, ingestible CPE Pill) - 10 - Other Technologies and other applications In addition to our developments in native tissue fluorescence spectroscopy we have also invented certain other potentially useful diagnostic optical imaging technology. The optical imaging technology uses laser light to image dense tissues by capturing the early photons of light shown through the imaged tissue and gating off the scattered, later arriving light, which reduces the interference and results in clearer images than can be traditionally be seen using currently available optical imaging technologies, such as, computed tomography scanning or x-rays or mammograms. Our Patents Registrants independently owned and inter-related IP patent cluster acquired through contract with the Research Foundation City University of New York (RFCUNY), see 8-K filed June 1, 2002, Attachment "A" MTC Licensed/Funded Patents: ATTACHMENT "A" Medical Diagnostic Optical Technology US Patent application US 60/725,670 "Phosphorescence and Fluorescence Spectroscopy for Detection of Cancer and Pre-Cancer from Normal/Benign regions" # 7,192,783 March 20,2007 US Patent issued "Stokes-Shift Fluorescence spectroscopy for detection of disease and physiological state of specimen". #5,042,494,August 27, 1991, Method and Apparatus for Detecting Cancerous Tissue using Luminescence Excitation Spectra, R. R. Alfano. #5,131,398, July 21, 1992, Method and Apparatus for Distinguishing Cancerous Tissue from Benign Tumor Tissue, Benign Tissue or Normal Tissue using Native Fluorescence, R. R. Alfano, B. Das, G. Tang. #5,261,410, November 16, 1993, Method for determining if a Tissue is a Malignant Tumor Tissue, a Benign Tumor Tissue, or a Normal Benign Tissue using Raman Spectroscopy, R. R. Alfano, C. H. Liu, W. S. Glassman. #5,293,872, March 15, 1994, Method for Distinguishing between Calcified Atherosclerotic Tissue and Fibrous Atherosclerotic Tissue or Normal Cardiovascular Tissue Using Raman Spectroscopy, R. R. Alfano, C. H. Liu #5,348,018, September 20, 1994, Method for determining if Tissue is Malignant as opposed to Non-Malignant using Time-Resolved Fluorescence Spectroscopy, R. R. Alfano, A. Pradhan, G. C. Tang, L. Wang, Y. Budansky, B. B. Das. #5,413,108, May 9, 1995, Method and Apparatus for Mapping a Tissue Sample for and Distinguishing Different Regions thereof based on Luminescence Measurements of Cancer-indicative Native Fluorophor, R. R. Alfano. #5,467,767, November 21, 1995, Method for Determining if Tissue is Malignant as opposed to Non-Malignant using Time-resolved Fluorescence Spectroscopy, R. R. Alfano, Asima Pradhan, G. C. Tang, L. Wang, Y. Budansky, B. B. Das. #5,635,402, June 3, 1997. Technique for Determining whether a Cell is Malignant as opposed to Non-malignant using Extrinsic Fluorescence Spectroscopy, R. R. Alfano, Cheng H. Liu, Wei L. Sha, Yury Budansky. - 11 - #5,769,081, June 23, 1998, Method for Detecting Cancerous Tissue using Optical Spectroscopy and Fourier Analysis, R. R. Alfano, A. Katz, Y. Yang. #5,849,595, December 15, 1998, Method for Monitoring the Effects of Chemotherapeutic Agents on Neoplasmic Media, R. R. Alfano, G. C. Tang, S. P. Schantz. #5,983,125, November 9, 1999, Method and apparatus for in vivo examination of subcutaneous tissues inside an organ of a body using optical spectroscopy, R. R. Alfano, Y. Budansky. #6,006,001, December 21, 1999, Fiber optic assembly useful in optical spectroscopy, R. R. Alfano, S. Demos, G. Zhang. #6,080,584, June 27, 2000, Method and apparatus for detecting the presence of cancerous and precancerous cells in a smear using native fluorescence spectroscopy, Robert R. Alfano, Singaravelu Ganesan, and Yury Budansky. #6,091,985, July 18, 2000, Detection of cancer and precancerous conditions in tissues and/or cells using native fluorescence excitation spectroscopy, Robert R. Alfano, Singaravelu Ganesan, Alvin Katz, Yang Yuanlong. Optical Imaging for Medical Purposes US Patent Pending "Three-dimensional Radiative Transfer Tomography for Turbid Media." #5,371,368, December 6, 1994, Ultrafast Optical Imaging of Objects in a Scattering Medium, R. R. Alfano, P. P. Ho, L. Wang. #5,625,458, April 29, 1997, Method and System for Imaging Objects in Turbid Media using Diffusive Fermat Photons, R. R. Alfano, A. Y. Polishchuk. #5,644,429, July 1, 1997 (see #5,371,368), 2-Dimensional Imaging of Translucent Objects in Turbid Media, R. R. Alfano, P. P. Ho, X. Liang. #5,710,429, January 20, 1998, Ultrafast Optical Imaging of objects in or Behind Scattering Media, R. R. Alfano, Feng Liu, Q. Z. Wang P. Ho, L. M. Wang, X. Liang. #5,719,399, February 17, 1998, Imaging and Characterization of Tissue based upon the Preservation of Polarized Light transmitted therethrough, R. R. Alfano, S. G. Demos. #5,799,656, September 1, 1998, Optical Imaging of Breast Tissues to enable the Detection therein of Calcification Regions Suggestive of Cancer, R. R. Alfano, P. P. Ho, L. Wang, X. Liang, P. Galland. #5,813,988, September 29, 1998, Time Resolved Diffusion Tomographic Imaging in Highly Scattering Turbid Media, R. R. Alfano, W. Cai, F. Liu, M. Lax, Bidyut B. Das. #5,847,394, December 8, 1998, Imaging of Objects Based upon the Polarization or Depolarization of Light, R. R. Alfano, S. G. Demos. #5,931,789, August 3, 1999, Time-resolved diffusion tomographic 2D and 3D imaging in highly scattering turbid media, Robert R. Alfano, Wei Cai, Feng Liu, Melvin Lax. # 6,208,886 B1, March 27, 2001, Non-linear optical tomography of turbid media, Robert R. Alfano, Yici Guo, Feng Liu, Ping Pei Ho. # 6,215,587, April 10, 2001, Microscope imaging inside highly scattering media, Robert R. Alfano, Gordon Anderson, Feng Liu. - 12 - The Company and CUNY Research Foundation have been diligent in the payment of maintenance obligations to the US Patent Office during the life of each of the Company's significant patents. Employees As of February 28, 2007 the Company had one (1) full-time employee/s in its New York Subsidiary Medi-photonics LLC Peter Katevatis Chairman CEO, one (1) retained consultant/s, Dr. Robert R. Alfano and one part-time employee Frank Benick CFO As of February 28, 2006 the Company had two (one) full-time employee/s in its New York Subsidiary Medi-photonics LLC Michael Engelhart President COO, Peter Katevatis Chairman CEO, two (one) retained consultant/s, Dr. Robert R. Alfano and John Matheu and one part-time employee Frank Benick CFO Michael Engelharts three year employment agreement terminated April 23, 2006. (his employment contract is part of and an attachment to Registrants SEC 10-K 2003 page 44 "Employment contract and warrants Exhibits "A","B","C" herein incorporated by reference. See subsequent events Item 14 John Matheu one year consulting agreement terminated April 6, 2006 by its terms. Neither the full or part-time employees nor the retained consultants are governed by any collective bargaining agreement; the relations between the Company and its present employees and retained consultants are believed to be satisfactory. Item 2. Description of Property Registrant is having on-going discussions with David Smith President of Infotonics Research, Rochester New York (CPE development partner and registrant shareholder) to establish a company incubation site for development, assembly and manufacturing capability on the New York State Infotonics Campus in Rochester NY. Properties: Our corporate headquarters are located in Cherry Hill, New Jersey. We have a month-to-month lease dated July 25, 2002 with Mr. Katevatis, our Chairman and Chief Executive Officer, for use of approximately 3,000 square feet of office space, pursuant to which we pay no rent but have assumed the obligation to pay all taxes, maintenance, insurance, utilities and repairs relating to such premises. We believe that our current facilities adequately provide for our operations. Item 3. Legal Proceedings We are not presently a party to any pending litigation, nor, to the knowledge of our management, is any litigation threatened against us which may materially affect our operations or business. Item 4. Submission of Matters To A Vote Of Security Holders None. PART II Item 5. Market for Common Equity and Related Stockholder Matters Market Information The Company's Common Stock is traded on the over-the-counter market under the symbol "MDSC." The following table sets forth the range of high and low bid quotations of the Company's Common Stock for the periods set forth below, as reported by the National Association of Securities Dealers, Inc. and Silicon Investors Historical data. Such quotations represent inter-dealer quotations, without adjustment for retail markets, markdowns or commissions, and do not necessarily represent actual transactions. - 13 - Holders As of February 28, 2007, the approximate number of all holders of record of the Company's Common Stock 735 and Series A Preferred Stock -0- Dividends The Company has not paid or declared any dividends on its Common Stock since its inception, and intends to reinvest earnings, if any, in the Company to accelerate its growth. Accordingly, the Company does not contemplate or anticipate paying any dividends upon its Common Stock in the foreseeable future. Item 6. Management's Discussion and Analysis The following discussion should be read in conjunction with the Financial Statements and the notes thereto that appear in Item 7 of this annual report on Form 10-KSB. Critical Accounting Policies & Estimates Our consolidated financial statements are prepared in conformity with accounting principles generally accepted in the United States of America. Note 1 to the consolidated financial statements describes the significant accounting policies and methods used in the preparation of our consolidated financial statements. We have identified the policies below as some of the more critical to our business and the understanding of our results of operations. These policies may involve a higher degree of judgment and complexity in their application and represent the critical accounting policies used in the preparation of our financial statements. Although we believe our judgments and estimates are appropriate and correct, actual future results may differ from our estimates. If different assumptions or conditions were to prevail; the results could be materially different from our reported results. The impact and any associated risks related to these policies on our business operations is discussed throughout Management's Discussion and Analysis of Financial Condition and Results of Operations where such policies affect our reported and expected financial results. Use of Estimates The preparation of our consolidated financial statements, in conformity with accounting principles generally accepted in the United States, requires management to make estimates and assumptions that affect the reported amounts of assets, liabilities and equity and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. These estimates have a material impact on our financial statements, and are discussed in detail throughout our analysis of the results of operations. In addition to evaluating estimates relating to the items discussed above, we also consider other estimates, including, but not limited to, Patent licenses and their related costs including the maintenance of Patents licenses and all costs incurred in connection with acquiring patents, patent licenses and other proprietary rights related to our commercially developed products, income taxes, and financing operations. We base our estimates on historical experience and on various other assumptions that are believed to be reasonable under the circumstances, the results of which form the basis for making judgments about the carrying value of assets, liabilities and equity that are not readily apparent from other sources. Actual results could differ from those estimates under different assumptions or conditions. Additional information regarding risk factors that may impact our estimates is included below under "Risk Factors." - 14 - Income Taxes As part of the process of preparing our consolidated financial statements we are required to estimate our income taxes in each of the jurisdictions in which we operate. This process involves us estimating our actual current tax expense together with assessing temporary differences resulting from differing treatment of items, for tax and accounting purposes. These differences result in deferred tax assets and liabilities, which are included within our consolidated balance sheet. We must then assess the likelihood that our deferred tax assets will be recovered from future taxable income and to the extent we believe that recovery is not likely, we must establish a valuation allowance. In the event that we determine that we would be able to realize deferred tax assets in the future in excess of the net recorded amount, an adjustment to the deferred tax asset would increase income in the period such determination was made. Significant management judgment is required in determining the valuation allowance recorded against our net deferred tax assets, which consist of net operating loss carry forwards. We have recorded a valuation allowance of $5.9 million as of February 28, 2006, due to uncertainties related to our ability to utilize our deferred tax assets before they expire. The valuation allowance is based on our estimates of taxable income by jurisdiction in which we operate and the period over which our deferred tax assets will be recoverable. Fiscal Years Ended February 28, 2007 and 2006 Revenues We had no revenues during the year ending February 28, 2007 and February 28, 2006. Our primary focus was our continued development of our light-based technology. General and Administrative Expense General and administrative expenses decreased approximately $734,000 or 39% during the current year ended February 28, 2007 as compared to the year ended February 28, 2006. This decrease is net of both increases and decreases in key general and administrative expense categories. Included in the decrease in general and administrative expenses is a decrease in consulting costs, approximating $518,000 during the current year when compared to the prior year. The decrease was partly comprised of approximately $381,000 of deferred costs amortized as an expense, as compared to approximately $795,000 of deferred costs amortized as an expense in the previous year, resulting in a decrease of $414,000. The overall decrease in consulting costs was complimented by a decrease of $12,500 in other consulting costs expended, all associated with corporate management, investor relations, marketing opportunities, product development and corporate funding. Advertising, travel and marketing decreased approximately $29,000 in the current year when compared to the prior year. In the prior year, the Company was very active in pursuing the establishment of copromotional arrangements for the marketing, distributing, and commercial exploitation of cancer detection technology, along with the promotional activities of raising capital to support these objectives. Included in the decrease in general and administrative expenses is a decrease in professional fees approximating $38,000 during the current year when compared to the prior year. In the prior year, the Company had incurred additional professional fee costs associated with a Securities and Exchange Commission Filing and had previously employed an accounting consultant which subsequently became employed as the Chief Financial Officer. Also included in the decrease in general and administrative expense is a decrease in salaries, wages and related costs approximating $88,000 during the current year when compared to the prior year. The decrease in payroll costs was net of an increase of $35,500 of payroll costs associated with the employment of the Chief Financial Officer, who was previously employed as an accounting consultant. All other general and administrative expenses decreased approximately $61,000 during the current year when compared to the prior year. The largest item of decline within the other general and administrative expense category was rent expense for an office in New York ($7,700). Research and Development Expense Research and development expense decreased approximately $61,000 during the current year ended February 28, 2007 when compared to the prior year ended February 28, 2006. This decrease was comprised of net - 15 - increases and decreases in several key research and development categories. Included in the increase was approximately $15,000 in payment, both associated with the Company's agreement with Alfanix Technology to construct sophisticated photonics devices for cancer diagnostics and to introduce the devices in Latin America for testing on human subjects. Also included in the increase was $30,000 in payments to Infotonics for preliminary work in conjunction with the development of the Compact Pill Explorer (CPE). The decrease was partly comprised of approximately $177,000 of deferred costs amortized as an expense, as compared to approximately $151,000 amortized in the previous year, resulting in a decrease of $27,000. Also included in the decrease was approximately $133,000 in payments made to Research Foundation of the City University of New York. Liquidity and Capital Resources We had a deficiency in working capital as of February 28, 2007 of approximately $3,404,000 compared to a deficiency of approximately $3,012,000 at February 28, 2006 or an increase in the deficiency of approximately $392,000 for the current year ended February 28, 2007. The increase in the deficiency was comprised of an increase of approximately $24,000 in current assets and a decrease of approximately $415,000 in current liabilities which is primarily composed of accrued liabilities. The deficiency in working capital is primarily represented by accruals for professional fees, consulting, salaries, and wages and other general obligations. Cash flows from financing activities was $425,000 for the year ended February 28, 2007, primarily related to the proceeds from the private placement of common stock. The proceeds from the private placement will be primarily used for working capital and clinical development of certain prototypes, regulators, medical and scientific affairs, and market research. Our ability to continue our operations is largely dependent upon obtaining regulatory approval for the commercialization of our cancer detection technology. There can be no assurance as to whether or when the various requisite government approvals will be obtained or the terms or scope of these approvals, if granted. We intend to defray the costs of obtaining regulatory approval for the commercialization of such technology by the establishment of clinical trial arrangements with medical institutions. We intend to continue to pursue the establishment of co-promotional arrangements for the marketing, distribution and commercial exploitation of its cancer detection technology. Such arrangements, if established, may include up-front payments, sharing of sales revenues after deduction of certain expenses, and/or product development funding. Our management anticipates that substantial resources will be committed to a continuation of our research and development efforts and to finance government regulatory applications. While management believes that we will obtain sufficient funds to satisfy our liquidity and capital resources needs for the short term from the private placement of our securities and short term borrowings, no assurances can be given that additional funding or capital from other sources, such as copromotion arrangements, will be obtained on a satisfactory basis, if at all. In the absence of the availability of financing on a timely basis, we may be forced to materially curtail or cease our operations. Our operating and capital requirements, as described above, may change depending upon several factors, including: (i) results of research and development activities; (ii) competitive and technological developments; (iii) the timing and cost of obtaining required regulatory approvals for our products; (iv) the amount of resources which we devote to clinical evaluation and the establishment of marketing and sales capabilities; and (v) our success in entering into, and cash flows derived from, co -promotion arrangements. Off-Balance Sheet Arrangements We have no off-balance sheet arrangements that have or are reasonably likely to have a current or future effect on the small business issuer's financial condition, changes in financial condition, revenues or expenses, results of operations, liquidity, capital expenditures or capital resources that is material to investors. RISK FACTORS The following risk factors should be considered carefully in addition to the other information presented in this report. This report contains forward looking statements that involve risks and uncertainties. Our actual results may differ significantly from the results discussed in the forward looking statements. Factors that might cause such differences include, but are not limited to, the following: - 16 - We do not have a long operating history, which makes it difficult for you to evaluate our business. Because limited historical information is available on our revenue trends and operations, it will be difficult for you to evaluate our business. Our prospects must be considered in light of the substantial risks, expenses, uncertainties and difficulties encountered by entrants into the medical device industry, which is characterized by increasing intense competition and a high failure rate. We have a history of losses, and we expect losses to continue. We have never been profitable, and we have had operating losses since our inception. We expect our operating losses to continue as we continue to expend substantial resources to launch our product line, to complete development of our products, obtain regulatory clearances or approvals, and build our marketing, sales, manufacturing and finance organizations, and conduct further research and development. To date, we have been engaged primarily in research and development efforts. The further development and commercialization of our products will require substantial development, regulatory, sales and marketing, manufacturing and other expenditures. If we cannot obtain additional funds when needed, we will not be able to implement our business plan. We will require substantial additional capital to develop our products, including completing product testing and clinical trials, (pilot and Pivital) obtaining all required regulatory approvals and clearances, beginning and scaling up manufacturing, and marketing our products. We have historically funded a significant portion of our activities through private placements and available University matching funds. We are seeking a collaborative partner for our technology and are seeking targeted funding for our FDA approved March 29, 2006 cervical cancer (Pap) program. Any failure to find collaborative partners to fund our capital expenditures, or our inability to obtain capital through other sources, would limit our ability to grow and operate as planned. Even if we do enter into an agreement with a collaborative partner, the obligations of a collaborative partner to fund our expenditures is largely discretionary and depends on a number of factors, including our ability to meet specified milestones in the development and testing of the relevant product. We may not be able to meet these milestones, or our collaborative partner may not continue to fund our expenditures. We bear responsibility for all aspects of our Optical Biopsy platform product line and our cervical cancer CD-R and Compact Photonic ingestible Pill product, (developed with a collaborative equity partner Infotonics research). We may be required to raise additional funds through public or private financing, additional collaborative relationships or other arrangements. We believe that our existing capital resources may not be sufficient to fund our operations to the point of commercial introduction of our monitoring products, our cervical cancer detection products. . Any failure to achieve adequate funding in a timely fashion would delay our development programs and could lead to abandonment of one or more of our development initiatives. Any required additional funding may not be available on terms attractive to us, or at all. To the extent we cannot obtain additional funding, our ability to continue to develop and introduce products to market will be limited. Any additional equity financing will be dilutive to stockholders, and debt financing, if available, may involve restrictive covenants that would limit how we conduct our business or finance our operations. If we cannot obtain additional funds when needed, or achieve profitability we may not be able to continue as a going concern. Our independent auditors have included an explanatory paragraph in their audit report referring to our recurring operating losses and a substantial doubt about our ability to continue as a going concern. Absent additional funding from private or public equity or debt financings, collaborative or other partnering arrangements, or other sources and If we do not secure additional funding, we will be unable to conduct all of our product development efforts as planned, and we may need to cease operations or sell assets. In addition, the existence of the explanatory paragraph in the audit report may in and of itself cause our stock price to decline as certain investors may be restricted or precluded from investing in companies that have received this notice in an audit report. Our ability to sell our products is controlled by government regulations, and we may not be able to obtain any necessary clearances or approvals. The design, manufacturing, labeling, distribution and marketing of medical device products are subject to extensive and rigorous government regulation including but not limited to FDA which can be expensive and uncertain and can cause lengthy delays before we can begin selling our products. - 17 - In the united states, the Food and Drug Administration's actions could delay or prevent our ability to sell our products, which would adversely affect our growth and strategy plans. In order for us to market our products in the United States, we must obtain continued clearance or approval from the Food and Drug Administration. We cannot be sure: that we or any collaborative partners will make timely filings with the FDA; that the FDA will act favorably or quickly on these submissions; that we will not be required to submit additional information or perform additional clinical studies; that we would not be required to submit an application for PMA as described below; or that other significant difficulties and costs will not be encountered to obtain FDA clearance or approval. The pre-market approval process is more rigorous and lengthier than the 510(k) clearance process for pre-market notifications; it can take several years from initial filing and require the submission of extensive supporting data and clinical information clinical study data. The FDA may impose strict labeling or other requirements as a condition of its clearance or approval, any of which could limit our ability to market our products. Further, if we wish to modify a product after FDA clearance of a pre-market notification or approval of a pre-market approval application, including changes in indications or other modifications that could affect safety and efficacy, additional clearances or approvals will be required from the FDA. Any request by the FDA for additional data, or any requirement by the FDA that we conduct additional clinical studies or submit to the more rigorous and lengthier pre-market approval process, could result in a significant delay in bringing our products to market and substantial additional research and other expenditures. Similarly, any labeling or other conditions or restrictions imposed by the FDA on the marketing of our products could hinder our ability to effectively market our products. Any of the above actions by the FDA could delay or prevent altogether our ability to market and distribute our products. Further, there may be new FDA policies or changes in FDA policies that could be adverse to us. In foreign countries, including Latin American and European countries, we are also subject to government regulation, which could delay or prevent our ability to sell our products in those jurisdictions. In order for us to market our products in Latin America or Europe and some other international jurisdictions, we and our distributors and agents e.g. ALFANIX LTD must obtain required regulatory registrations or approvals. We must also comply with extensive regulations regarding safety, efficacy and quality in those jurisdictions. We may not be able to obtain the required regulatory registrations or approvals, or we may be required to incur significant costs in obtaining or maintaining any regulatory registrations or approvals we receive. Delays in obtaining any registrations or approvals required to market our products, failure to receive these registrations or approvals, or future loss of previously obtained registrations or approvals would limit our ability to sell our products internationally. For example, international regulatory bodies have adopted various regulations governing product standards, packaging requirements, labeling requirements, import restrictions, tariff regulations, duties and tax requirements. These regulations vary from country to country. For example In order to sell our products in Europe, we must maintain ISO 9001 certification and CE mark certification, which is an international symbol of quality and compliance with applicable European medical device directives. Failure to receive or maintain ISO 9001 certification or CE mark certification or other international regulatory approvals would prevent us from selling in Europe and similar requirements would prevent us from selling in Latin American countries. Even if we obtain clearance or approval to sell our products, we are subject to ongoing requirements and inspections that could lead to the restriction, suspension or revocation of our clearance. We, as well as any collaborative partners, will be required to adhere to applicable FDA regulations regarding good manufacturing practice, which include testing, control, and documentation requirements. We are subject to similar regulations in foreign countries. Ongoing compliance with good manufacturing practice and other applicable regulatory requirements will be strictly enforced in the United States through periodic inspections by state and federal agencies, including the FDA, and in international jurisdictions by comparable agencies. Failure to comply with these regulatory requirements could result in, among other things, warning letters, fines, injunctions, civil penalties, recall or seizure of products, total or partial suspension of production, failure to obtain pre-market clearance or pre-market approval for devices, withdrawal of approvals previously obtained, and criminal prosecution. The restriction, suspension or revocation of regulatory approvals or any other failure to comply with regulatory requirements would limit our ability to operate and could increase our costs. Our success largely depends on our ability to obtain and protect the proprietary information on which we base our products. Our success depends in large part upon our ability to establish and maintain the proprietary nature of our technology through the patent process, as well as our ability to possibly license from others - 18 - patents and patent applications necessary to develop products. If any of our patents are successfully challenged, invalidated or circumvented, or our right or ability to manufacture our products were to be limited, our ability to continue to manufacture and market our products could be adversely affected. In addition to patents, we rely on trade secrets and proprietary know-how, which we seek to protect, in part, through confidentiality and proprietary information agreements. The other parties to these agreements may breach these provisions, and we may not have adequate remedies for any breach. Additionally, our trade secrets could otherwise become known to or be independently developed by competitors. We have been issued, or have rights to, 28 U.S. patents (including those under license). In addition, we have filed for, or have rights to, U.S. patents (including those under license) that are still pending. One or more of the patents we hold directly or license from third parties, may be successfully challenged, invalidated or circumvented, or we may otherwise be unable to rely on these patents. We have contract obligations to financially maintain these patents with periodic payments to the US, Japan and EU patent offices which could be unmet jeopardizing our existing rights. These risks are also present for the process we use or will use for manufacturing our products. In addition, our competitors, many of whom have substantial resources and have made substantial investments in competing technologies, may apply for and obtain patents that prevent, limit or interfere with our ability to make, use and sell our products, either in the United States or in international markets. The medical device industry has been characterized by extensive litigation regarding patents and other intellectual property rights. In addition, the United States Patent and Trademark Office may institute interference proceedings. The defense and prosecution of intellectual property suits, Patent and Trademark Office proceedings and related legal and administrative proceedings are both costly and time consuming. Moreover, we may need to litigate to enforce our patents, to protect our trade secrets or know-how, or to determine the enforceability, scope and validity of the proprietary rights of others. Any litigation or interference proceedings involving us may require us to incur substantial legal and other fees and expenses and may require some of our employees to devote all or a substantial portion of their time to the proceedings. An adverse determination in the proceedings could subject us to significant liabilities to third parties, require us to seek licenses from third parties or prevent us from selling our products in some or all markets. We may not be able to reach a satisfactory settlement of any dispute by licensing necessary patents or other intellectual property. Even if we reached a settlement, the settlement process may be expensive and time consuming, and the terms of the settlement may require us to pay substantial royalties. An adverse determination in a judicial or administrative proceeding or the failure to obtain a necessary license could prevent us from manufacturing and selling our products. We are developing our current product line independently from any collaborative partners, which may require us to access additional capital and to develop additional skills to produce, market and distribute these products. We are also currently seeking direct funding for and expect to commercialize our cervical cancer detection products independently of any collaborative partner. These activities require additional resources and capital that we will need to secure. There is no assurance that we will be able to raise sufficient capital or attract and retain skilled personnel to enable us to finish development, launch and market these products. Thus, there can be no assurance that we will be able to commercialize all, or any. Because our products, which use different technology or apply technology in more innovative ways than other medical devices, are or will be new to the market, we may not be successful in launching our products and our operations and growth would be adversely affected. Our products are based on new methods of cervical cancer detection. If our products do not achieve significant market acceptance, our sales will be limited and our financial condition may suffer. Physicians and individuals may not recommend or use our products unless they determine that these products are an attractive alternative to current tests that have a long history of safe and effective use. To date, our products have been used by only a limited number of people, and few independent studies regarding our products have been published. The lack of independent studies limits the ability of doctors or consumers to compare our products to conventional products. If we are unable to compete effectively in the highly competitive medical device industry, our future growth and operating results will suffer. The medical device industry in general and the markets in which we expect to offer products in particular, are intensely competitive. Many of our competitors have substantially greater financial, research, technical, and manufacturing, marketing and distribution resources than we do and have greater name recognition and lengthier operating histories in the health care industry. We may not be able to effectively - 19 - compete against these and other competitors. Further, if our products are not available at competitive prices, health care administrators who are subject to increasing pressures to reduce costs may not elect to purchase them. Accordingly, competition in this area is expected to increase. Furthermore, our competitors may succeed in developing, either before or after the development and commercialization of our products, devices and technologies that permit more efficient, less expensive non-invasive and less invasive monitoring, or cancer detection. It is also possible that one or more pharmaceutical or other health care companies will develop therapeutic drugs, treatments or other products that will substantially render our products obsolete. We have little manufacturing experience, which could limit our growth. We do not have manufacturing experience that would enable us to make products in the volumes that would be necessary for us to achieve significant commercial sales, and we rely upon our suppliers. In addition, we may not be able to establish and maintain reliable, efficient, full scale manufacturing at commercially reasonable costs, in a timely fashion. Difficulties we encounter in manufacturing scale-up, or our failure to implement and maintain our manufacturing facilities in accordance with good manufacturing practice regulations, international quality standards or other regulatory requirements, could result in a delay or termination of production. The availability of third-party reimbursement for our products is uncertain, which may limit consumer use and the market for our products. In the United States and elsewhere, sales of medical products are dependent, in part, on the ability of consumers of these products to obtain reimbursement for all or a portion of their cost from third-party payers, such as government and private insurance plans. Any inability of patients, hospitals, physicians and other users of our products to obtain sufficient reimbursement from third-party payers for our products, or adverse changes in relevant governmental policies or the policies of private third-party payers regarding reimbursement for these products, could limit our ability to sell our products on a competitive basis. We are unable to predict what changes will be made in the reimbursement methods used by third-party health care payers. Moreover, third-party payers are increasingly challenging the prices charged for medical products and services, and some health care providers are gradually adopting a managed care system in which the providers contract to provide comprehensive health care services for a fixed cost per person. Patients, hospitals and physicians may not be able to justify the use of our products by the attendant cost savings and clinical benefits that we believe will be derived from the use of our products, and therefore may not be able to obtain third-party reimbursement. Reimbursement and health care payment systems in international markets vary significantly by country and include both government sponsored health care and private insurance. We may not be able to obtain approvals for reimbursement from these international third-party payers in a timely manner, if at all. Any failure to receive international reimbursement approvals could have an adverse effect on market acceptance of our products in the international markets in which approvals are sought. Our success depends on our ability to attract and retain scientific, technical, managerial and finance personnel. Our ability to operate successfully and manage our future growth depends in significant part upon the continued service of key scientific, technical and managerial and finance personnel, as well as our ability to attract and retain additional highly qualified personnel in these fields. We may not be able to attract and retain key employees when necessary, which would limit our operations and growth. We are significantly influenced by our directors, executive officers and their affiliated entities. Our directors, executive officers and entities affiliated with them beneficially owned an aggregate of 21.1 % of our outstanding common stock as of February 28, 2006. Additionally Founders Katevatis and Alfano have historical and board approved anti-dilution rights of 17% and 4% respectively. The founders are owed significant non-interest bearing debt which they have the right to assign at any time or conversely convert upon 60 days notice to the board at $.25 cents per share. These stockholders, acting together, would be able to exert significant influence on substantially all matters requiring approval by our stockholders, including the election of directors and the approval of mergers and other business combination transactions. Item 7. Financial Statements The information that appears following Item 14 of this report and is incorporated herein by reference. - 20 - Item 8. Changes in and Disagreements with Accountants on Accounting and Financial Disclosure None. Item 8A. Controls and Procedures Evaluation of disclosure controls and procedures. Our Chief Executive Officer and principle financial officer evaluated the effectiveness of the Company's disclosure controls and procedures as of the end of the period covered by this report. Based on that evaluation, the Chief Executive Officer and principle financial officer concluded that our disclosure controls and procedures as of the end of the period covered by this report are functioning effectively to provide reasonable assurance that the information required to be disclosed by the Company in reports filed under the Securities Exchange Act of 1934 is recorded, processed, summarized and reported within the time periods specified in the Securities and Exchange Commission's rules and forms. A controlled system, no matter how well designed and operated, cannot provide absolute assurance that the objectives of the controls are met, and no evaluation of controls can provide absolute assurance that all control issues and instances of fraud, if any, within a company have been detected. Changes in internal control over financial reporting. No change in the Company's internal control over financial reporting occurred during the Company's most recent fiscal quarter that has materially affected, or is reasonably likely to materially affect, the Company's internal control over financial reporting. MEDISCIENCE TECHNOLOGY CORP. STRUCTURES AND GOVERNANCE PROCEDURES Over the past few years, new legal and regulatory requirements have caused corporations to adopt many new governance practices and to formalize previously informal practices. In developing and refining our practices during this period, we have been fortunate to build on a history of strong governance. We have sought not only to comply with new requirements, but to adopt best practices ensuring that we maintain the highest standards of ethics while building value for all of our stakeholders. The information, documents and policies described in the Corporate Governance area of our Web site MEDISCIENCETECH.com represent both the key components of our corporate governance and the result of our continuing attention to governance matters. Those components include: o All Board Committees o Corporate Governance Guidelines o Code of Ethics o EDGAR Filings o Governance and policy Executive Officers, The Board/Committee Accountability, Audit and Internal Control Framework Executive officers: The Chief Executive of Mediscience Technology Corp. and other senior executives are responsible for the day-to-day management of the Company. The Executive Committee which comprises the executive directors and certain other senior executives of MTC (the 'Executive Officers'), assists the Chief Executive in the management of the business. The following are Executive Officers of MTC and all, are members of the executive committee: John Kennedy, Peter Katevatis Esq., Michael Kouvatas Esq. - 21 - Board/Committees/Corporate Governance Registrant within the provisions of Sarbanes-Oxley Act is a Non-Accelerated SEC filer. As such, for fiscal years beginning on or after December 16, 2006 registrant must comply with S404 of the Sarbanes-Oxley Act of 2002. Management is required to report on the Group's internal controls over financial reporting. Work has been carried out during 2004 and 2005 in preparation for reporting in accordance with the Act and will continue to be progressed during the year e.g. retention of CFO Frank Benick CPA The Board is committed to the highest standards of Corporate Governance and considers that it has complied with the new Sarbanes Code throughout this year. Its Audit Committee has the skills and experience of corporate financial matters to discharge properly its responsibilities. Members John Kennedy Chairman, Michael Kouvatas Esq. and William Armstrong (directors) satisfy the definition of 'financial expert' in the Sarbanes-Oxley Act. Corporate Governance policies and procedures applied The Company's Shares are listed on the NASDAQ BB OTC and the Company is therefore subject to the rules of the NASADAQ as well as the US securities laws and the rules of the US Securities and Exchange Commission ("SEC" as applicable.) . The Board believes that it has complied throughout the year with both SEC and NASDAQ BB requirements related to corporate governance, with the exception that, our Executive Board committee does not consist wholly of independent directors. Registrant has recently applied for listing on the new proposed NASDAQ OTC tiered framework as a company fully in compliance with Sarbanes but trading under $1.00 The Board: The Board of Directors of MTC consists of an non-independent Chairman/CEO, Peter Katevatis and 4 directors. The meetings of the Board and the various committees are described specifically infra. Board management has a formal schedule of matters reserved for its decisions which include the approval of certain policies, budgets, financing plans, large capital expenditure projects, acquisitions, divestments and treasury arrangements and traditionally delegates specific responsibilities to counsel, Board Committees and/or board members. It reviews key activities of the businesses and considers and reviews the work undertaken by the Committees and/or board members. The board is charged with evaluating the performance of registrants executives performance. Board meetings are held to enable directors to have a greater understanding of the business and to query the management. D&O questionnaires are distributed each year to be executed and sworn to by each director for use by registrant internally and in audits as a requirement of corporate due diligence. All fully participating and available directors have full and timely access to all relevant information and, if necessary, to independent professional advice. Legal updates relevant to Mediscience corporate issues is periodically distributed and put into board minutes by inside counsel Peter Katevatis Esq., who is responsible to the Board for ensuring that Board legal procedures are complied with. There is a clear division of respective responsibilities which have been agreed by the Board. The Chairman's/CEO primary responsibility is for leading the Board, including ensuring its effectiveness and setting its agenda, supervising all other executive officers, whilst the Chief Operating Officer under the specific terms and conditions of his contract is responsible for managing the day-to-day business in accordance with the strategy, policies, budgets and business plans approved by the Board. The executive Board members stand ready to advise and assist in the management of the Company During fiscal year 2004, an informal periodic evaluation of the performance of the Board and its Committees was undertaken by its then auditor Parente Randolph LLP with the emphasis on registrants continuous improvement and effectiveness of corporate governance in compliance to Sarbanes-Oxley as a as a Non-Accelerated SEC filer. Suggestions were discussed by the audit committee in three separate meetings with the auditor and to the extent described here have been implemented. Each director was apprised and the suggestions presented to the whole Board with a number of recommendations acted upon. e.g. the retention of CFO Frank Benick on November 15, 2005 With the exception of Peter Katevatis Esq. Chairman CEO and outside counsel, John Matheu a contracted paid FDA consultant until April 6, 2006, Michael Engelhart Pres COO until April 23, 2006. None of the directors or their immediate families has ever had any direct relationship with registrant. - 22 - On review of D&O questionnaires submitted by complying directors, none either directly as an employee or as a partner, shareholder or officer of any organization that has a relationship with registrant have any relationship. No director of registrant is a director of a company or an affiliate in which any other director of MTC is a director. Directors to date do not receive remuneration and do not participate in registrants, pension plans, share option or performance related pay programs Details of MTC material service/consulting contracts and compensation payments are included herein either as narrative or as exhibits filed as part of the SEC SB-2 registration effective Jan. 12, 2005 (included herein in its totality by reference thereto) or if subsequent to January 12, 2005 have been filed with the SEC as exhibits, 8-K filings, Form 4's and related Form 5's. MTC By-laws: any director who has been appointed by the Board of Directors since the previous annual general meeting of shareholders, either to fill a casual vacancy or as an additional director, holds office only until the next annual general meeting and then is eligible for re-appointment by the shareholders. The directors are subject to removal with or without cause by the Board of Directors or the shareholders. The code of MTC business principles is available at MEDISCIENCETECH.com and is available on request, applies to all directors, officers and employees. Any breaches of the code are directed in writing to the Company Secretary who is obliged to raise the issue with the Board. During 2005 and up until February 28, 2006 there have been no breaches of the Code that have not been reported. No waivers have been put in place nor any amendments made to the Code. Board Committees: see infra and also found on MTC web site MEDISCIENCETECH.com. Audit Committee The Audit Committee met on 1 occasion in 2005 but has received and reviewed all 10-Q filings. (individual attendance is shown in parenthesis; The Committee, consisting entirely of independent non-executive directors, is chaired by John Kennedy (1). The other members of the Committee are Michael Kouvatas Esq. (1), William Armstrong (1) Mr Matheu was removed as an audit committee member upon entering into a paid consulting agreement with registrant April 6, 2005. The Committee met on 4 occasions in 2004 consisting entirely of independent non-executive directors, was chaired by John Kennedy (4). The other members of the Committee were John Matheu (4), William Armstrong (4). The Chairman of the Committee reports orally to the Board and minutes of the meetings are circulated to all members of the Board as reflected in MTC quarterly SEC 10-Q filings As a consequence of the preparatory work to satisfy and implement compliance within the provisions of the Sarbanes-Oxley Act, Management has identified certain internal control adjustments that were needed to effect reconciliations in prior years and has restated for these as disclosed in its SEC SB-2 registration filing with exhibits effective Jan. 12, 2005. These adjustments, when taken together, are indicators of a material weakness in the internal controls relating to US GAAS which management is in the process of re-mediating. In our opinion there have been no other changes in registrants internal control over financial reporting that occurred during the period covered by this 10-KSB Annual Report that has materially affected, or is reasonably likely to materially affect registrants internal control over financial reporting. The principal activities of the Audit Committee during the year ended February 28, 2006 include consideration of the reports on the quarterly reports, interim and annual accounts; Consideration of the proposed changes to US GAAS brought to the attention of the committee by auditors and CFO Frank Benick; The Audit Committee has responsibility for: Monitoring the integrity of the Company's accounts, ensuring that they meet statutory and associated legal and regulatory requirements and reviewing significant financial reporting judgments - 23 - contained; Monitoring announcements relating to the Company's financial performance; Monitoring and reviewing the effectiveness of the Company's internal audit function quarterly (10-Q) and annually (10-K); Making recommendations to the Board, regarding the appointment, re-appointment and removal of the external auditors, as appropriate; Approving the remuneration and terms of engagement of the external auditors; Monitoring and reviewing the external auditors' independence and the effectiveness of the audit process; developing policy for and pre-approval of the external auditors to supply non-audit services; Monitoring the effectiveness of internal financial controls; Reviewing the operation of the risk management process; and Reviewing arrangements by which staff may raise complaints against the Company regarding financial reporting or other matters. Code of Business Principles: The Board of Directors has adopted a Code of Ethics for all officers and directors which is available here and at MEDISCIENCETECH.com and is available on request. It applies to all Executive, Officers and Directors. There have been no waivers to any of the Code provisions nor any amendments made to the Code during 2006 or up to February 28, 2007 and/or the date of this 10-KSB 2006 SEC EDGAR filing. These systems, including but not limited to a review of registrants approach to internal financial control, its processes, outcomes and disclosures; review of the reports from the auditors past and present on their professional and regulatory compliance in order to maintain independence and objectivity, including the possible rotation of partners; all which accord with within the provisions OF Sarbanes-Oxley Act"code" applicable to registrant as a Non-Accelerated SEC filer have been in place for Fiscal year ending Feb 28, 2007 and 2006 involving the identification, evaluation and management of key risks through business reviews by the Board; and the review by the Audit Committee of internal financial controls and the management process. These systems are to be reviewed annually by the Board. It is important to advise that such systems are not providing absolute assurance against material misstatements or loss; these systems are designed to identify and manage those risks that could adversely impact the achievement of the MTC objectives. The Chairman/CEO and Chief Financial Officer Frank Benick have evaluated the effectiveness of the design and operation of registrants disclosure controls and procedures as at February 28, 2007. Based upon, and as of the date of, that evaluation, they concluded that the disclosure controls and procedures were effective, in all material respects, to ensure that information required to be disclosed in the SEC reports that MTC files and submits is recorded, processed, summarized and reported as and when required. Management will continue to refine the governance issues for compliance effectiveness in year 2007. Corporate Governance and Management's Responsibility We, Peter Katevatis Chairman/CEO, John Kennedy Chairman Audit Committee, and Frank Benick CPA Chief Financial Officer, the Sarbanes compliant management of Mediscience Technology Corp., are responsible for the integrity and objectivity of the accompanying financial statements and related information. We are also responsible for ensuring that financial data is reported accurately and in a manner that facilitates the understanding of this data. We maintain a well-designed periodically reviewed system of internal accounting controls, encourage open, strong and effective corporate governance from our employees, consultants, executives. The Directors, continuously review business results and strategic choices and focus on financial stewardship. Our accountants and CFO monitor and critique our system of internal accounting controls designed to provide reasonable assurance material assets are safeguarded and that transactions and events are recorded properly. Our internal controls include self-assessments and reviews. During 2004 the Company invested significant time and cash resources (audit and legal review) addressing our internal control system, and our compliance obligations as a non-accelerated SEC filer (see SEC filed SB-2 130 pg. registration document effective Jan 12, 2005) in order to ensure compliance with Section 404 of the Sarbanes-Oxley Act of 2002. We have concluded that our internal control over financial reporting was effective as of January 12, 2005 and continues so effective as of February 28, 2006 and February 28, 2007 We have a systematic certification program and a yearly sworn D&O questionnaire required of all directors to ensure compliance with these policies at all employee levels. Our Audit Committee of the Board of Directors is composed of (2) independent directors with the financial knowledge and experience to provide appropriate oversight. We review internal control matters and key accounting and financial reporting issues with the Audit - 24 - Committee on a regular basis including a quarterly 10-Q review and discussion meeting. In addition, the independent auditors, CFO and retained counsel may meet in private sessions with our Audit Committee to discuss the results of their work including observations on the adequacy of internal financial controls, the quality of financial reporting and confirmation that they are properly discharging their responsibilities and other relevant matters. Our Intent is to ensure that we maintain objectivity in our business assessments, constructively challenge the approach to business opportunities and issues and monitor our business results and the related controls. Our consolidated financial statements and financial data that follow have been prepared in conformity with accounting principles generally accepted in the United States of America and include amounts that are based upon our best judgments. We are committed to present and discuss results of operations in a clear and transparent manner in order to provide timely, accurate and understandable information to our shareholders, In compliance with Section 404 of the Sarbanes-Oxley Act of 2002. /s/ Peter Katevatis Esq., Chairman/ Chief Executive Officer /s/ Frank Benick, Chief Financial Officer /s/ John Kennedy, Chairman Audit committee Item 8B. Other Information Based In concert with equity partner Info tonics Technology Center and after review of the Company' s accumulated patent portfolio including both licensed and MTC proprietary IP it is the registrants position to concentrate its IP investment and product development effort in the CD-R and CPE in its most market viable applications as determined by the parties. The initial collaborative research and development agreement of Nov 9, 2004 between registrant and Info tonics has been successfully completed as of May 31, 2007 The parties have executed a new agreement dated May 31, 2007 filed as exhibit to an 8-K filing dated which continues their collaborative relationship. The parties will focus any and all secured investment into near-term market entry based upon MTC proprietary IP. All unrelated licensed IP (imaging in turbid media) will not be pursued as a Mediscience-Infotonic development effort. This continued partnership between BioScopix, Mediscience, and Infotonics presents an important opportunity for the advancement of medical equipment and diagnostic methods that utilize optical fluorescence and optical biopsy in the application and interpretation of induced auto fluorescence as a means of assessing biological processes. In furtherance of the parties continual pursut of grant support Medical consultant Dr. Fredrick Naftolin advised that registrant New York subsidiary BioScopix Inc. on May 24, 2007 was awarded $23,066 by the Finger Lakes New Knowledge Fusion Project Seed Grant Funding Program, forregistrants proposal entitled: "Use of Vulvar Autofluorescence in Dairy Cows to Improve Breeding." PART III Item 9. Directors, Executive Officers, Promoters , Control Persons and Corporate Governance; Compliance with Section 16 (a) of the Exchange Act The following table sets forth the name, age, position and term of directorship, as applicable, of each of our directors and executive officers. Directors are elected annually. Officers are selected by the Board of Directors and serve at the pleasure of the Board.
Name Age Position(s) - --------------------------- --------- -------------------------------------------------- Frank D. Benick, CPA, CVA 58 Chief Financial Officer - 25 - Peter Katevatis Esq. 73 Chairman of the Board, Treasurer, Chief Executive Officer John M. Kennedy 69 Director, Vice President, Secretary William Armstrong 89 Director Michael N. Kouvatas, Esq. 78 Director
Each director holds office until the next annual meeting of shareholders or until their successors have been duly elected and qualified. Executive officers are appointed and serve at the discretion of the Board of Directors. No compensation has been paid to any individual for services rendered as a director. Management Biographies Peter Katevatis has served as Chairman of the Board of Directors and Chief Executive Officer since 1993 and as a director since 1981. As of April 24, 2006 he has served as interim President. On March 5, 2007 the board extended his employment agreement as CEO until 2015. (see 8-K dtd March 10, 2007) Mr. Katevatis was elected Treasurer of the Company in January 1996. Mr. Katevatis has been a practicing attorney in Philadelphia, Penn. and Marlton, New Jersey, and is licensed as an attorney in New York and in the District of Columbia. Mr. Katevatis served as trustee of the New Jersey State's Police and Fireman Retirement Pension Fund from 1989 to 1996 and as a member of the New Jersey Investment Council from 1990 to December 1992. He is a member of the American Arbitration Association, serves a listed arbitrator with the National Association of Security Dealers, a member of the National District Attorney's Association and the New York Academy of Science. John M. Kennedy currently serves as a Vice President, and Secretary of our company, and has been a director of the Company since 1982 and chairman of the audit committee since 2000. Mr. Kennedy served as Vice President since 1983, as Treasurer from 1984 to January 1996 and as Secretary since 1986. Mr. Kennedy is Chief Executive Officer of Pepco Manufacturing Co., a sheet metal fabricator for the electronics industry. Mr. Kennedy also was a director and member of the Audit Committee of First Peoples Bank of New Jersey from 1979 and also served as a member of its executive board until 1994 when Core-States Bank purchased First Peoples Bank. William W. Armstrong has served as a director since 1978 and as a member of the audit committee since 2000. Mr. Armstrong has been in retirement since 1982 following a 36 year career as a research scientist with Pfizer Inc, a global consumer health care and pharmaceutical company. Since his retirement, Mr. Armstrong has continued to serve as a consultant to Pfizer, currently in the animal health division. Mr. Armstrong has been awarded 14 patents concerning therapeutic agent dosage delivery systems. Michael N. Kouvatas has served as a director since 1971 and as an independent member of the audit committee as of April 6, 2005. For the past 10 years, Mr. Kouvatas has been an attorney with offices in Haddonfield, New Jersey and is a principal in various business operations in the Southern New Jersey area. There are no family relationships between any of our directors or executive officers. Board Committees The Board of Directors has six structured standing committees: Audit Committee, Committee on Corporate Governance, Compensation and Benefits Committee, Executive Committee, Finance Committee, and Committee on Public Policy and Social Responsibility. Members of the individual committees are named below: Registrant has retained a Chief Financial Officer with appropriate Sarbanes-Oxley credentialed experience. - 26 -
Committee on Committee on Public Policy and Corporate Compensation and Social Audit Governance Benefits Executive Finance Responsibility - ----------------- ----------------- ---------------- ----------------- ----------------- ----------------- John Kennedy* Michael Kouvatas John Kennedy* John Kennedy* John Kennedy* All directors Michael Kouvatas John Kennedy* Michael Kouvatas Michael Kouvatas* William Armstrong William Armstrong Peter Katevatis Peter Katevatis* Peter Katevatis Michael Kouvatas William Armstrong (*) Chairperson
The Board has determined that John Kennedy is the audit committee financial expert. The Board, which is comprised of two independent directors, made a qualitative assessment of John Kennedy's and the other two member's level of knowledge and experience based on a number of factors, including their education and experience. The Audit Committee, its Charter is also available on the Company's website. MEDISCIENCETECH.com The Committee on Corporate Governance is comprised of four directors three of which are independent. The Committee assesses the size, structure and composition of the Board and Board Committees and acts as a screening and nominating committee for candidates considered for election to the Board. The Committee, Its Charter is available on the Company's website. MEDISCIENCETECH.com The Compensation and Benefits Committee, which is comprised of two independent directors, consults generally with management on matters concerning executive compensation and on pension, savings and welfare benefit plans. It makes recommendations on compensation generally, executive officer salaries, bonus awards and stock option grants, special awards and supplemental compensation. Its Charter is available on the Company's website. MEDISCIENCETECH.com The Executive Committee (3) which is comprised of two independent directors, Michael Kouvatas Esq. and John Kennedy-- -Peter Katevatis Esq. CEO, chair of the Audit committee, act for the Board of Directors when formal Board action is required between meetings in connection with matters already approved in principle by the full Board or to fulfill the formal duties of the Board. The Finance Committee, which is comprised of two independent directors, considers and makes recommendations on matters related to the financial affairs and policies of the Company, including capital structure issues, dividend policy, investment and debt policies, asset and portfolio management and financial transactions, all as necessary. Its Charter is available on the Company's website. MEDISCIENCETECH.com The Committee on Public Policy and Social Responsibility, which is comprised of all directors, advises the Board and management on Company policies and practices that pertain to the Company's responsibilities and its obligations as a Bio-Medical company whose products and services, might affect health and quality of life around the world. Its Charter is available on the Company's website. MEDISCIENCETECH.com Board and Board Committee Meetings Since March 1, 2006 the Board of Directors met 4 times, August 29, 2006, December 19, 2006, January 30, 2007 and March 5, 2007, with all above committee members present. All incumbent directors attended 90 percent of the meetings of the Board and of the committees on which they served. Compensation Committee Interlocks and Insider Participation: NONE - 27 - Item 10. Executive Compensation The following sets forth information for the three most recently completed fiscal years concerning the compensation of (i) the Chief Executive Officer and (ii) all other executive officers who earned in excess of $100,000 in salary and bonus in the fiscal year ended February 28, 2007.
SUMMARY COMPENSATION TABLE Nonqualified Non-Equity Deferred Stock Option Incentive Plan Compensation All Other Awards Awards Compensation Earnings Compensation Total Name and Principal Position Year Salary ($) Bonus ($) ($) ($) ($) ($) ($) ($) Peter Katevatis 2007 $200,000 -- -- -- -- -- $60,961 (1) $260,961 Chairman, Interim Pres. 2006 $200,000 -- -- -- -- -- $67,671 (1) $267,671 and Chief Executive 2005 $200,000 -- -- -- -- -- $70,055 (1) $270,055 Officer (PEO) Michael Engelhart 2007 $ 60,000 -- -- -- -- -- $ 1,315 (2) $ 61,315 President and Chief 2006 $120,000 -- -- -- -- -- $ 9,134 (2) $129,134 Operating Officer (PEO)* 2005 $120,000 -- -- -- -- -- $ 4,030 (2) $124,030
(1) Includes annual retainer of $50,000 for the provision of legal services, automobile expense of $ 5,882 and health insurance of $5,079 for 2007, an annual retainer of $50,000 for the provision of legal services, automobile expense of $ 5,292 and health insurance of $12,379 for 2006 and an annual retainer of $50,000 for the provision of legal services, automobile expense of $ 8,612 and health insurance of $12,043 for 2005. (2) Includes health insurance of $1,315 for 2007, automobile expense of $1,730 and health insurance of $7,404 for 2006 and automobile expense of $710 and health insurance of $ 3,320 for 2005. * Mr. Engelhart's employment contract as President & COO terminated by its terms April 23, 2006. Employment Agreements Peter Katevatis, our Chairman of the Board and Chief Executive Officer, has an employment agreement with us ending March 5, 2015. The Agreement provides that Mr. Katevatis will be compensated at an annual base salary of $250,000 (with an annual cost of living increase of no less than 6%) with a discretionary annual bonus in an amount to be determined in accordance with a formula to be agreed upon by the Board of Directors and Mr. Katevatis. The agreement may be terminated by us for cause upon ninety days notice and by Mr. Katevatis for any reason, and by us without cause, upon sixty days notice. If Mr. Katevatis is terminated by us without cause, he will be entitled to his base salary for the balance of the term of the Agreement and 200% of his annual bonus paid for the most recently ended fiscal year. Michael Engelhart, our President and Chief Operating Officer, employment agreement with registrant terminated in total by its terms April 23, 2006. Change of Control Our 1999 Stock Incentive Plan and our 2003 Consultants Stock Option, Stock Warrant and Stock Award Plan provide that all outstanding options, warrants and restricted stock will become vested and immediately exercisable, in the case of options and warrants, or free from all restrictions, in the case of restricted stock, upon the change of control of our company. OUTSTANDING EQUITY AWARDS AT FISCAL YEAR-END TABLE - 28 -
Option Awards Stock Awards Equity Incentive Equity Equity Incentive Plan Awards: Incentive Plan Awards: Market or Number of Number of Plan Awards: Market Number of Payout Value Securities Securities Number of Number of Value of Unearned of Unearned Underlying Underlying Securities Shares or Shares or Shares, Units Shares, Units Unexercised Unexercised Underlying Units of Units of or Other or Other Options Options Unexercised Option Stock That Stock That Rights That Rights That (#) (#) Unearned Exercise Option Have Not Have Not Have Not Have Not Options Price Expiration Vested Vested Vested Vested Name Exercisable Unexercisable (#) ($) Date (#) ($) (#) ($) Peter Katevatis Michael Engelhart
DIRECTOR COMPENSATION TABLE Change in Pension Value and Nonqualified Non-Equity Deferred Fees Earned or Incentive Plan Compensation All Other Paid in Cash Stock Awards Option Awards Compensation Earnings Compensation Total Name ($) ($) ($) ($) ($) ($) ($) - --------------------- -------------- ------------ ------------- -------------- ------------- ------------ ----- Peter Katevatis Esq. -- -- -- -- -- -- -- John M. Kennedy -- -- -- -- -- -- -- William Armstrong -- -- -- -- -- -- -- Michael N. Kouvatas -- -- -- -- -- -- --
Scientific/Medical Advisory Board The Company established a Scientific Advisory Board in January, 1993 under the chairmanship of Co-Founder Professor Robert R. Alfano to provide critical review and analysis of its research and product development programs in the area of photonics (lasers and optics) and to serve as a source of information on new product ideas, new technologies and current research activities. Its function served the Company well during the formative stages of its research. With the completed research at CUNY and the now present emphasis on commercialization of our IP, the Board consisting of Dr. Alfano and one other continuing member, is being expanded to include increased representation from the medical arts, including pathology, OBGYN and will be staffed with medical specialists who are skilled in the medical fields of primary interest to the Company. We believe that we have attracted accomplished clinicians who will help guide us in clinical study design aimed at gaining regulatory approval for commercial applications of our diagnostic technology. They will also be called upon to advise us about priorities and unmet needs in their respective disciplines and in matters such as physician's habits and preferences that would bear on product design and configuration. Dr. Fredrick Naftolin Contracted Senior Medical Consultant Date of Birth: April 7, 1936 1955 A.A., University of California, Los Angeles - 29 - 1958 B.A., University of California, Berkeley (Honors) 1961 M.D., University of California, School of Medicine San Francisco (Honors) 1970 D.Phil., University of Oxford, Oxford, England 1961-62 Intern, King County Hospital, Seattle, Washington 1962-66 Resident, Obstetrics and Gynecology, UCLA Medical Center, Los Angeles (D.G. Morton) 1966-67 Research Training Fellow, University of Washington, Seattle (S. Klebanoff) 1967-68 Senior Endocrine Fellow, Department of Medicine, University of Washington, Seattle (C.A. Paulsen) 1968-70 Graduate studies, University of Oxford, Department of Human Anatomy, Oxford, England (G.W. Harris) Professional Experince: 1986 Director, Center for Research in Reproductive Biology, Yale University 1984 Professor of Biology, Department of Biology, Yale University (Joint appointment) 1982-83 Professor Invite, Department of Morphology, University of Geneva, Faculty of Medicine 1978 Professor and Chairman, Department of Obstetrics and Gynecology, Yale University School of Medicine 1975-78 Professor and Chairman, Department of Obstetrics and Gynecology, McGill University, Faculty of Medicine, Montreal 1975-78 Obstetrician and Gynecologist-in-Chief, Royal Victoria Hospital, Montreal 1973-75 Associate Professor of Obstetrics and Gynecology, Harvard Medical School 1972-73 Associate Professor of Obstetrics and Gynecology, University of California, San Diego 1970-72 Assistant Professor of Obstetrics and Gynecology, University of California, San Diego 1966-68 Research Associate and Assistant Chief, Gynecology Service, USPHS Hospital, Seattle, Washington Selected Honors: 1958 Sigma Xi 1961 Alpha Omega Alpha 1968 J.P. Lane Award, United States Public Health Service Clinical Society 1968-70 NIH Special Research Fellowship (NICHHD) 1971 Squibb Prize paper, American Fertility Society 1975 Fellowship, American College of Obstetricians and Gynecologists 1975 M.A. (Hon.), McGill University, Montreal, Canada 1978 M.A. (Hon.), Yale University, New Haven, Conn. 1980 Fellow, Silliman College, Yale University 1982-83 Fogarty Senior International Fellow 1983 John Simon Guggenheim Jr. Memorial Fellow 1985 Wyeth Lecturer, Canadian Fertility and Andrology Society 1985 Royal College of Physicians and Surgeons of Canada Lecturer, University of Saskatchewan, Canada 1986 Royal College of Physicians and Surgeons of Canada Lecturer, University of Western Ontario, Canada - 30 - 1986 Fellowship, The American Gynecological and Obstetrical Society 1988 Lecturer, Frontiers of Reproductive Biology, Society for Study of Reproduction 1988 Plenary Lecturer, First Congress of the International Society of Gynaecological Endocrinology 1989 Keynote Speaker, 17th Annual New England Endocrine Conference 1991-92 President, Society for Gynecologic Investigation 1992-93 Berlex International Scholar 1997 Latta Distinguished Lecturer, University of Nebraska Medical School 1997-98 President Elect, North American Menopause Society Scientific Committee Chairman, North American Menopause Society Fellow ad eundem of the Royal College of Obstetricians and Gynaecologists "Frederick Naftolin Fellowship in Reproductive Biology" to be awarded annually by McGill University Faculty of Medicine 1999 Visiting Professor, "Extraordinary Professor, Chair in Advances in Medicine in Reproduction", Complutense University, Madrid, Spain Licensure:California Connecticut Specialty Board: Obstetrics and Gynecology (1972) Societies: Alpha Omega Alpha, Sigma Xi, The Endocrine Society, The Pacific Coast Fertility Society (Honarary Member), Canadian Andrology and Fertility Societies (Honorary Member), Society for Gynecologic Investigation, International Society of Neuroendocrinology, International Society of Psychoneuroendocrinology, American Gynecological and Obstetrical Society, International Society for Gynecological Endocrinology .,Society for Neuroscience, North American Menopause Society,International Menopause Society, Israeli Fertility Society Editorial Boards: 1998 Proceedings of the Society for Experimental Biology and Medicine 1997 Climacteric, Journal of the International Menopause Society 1996 Founding Editorial Advisory Board, African Journal of Reproductive Health 1995 Founding Editorial Board, Early Pregnancy: Biology and Medicine 1993 Founding Editorial Board, Menopause 1993 Founding Associate Editor, Journal of the Society for Gynecologic Investigation 1988-95 Biomedicine and Pharmacotherapy 1988-93 Resident and Staff Physician 1987 Gynecological Investigation 1987-91 Endocrine Reviews 1987 Video Journal of Obstetrics and Gynecology 1980-88 Drug Intelligence and Clinical Pharmacy (editorial panel) 1979-82 New England Journal of Medicine 1979-82 Journal of Steroid Biochemistry 1974-92 Psychoneuroendocrinology The Chairman is Dr. Robert R. Alfano* distinguished Professor of Science and Engineering and the Director of the IUSL at the City College of CUNY. He is co-author of a number of patents concerning the Company's photonic technology. and a *principal stockholder and co-founder of the Company. He has supervised the research and development of registrants cancer diagnostic technology as principal investigator at CCNY. . In May 1989, Dr. Alfano was elected a Fellow of the Optical Society of America for his studies of ultra fast phenomena. He received his B.S. and M.S. degrees in Physics from Farleigh Dickinson University in 1963 and 1964, respectively. He received his Ph.D in Physics from New York University in 1972. Dr. Alfano holds over 73 - 31 - patents and has published over 600 papers. Dr. Alfano's contract as company paid consultant expired by its terms March 5, 2007 (See infra) Stimson P. Schantz, M.D. is Director of Cancer Prevention, Department of Surgery Cornell University Memorial Sloan-Kettering Cancer Center, New York. Dr. Schantz has been appointed as the principal investigator under the Company's Clinical Trial Agreement with Memorial Hospital for Cancer and Allied Diseases and in such capacity, oversees the pilot study of tissue auto fluorescence pursuant to such agreement. Between 1984 and 1991, Dr. Schantz served in various faculty positions at the M.D. Anderson Cancer Center in the Department of Head and Neck Surgery. Dr. Schantz is presently a member of the Society of Surgical Oncology, American Society for Head and Neck Surgeons, the Society of Head and Neck Surgery, and has served as the Director of research programs and as a member of the research committee at the University of Texas, M.D Anderson Cancer Center. He has been the recipient of several honors and awards, including the First Independent Investigator Award of the National Cancer Institute awarded in March 1988 and an NCI contract to study biomarkers awarded in 1995. Dr. Schantz serves as reviewer and editor of a number of professional medical publications and is the author of numerous articles, papers, books and chapters, and abstracts. He was awarded a Bachelor of Arts Degree from Harvard College in 1970 and his M.D. from the University of Cincinnati in 1975. In April, 1998 Dr. Schantz was recruited to lead a multi-institutional effort revolving around cancer prevention clinical research programs and constituting a consortium effort with hospitals in the metropolitan New York City area supported by the National Cancer Institute approval and high priority rating on a $1.6 million dollar grant to carry out collaborative clinical trials which will be targeted specifically at developing Mediscience Technology and positioned to conduct phase II and phase III trials on a multi-organ basis involving diseases of the breast, upper and lower aerodigestive tract, and gynecologic tissues. Stephane Lubicz, M.D. EDUCATION: 1965-1968 BS, Cum Laude, Free University of Brussels, Belgium. M.D., - Free University of Brussels, Belgium. PROFESSIONAL EXPERIENCE: Pharmaceutical, Medical and Gynecologic Oncology I. Pharmaceutical Industry Experience (A) USA consultant to B. & A, Inc. The Company operates for the coordination and organization of clinical trials in Mexico (and throughout Latin America). This includes all Phase II, III trials and post marketing surveillance activities through Phase IV Clinical trials). (B) Medical director, Clinical Development Oncology Daiichi Pharmaceutical Corporation, Montvale, NJ (08/2000-011/2002) (I) Phase III: Project Pancreas- Global (US and Europe: Protocol Global project (Japan, USA + Mexico, EU) (II) Phase II: completion and initiation of multiple Phase II studies: Solid tumors and leukemia's, initiations and monitoring of sites and investigators for Phase II (US, Canada, Mexico) (2) TZT-1027 project: Global project with Japan and EU (parallel and or complementary studies in EU and Japan) Phase II: All Solid Tumors. Phase II includes 3 studies (use of a template protocol for multiple protocols/drug projects). (3) CPT-11 project: Gynecologic Project. Finalization of project in gynecologic malignancies and selection of endometrial cancer project (a Phase II study Clinical experience: 1969-1971 Rotating Externship, Brussels University Hospitals, Brussels, Belgium. 1971-1972 Rotating Internship, Brussels University Hospitals, Brussels, Belgium. 1972-1975 Residency, Obstetrics and Gynecology, Brussels University Hospital and Affiliated Hospitals, Belgium. 1975-1979. Residency, Obstetrics and Gynecology. The Jewish Hospital and Medical Center of Brooklyn, N.Y.1979-1981 Fellow, Gynecology Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences. Mount Sinai School of Medicine, New York, N.Y. 1981-1982 Attending Physician, Department of Obstetrics and Gynecology, Mount Sinai Hospital Medical Center of Chicago, Chicago, IL. 1981-1982. Assistant Professor, Rush Medical College, Chicago, IL.1981-1982. Director of Medical Education for Residents and Students, Rush Medical College, Chicago, IL.1982-1984 Full-time Attending, Department of Obstetrics, Gynecology, and Reproductive Science, The Mount Sinai Medical Center, New York, N.Y.1982-1984 Assistant Director, Division of Gynecologic- Oncology, Department of Obstetrics & Gynecology, and Reproductive Science, The Mount Sinai Medical Center, New York, N.Y.1982-1991 Instructor, Mount Sinai School of Medicine, New York, N.Y. 1982-1984 Assistant Attending, Department of - 32 - Obstetrics and Gynecology, The City Hospital Center at Elmhurst, N.Y. 1982-1984 Assistant Director, Gynecologic Oncology, Dept of Obstetrics and Gynecology, The City Hospital Center at Elmhurst, N.Y 1985 to 1994-Pres Attending, The Mount Sinai Medical Center, New York, N.Y., LaGuardia Hospital, Queens, N.Y., Doctors Hospital, New York, N.Y. St. Vincent Hospital, New York, Syosset Community Hospital, L.I. St. Clare's Hospital, N.Y.C. 1995-1996 Director, Division of Gyn/Oncology St.Vincent's Hospital, N.Y 07/00-11/02Director of Oncology, Clinical development, Daiichi Pharma. Corp Montvale, New Jersey (Japan, Canada, Mexico and Europe) CERTIFICATION: E.C.F.M.G., July 25, 1973, #202-214-3. Board Certified in Obstetrics and Gynecology, July 1977, Belgium., Board Certified in Obstetrics and Gynecology, November 1982, U.S.A., Board Certified in Gynecologic Oncology, December 1987., HIP Panel, Sub-Specialty Gynecologic Oncology, January 1988- June 1996. The Scientific Advisory Board is paid a fee of $1,000 for each meeting attended. Ronald Tygar President and Chairman of RT Industries, a NASDAQ publicly held manufacturing and distribution Company specializing in Automobile brakes and automotive computer parts; Chairman of RT funding Corp., a New York State based mortgage lender; President and chairman of RT consultants advisory services in business development, corporate marketing, manufacturing and distribution operations. Mr. Tygar will counsel the Mediscience management team on matters pertaining to business development, corporate marketing, and manufacturing and distribution operations. Jeremy Rosen DDS Presents extensive Medical/Dental/Oral Health experience regarding FDA Clinical, structuring, management, and overview and expertise in the area of Dental/Oral applications of the Company's Technology. Dr. Rosen will be supporting/participating in management presentations seeking corporate funding and/or corporate relationships. Dr Rosen together with director William Armstrong have agreed to review registrants interest in oral cancer diagnostics. - 33 - Item 11. Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters The following table sets forth, as of May 31, 2007, certain information concerning the beneficial ownership of common stock by (i) each person known by the company to be the owner of more than 5% of the outstanding common stock, (ii) each director, (iii) each Named Executive Officer, and (iv) all directors and executive officers as a group. In general, "beneficial ownership" includes those shares a director or executive officer has the power to vote or the power to transfer, and stock options and other rights to acquire common stock that are exercisable currently or become exercisable within 60 days. Except as indicated otherwise, the persons named in the table below have sole voting and investment power with respect to all shares shown as beneficially owned by them. The calculation of the percentage owned is based on 65,459,274 shares outstanding (plus, with respect only to each holder of securities that are exercisable for or convertible into common stock within 60 days, shares underlying such securities). Percentage of Amount and Nature Outstanding Name and Address of Beneficial Ownership Shares Owned - -------------------------------------- ----------------------- -------------- William W. Armstrong P.O. Box 607 Tupper Lake, NY 12986................. 350,000 (1) * Michael Engelhart*2 161 North Franklin Turnpike Ramsey, NJ 07446...................... -- (2) * Peter Katevatis 1235 Folkestone Way Cherry Hill, NJ 08034................. 9,816,343 (3) 14.98% John M. Kennedy 802 Chestnut Avenue Somerdale, NJ 08083................... 2,535,933 (6) 3.87% Michael N. Kouvatas 27 Kings Highway East Haddonfield, NJ 08033............ 424,666 (4) * John Matheu *2a 215 Longhill Drive Short Hills, NJ 07078................. -- (5) * All directors and executive officers as a group (7 persons)....... 13,161,942 20.10% - ------------ *Represents less than 1% (1) Includes 6,000 shares held by Mr. Armstrong's wife for which Mr. Armstrong disclaims beneficial ownership. (2) April 23, 2006 Michael Engelharts three year employment agreement April 23, 2003 to April 23, 2006 ended (his employment contract is part of and an attachment to Registrants SEC 10-K 2003 page 44 herein incorporated by reference. CEO, Chairman Katevatis assumed the interim role of President April 24, 2006. (2a) Employment agreement terminated by its terms on April 23, 2006 no shares were issued or vested as of February 28, 2006. - 34 - (3) Includes 6,217,357 (5,349,794 shares and 867,563 shares issued January 20, 2005 as correction, 50,499,149 shares subject to 17% anti-dilution right all issued pursuant to an anti-dilution agreement/resolution nunc pro tunc dated July 16, 2004 between the Board and Mr. Katevatis, and (ii) 1,416,667 shares issued at $0.25 in lieu of salary and fees for legal services rendered to us by Mr. Katevatis, (iii) 552,664 shares issued in connection with a salary reduction required by the terms of a private placement of our stock, and (iv) 398,167 shares received in a cashless exercise of a stock option. (total 2,367,498) (See Katevatis employment agreement for terms 10-K 2005 incorporated herein by reference thereto) (see SEC Form 5 filed March 2006 incorporated and made a part hereof) Excludes 200,000 shares owned by Mr. Katevatis daughter as custodian for his grandchildren, and a total of 500,000 shares owned by his sons, as to all of which he disclaims beneficial ownership. (4) Includes (i) 118,000 shares owned by Mr. Kouvatas's wife for which Mr. Kouvatas, disclaims beneficial ownership; and 40,000 shares currently in the estate of Mr. Kouvatas' son of which Mr. Kouvatas and his wife are beneficiaries. Includes restricted shares acquired by Mr. Kouvatas pursuant to the exercise of stock options, 6000 shares for which Mr. Kouvatas is custodian for three (3) of his children and 36,000 shares for which Mr. Kouvatas's daughter is custodian for her two children under the New Jersey Uniform Gift to Minors Act; and 30,000 shares registered in the names of each his children. (5) Includes 300,000 shares subject to a stock option at $1.50 per share. (6) Includes the issuance of a net of 1,833,333 restricted shares acquired by Mr. Kennedy pursuant to the exercise of stock options On December 13, 1985. The Company granted stock options at an exercise price of $0.25 per share to the following Officers and Directors in exchange for cancellation of certain of the Company's accrued indebtedness to such persons, portions of which were assigned as follows: Mr. Katevatis received options to purchase 4,400,000 shares (2,200,000 of which were assigned by Mr. Katevatis to Mr. Kennedy); and also includes 100,000 shares registered in the name of Mr. Kennedys wife. NOTES NOTE 1 Board minute/action of July16, 2004 in support of historical contractual continual anti-dilution (JV) issuances to Peter Katevatis and Robert Alfano founders is incorporated in its entirety and made a part hereof. (see SB-2 SEC registration filing exhibits board minute resolution SB-2 shares held by Katevatis and Alfano. "RESOLVED, that the Corporation's agreement to issue, from time to time, additional shares of Common Stock to Katevatis such that the Katevatis Shares represent the Katevatis Anti-Dilution Percentage (17%) and the Alfano Shares represent the Alfano Anti-Dilution Percentage (4%) of the issued and outstanding shares of Common Stock, and is hereby unanimously ratified, confirmed and approved nunc pro tunc in all respects". All Katevatis Anti-dilution transactions reflected in FORM 4 and Form 5 Filings Katevatis SEC Form 4 filing dated 09/13/2004 Total shares issued as per his JV ant-dilution requirement 7, 717,292 (all SEC rule 144; legend) Katevatis SEC Form 4 filing dated 05/ 13/2005 Total shares issued to March 30, 2005 per his JV ant-dilution requirement 9,220,895 (all SEC rule 144 legend) Katevatis SEC Form 5 filing dated Feb 28,2006 Total shares issued to Feb 28,2006 per his JV ant-dilution requirement 9,332,558 (all SEC rule 144 legend) Item 12. Certain Relationships and Related Transactions, and Director Independence Mr. Katevatis is paid $50,000 for legal services rendered to us during each fiscal year. Mr. Katevatis received $50,000 for each of our fiscal years commencing in 1998 through 2007. In July 2002, we entered into a month-to-month lease agreement with Peter Katevatis, our Chairman and Chief Executive Officer, for approximately 3,000 square feet for our corporate offices for which we pay no rent but have assumed the obligation to pay all taxes, maintenance, insurance, utilities and repairs relating to such premises. This agreement is still in effect. Mr. Katevatis and Dr Robert Alfano have agreed to forebear any and all collection action for accrued salary and fees including forgiveness of interest in exchange for the option of converting any such accrued salary and fees into our common stock at $0.25 per share. If we receive financing, either may elect to receive all or part of such accrued salary or fees in cash or common stock. As of February 28, 2007, accrued salary and fees amounted to $1,689,667 for Mr. Katevatis. As of February 28, 2007, accrued consulting fees amounted to $1,394,818 for Dr Alfano. On December 1, 1988, we acquired from Dr. Robert Alfano, a principal shareholder, all of the issued and outstanding stock of LDI including the "Method and Apparatus for Detecting Cancerous Tissue Using Visible Luminescence" patent in exchange for 1,500,000 shares of our Common Stock. LDI is under a continuing obligation to pay a royalty in the aggregate amount of 1% of gross sales from any equipment made, leased or sold which embodies the concepts described in such patent to Michelle Alfano, Dr. Alfano's daughter. The "516" patent expired by its terms on________________. As of February 28, 2006, accrued consulting fees amounted to $1,394,818 for Dr Alfano As of February 28, 2006, accrued consulting fees amounted to $ 1, 232,818 for Dr Alfano. - 35 - On August 1, 2004, registrant entered into a consulting agreement with John Matheu, a director, former member of the audit committee to April 6, 2005. Mr. Matheu provided management consulting services and was paid a monthly consulting fee of $4,166 and received an option to purchase 300,000 shares of Common Stock at $1.50 per share. The agreement terminated on April 6, 2006. * Matheu SEC form 5 filed dated April 19, 2006 reflects 25,000@$0.17 and 6,500 @ $ 0.20 shares disposed of as sales February 14, 2006. Mr. Matheu disclosed this transaction to the board on April 19, 2006. After an investigation was completed April 28,2006, he was removed for cause by majority board action on May 2, 2006. On July16, 2004 Board minute/action in support of contractual anti-dilution (JV) issuances to co-founders Peter Katevatis and Robert Alfano is incorporated in its entirety and made a part hereof. (see SB-2 SEC registration filing effective Jan. 12, 2005 with exhibits including board minute resolution. Reported shares by the company's transfer agent, Registrar and transfer Co., on February 28, 2005 held by Peter Katevatis 8,921,525 and Robert Alfano 1,946,588 "RESOLVED, that the Corporation's agreement to issue, from time to time, additional shares of Common Stock to Katevatis such that the Katevatis Shares represent the Katevatis Anti-Dilution Percentage (17%) and the Alfano Shares represent the Alfano Anti-Dilution Percentage (4%) of the issued and outstanding shares of Common Stock, and is hereby ratified, confirmed and approved nunc pro tunc in all respects" None of these transactions involved any underwriters, underwriting discounts or commissions, except as specified below, or any public offering, and we believe that each transaction was exempt from the registration requirements of the Securities Act by virtue of Section 4(2) thereof and/or Regulation D promulgated there-under. All recipients had adequate access, through their relationships with us, to information about us. Director Independence The Board of Directors has determined that to be considered independent, an outside director may not have a direct or indirect material relationship with the Company. A material relationship is one which impairs or inhibits--or has the potential to impair or inhibit--a director's exercise of critical and disinterested judgment on behalf of the Company and its stockholders. In determining whether a material relationship exists, the Board consults with the Company's counsel to ensure that the Board's determinations are consistent with all relevant securities and other laws, recent relevant cases and regulations regarding the definition of "independent director," "business judgment" including those set forth in listing standards of the New York Stock Exchange as in effect from time to time. Consistent with these considerations, the Board affirmatively has determined that as of February 28, 2007 all directors are independent EXCEPT PETER KATEVATIS AND WILLIAM ARMSTRONG. (SEE BELOW) Item 13. Exhibits 31.1 Certification of the Chief Executive Officer required by Rule 13a-14(a) or Rule 15d-14(a) 31.2 Certification of the Chief Financial Officer required by Rule 13a-14(a) or Rule 15d-14(a) 32 Certification of the Chief Executive Officer and the Chief Financial Officer required by Rule 13a-14(b) or Rule 15d-14(b) and 18 U.S.C. 1350 - 36 - Item 14. Principal Accountant Fees and Services Audit Fees The aggregate fees billed for each of the fiscal years ended February 28, 2007 and 2006 for professional services rendered by the principal accountant for the audit of our annual financial statements and reviews of the quarterly financial statements was $45,000 and $46,000, respectively. Audit Related Fees $21,000 Tax Fees $-0- All Other Fees $24,000 - 37 - MEDISCIENCE TECHNOLOGY CORP. INDEX TO CONSOLIDATED FINANCIAL STATEMENTS Page(s) Audited Consolidated Financial Statements: Report of Independent Registered Public Accounting Firm...........F-1 Consolidated Balance Sheet as of February 28, 2007................F-2 Consolidated Statements of Operations for the years ended February 28, 2007 and 2006...................................F-3 Consolidated Statements of Changes in Stockholders' Deficit for the years ended February 28, 2007 and 2006...............F-4 Consolidated Statements of Cash Flows for the years ended February 28, 2007 and 2006...................................F-5 Notes to Consolidated Financial Statements........................F-6 Report of Independent Registered Public Accounting Firm To the Board of Directors Mediscience Technology Corp. Cherry Hill, New Jersey We have audited the accompanying consolidated balance sheets of Mediscience Technology Corp. and subsidiaries (the "Company") as of February 28, 2007 and 2006, and the related consolidated statements of operations, changes in stockholders' deficit and cash flows for the years then ended. These consolidated financial statements are the responsibility of the Company's management. Our responsibility is to express an opinion on these consolidated financial statements based on our audits. We conducted our audits in accordance with the standards of the Public Company Accounting Oversight Board (United States). Those standards require that we plan and perform the audits to obtain reasonable assurance about whether the financial statements are free of material misstatement. An audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements. An audit also includes assessing the accounting principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation. We believe that our audits provide a reasonable basis for our opinion. In our opinion, the consolidated financial statements referred to above present fairly, in all material respects, the financial position of Mediscience Technology Corp. and subsidiaries as of February 28, 2007 and 2006, and the results of their operations and their cash flows for the years then ended, in conformity with accounting principles generally accepted in the United States. The accompanying consolidated financial statements have been prepared assuming that the Company will continue as a going concern. As disclosed in Note 1 to the financial statements, the Company has no revenues, incurred significant losses from operations, has negative working capital and an accumulated deficit which raises substantial doubt about its ability to continue as a going concern. Management's plan in regard to these matters is also described in Note 1. The financial statements do not include any adjustments relating to the recoverability and classification of asset carrying amounts or the amount and classification of liabilities that might result should the Company be unable to continue as a going concern. /s/ MORISON COGEN LLP Bala Cynwyd, Pennsylvania June 8, 2007 F-1 MEDISCIENCE TECHOLOGY CORP. AND SUBSIDIARIES CONSOLIDATED BALANCE SHEETS FEBRUARY 28, 2007 AND 2006
2007 2006 ------------ ------------ ASSETS CURRENT ASSETS Cash $ 138,508 $ 136,635 Prepaid expenses 25,536 4,031 ------------ ------------ TOTAL CURRENT ASSETS 164,044 140,666 EQUIPMENT - Net 1,162 2,107 DEFERRED CHARGES 750,994 1,114,682 OTHER ASSETS 1,800 1,800 ------------ ------------ TOTAL ASSETS $ 918,000 $ 1,259,255 ============ ============ LIABILITIES AND STOCKHOLDERS' DEFICIT CURRENT LIABILITIES Convertible debt, net of discount of $75,000 $ -- $ -- Accounts payable 35,971 29,204 Accrued liabilities 3,531,898 3,123,458 ------------ ------------ TOTAL CURRENT LIABILITIES 3,567,869 3,152,662 ------------ ------------ TOTAL LIABILITIES 3,567,869 3,152,662 ------------ ------------ STOCKHOLDERS' DEFICIT Convertible preferred stock - $.01 par value, 50,000 shares authorized, -0- shares issued and outstanding in 2007 and 2006, respectively -- -- Common Stock - $.01 par value; 199,950,000 shares authorized; 64,128,274 and 59,553,893 shares issued and outstanding in 2007 and 2006, respectively 641,283 595,540 ADDITIONAL PAID-IN CAPITAL 25,073,282 24,462,292 ACCUMULATED DEFICIT (28,364,434) (26,951,239) ------------ ------------ TOTAL STOCKHOLDERS' DEFICIT (2,649,869) (1,893,407) ------------ ------------ TOTAL LIABILITIES AND STOCKHOLDERS' DEFICIT $ 918,000 $ 1,259,255 ============ ============
The accompanying notes are an integral part of these consolidated financial statements. F-2 MEDISCIENCE TECHNOLOGY CORP. AND SUBSIDIARIES CONSOLIDATED STATEMENTS OF OPERATIONS YEARS ENDED FEBRUARY 28, 2007 AND 2006 2007 2006 ------------ ------------ SALES $ -- $ -- COST OF SALES -- -- ------------ ------------ GROSS PROFIT -- -- ------------ ------------ GENERAL AND ADMINISTRATIVE EXPENSE 1,156,102 1,890,356 RESEARCH AND DEVELOPMENT EXPENSE 260,137 320,953 ------------ ------------ TOTAL EXPENSE 1,416,239 2,211,309 ------------ ------------ LOSS FROM OPERATIONS (1,416,239) (2,211,309) OTHER INCOME Interest income, net of interest expense of $647 in 2007 and $190 in 2006 3,044 12,641 ------------ ------------ LOSS BEFORE INCOME TAX BENEFIT (1,413,195) (2,198,668) INCOME TAX BENEFIT -- -- ------------ ------------ NET LOSS $ (1,413,195) $ (2,198,668) ============ ============ BASIC AND DILUTED NET LOSS PER COMMON SHARE $ (0.023) $ (0.037) ============ ============ BASIC AND DILUTED WEIGHTED AVERAGE NUMBER OF SHARES OUTSTANDING 62,280,549 58,865,855 ============ ============ The accompanying notes are an integral part of these consolidated financial statements. F-3 MEDISCIENCE TECHNOLOGY CORP. AND SUBSIDIARIES CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' DEFICIT YEARS ENDED FEBRUARY 28, 2007 AND 2006
Preferred Stock Common Stock ----------------- ---------------------- Additional Common Number of Number Paid-in Stock Accumulated Shares Amount of Shares Amount Capital Subscribed Deficit ------- ------- ------------ -------- ----------- ---------- ------------ BALANCE AT FEBRUARY 28, 2005 -- $ -- 56,124,210 $561,243 $23,217,702 $ 250,000 $(24,752,571) Issuance of stock - previously subscribed -- -- 500,000 5,000 24,500 (250,000) -- Issuance of stock - future consulting services -- -- 1,366,000 13,660 618,380 -- -- Issuance of stock - anti-dilution rights -- -- 715,449 7,155 (7,155) -- -- Issuance of stock - cancellation of accrued expenses -- -- 74,834 748 16,419 -- -- Issuance of stock - services -- -- 23,400 234 4,446 -- -- Issuance of stock - cash -- -- 750,000 7,500 367,500 -- -- Net loss for the year ended February 28, 2006 -- -- -- -- -- -- (2,198,668) ------- ------- ------------ -------- ----------- --------- ------------ BALANCE AT FEBRUARY 28, 2006 -- -- 59,553,893 595,540 24,462,292 -- (26,951,239) Issuance of stock - prepaid lease -- -- 150,000 1,500 19,500 -- Issuance of stock - future consulting services -- -- 1,072,000 10,720 156,800 -- -- Issuance of stock - anti-dilution rights -- -- 760,050 7,599 (7,599) -- -- Issuance of stock - cancellation of accrued expenses -- -- 166,666 1,667 26,666 -- -- Issuance of stock - consulting services -- -- 93,000 930 13,950 -- -- Issuance of stock - cash -- -- 2,332,665 23,327 326,673 -- -- Discount on debt due to beneficial conversion option -- -- -- -- 75,000 -- -- Net loss for the year ended February 28, 2007 -- -- -- -- -- -- (1,413,195) ------- ------- ------------ -------- ----------- --------- ------------ BALANCE AT FEBRUARY 28, 2007 -- $ -- 64,128,274 $641,283 $25,073,282 $ -- $(28,364,434) ======= ======= ============ ======== =========== ========= ============
The accompanying notes are an integral part of these consolidated financial statements. F-4 MEDISCIENCE TECHNOLOGY CORP. AND SUBSIDIARIES CONSOLIDATED STATEMENTS OF CASH FLOWS YEARS ENDED FEBRUARY 28, 2007 AND 2006
2007 2006 ----------- ----------- CASH FLOWS FROM OPERATING ACTIVITIES Net loss $(1,413,195) $(2,198,668) Adjustments to reconcile net loss to net cash used in operating activities Depreciation 945 600 Amortization 531,208 971,192 Common stock issued for other services 14,880 4,680 (Increase) decrease in assets Prepaid expenses (505) (183) Increase (decrease) in liabilities Accounts payable 6,767 (64,300) Accrued liabilities 436,773 147,714 ----------- ----------- Net cash used in operating activities (423,127) (1,138,965) ----------- ----------- CASH FLOWS FROM INVESTING ACTIVITIES Purchase of equipment -- (2,070) ----------- ----------- CASH FLOWS FROM FINANCING ACTIVITIES Proceeds from issuance of convertible debt 75,000 -- Repayments of officer and other loans -- (31,542) Issuance of common stock for cash 350,000 375,000 ----------- ----------- Net cash provided by financing activities 425,000 343,458 ----------- ----------- NET INCREASE (DECREASE) IN CASH 1,873 (797,577) CASH - BEGINNING OF YEAR 136,635 934,212 ----------- ----------- CASH - END OF YEAR $ 138,508 $ 136,635 =========== =========== SUPPLEMENTAL SCHEDULE OF NON-CASH FINANCING ACTIVITIES: Common stock issued for prepaid lease $ 21,000 $ -- =========== =========== Common stock issued for deferred charges $ 167,520 $ 632,040 =========== =========== Common stock issued for cancellation of accrued expenses $ 28,333 $ 17,167 =========== =========== Common stock issued - anti-dilutive rights $ 7,599 $ 7,155 =========== =========== Discount on debt due to beneficial conversion option $ 75,000 $ -- =========== ===========
The accompanying notes are an integral part of these consolidated financial statements. F-5 MEDISCIENCE TECHNOLOGY CORP. AND SUBSIDIARIES NOTES TO CONSOLIDATED FINANCIAL STATEMENTS FEBRUARY 28, 2007 AND 2006 NOTE 1 - NATURE OF BUSINESS AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES Nature of the Business - ---------------------- The consolidated financial statements include the accounts of Mediscience Technology Corp. ("Mediscience") and its wholly-owned subsidiaries, Laser Diagnostic Instruments, Inc. ("Laser"), Photonics for Women's Oncology, LLC ("Photonics") and Mediphotonics Development, LLC ("Mediphotonics"), and Bioscopix, Inc. ("Bioscopix"), (collectively the "Company"). All significant intercompany transactions and balances have been eliminated in consolidation. Mediphotonics is the only active subsidiary of the Company. The Company operates in one business segment and is principally engaged in the design and development of medical diagnostic instruments that detect cancer in vivo in humans by using light to excite the molecules contained in tissue and measuring the differences in the resulting natural fluorescence between cancerous and normal tissue. Management's Plan - ----------------- The Company is subject but not limited to a number of risks similar to those of other companies at this stage of development, including dependence on key individuals, the development of commercially usable products and processes, competition from substitute products or alternative processes, the impact of research and product development activity, competitors of the Company, many of whom have greater financial or other resources than those of the Company, the uncertainties related to technological improvements and advances, the ability to obtain adequate additional financing necessary to fund continuing operations and product development and the uncertainties of future profitability. The Company expects to incur substantial additional costs before beginning to generate income from product sales, including costs related to ongoing research and development activities, preclinical studies and regulatory compliance. Substantial additional financing is needed by the Company. The Company has no revenues, incurred significant losses from operations, has an accumulated deficit and a highly leveraged position that raises substantial doubt about the Company's ability to continue as a going concern. The consolidated financial statements do not include any adjustments relating to recoverability and classification of recorded asset amounts or the amount and classification of liabilities that might be necessary should the Company be unable to continue as a going concern. The Company expects to incur substantial expenditures to further the development and commercialization of its products. To achieve this, management will seek to enter into an agreement with a consulting firm to be an advisor and explore options for the Company to commercialize its technology, will seek additional financing through private placements or other financing alternatives, and might also seek to sell the Company or its technology. There can be no assurance that continued financings will be available to the Company or that, if available, the amounts will be sufficient or that the terms will be acceptable to the Company. Use of Estimates The preparation of financial statements in conformity with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those estimates. Equipment Equipment is stated at cost. Depreciation is computed using the straight-line method over an estimated useful life of five years. Depreciation expense was $945 and $600 in 2007 and 2006, respectively. F-6 MEDISCIENCE TECHNOLOGY CORP. AND SUBSIDIARIES NOTES TO CONSOLIDATED FINANCIAL STATEMENTS FEBRUARY 28, 2007 AND 2006 NOTE 1 - NATURE OF BUSINESS AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONT.) Income Taxes - ------------ The Company accounts for income taxes under Statement of Financial Accounting Standards ("SFAS") No. 109, Accounting for Income Taxes, which requires an asset and liability approach to financial accounting and reporting for income taxes. Deferred income tax assets and liabilities are computed annually for temporary differences between the financial statement and tax bases of assets and liabilities that will result in taxable or deductible amounts in the future based on enacted tax laws and rates applicable to the periods in which the differences are expected to affect taxable income. Valuation allowances are established when necessary to reduce deferred tax assets to the amount expected to be realized. Income tax expense is the tax payable or refundable for the period plus or minus the change during the period in deferred tax assets and liabilities. Research and Development - ------------------------ Research and development costs are charged to operations when incurred. The amounts charged to expense were $260,137 and $320,953 in 2007 and 2006, respectively. Loss per Common Share - --------------------- In accordance with SFAS No. 128, "Earnings per Share," basic and diluted net loss per share is computed using net loss divided by the weighted average number of shares of common stock outstanding for the period presented. Because the Company reported a net loss for each of the years ended February 28, 2007 and 2006, common stock equivalents consisting of options and warrants were anti-dilutive; therefore, the basic and diluted net loss per share for each of these periods were the same. Accounting for Stock-Based Compensation - --------------------------------------- The Company accounts for stock-based compensation in accordance with SFAS No. 123R, Share-Based Payment, which addresses the accounting for share-based payment transactions in which an enterprise receives employee services in exchange for (a) equity instruments of the enterprise or (b) liabilities that are based on the fair value of the enterprise's equity instruments or that may be settled by the issuance of such equity instruments. SFAS No. 123R eliminates the ability to account for share-based compensation transactions using the intrinsic value method under APB Opinion No. 25, and requires instead that such transactions be accounted for using a fair-value-based method. The Company's assessment of the estimated stock-based compensation expense is affected by the Company's stock price as well as assumptions regarding a number of complex variables and the related tax impact. These variables include, but are not limited to, the Company's stock price, volatility, and employee stock option exercise behaviors and the related tax impact. The Company will recognize stock-based compensation expense on all awards on a straight-line basis over the requisite service period using the modified prospective method. The adoption of SFAS No. 123R effective March 1, 2006 had no effect on the Company's results of operations since there were no nonvested options at March 1, 2006 and there were no employee stock options issued during the current year ended February 28, 2007. Future changes to various assumptions used to determine the fair value of awards issued or the amount and type of equity awards granted create uncertainty as to whether future stock-based compensation expense will be similar to the historical SFAS No. 123 pro forma expense. During the prior year ended February 28, 2006, compensation cost for the Company's employee stock option plan had been determined based on the intrinsic fair value of the Company's common stock at the dates of awards as permitted under SFAS No. 123. If the Company had used the fair value method for 2006, the net loss and net loss per common share would have been increased to the pro forma amounts indicated below. In 2006, the fair value amounts were estimated using the Black-Scholes options pricing model with the following assumptions: no dividend yield, expected volatility of 60%, risk-free interest rate of 4.5% and expected option life of five years. During the year ended February 28, 2006, an option was granted to purchase 300,000 shares of $1.00 per share. 2006 ------------ Net loss: As reported $ 2,198,668 Pro forma $ 2,210,668 Net loss per common share basic and diluted: As reported $ (0.037) Pro forma $ (0.038) F-7 MEDISCIENCE TECHNOLOGY CORP. AND SUBSIDIARIES NOTES TO CONSOLIDATED FINANCIAL STATEMENTS FEBRUARY 28, 2007 AND 2006 NOTE 1 - NATURE OF BUSINESS AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONT.) Concentration of Credit Risk Involving Cash - ------------------------------------------- The Company may have deposits with major financial institutions which exceed Federal Deposit Insurance limits during the year. These financial institutions have strong credit ratings, and management believes the credit risk related to these deposits is minimal. Recently Issued Accounting Pronouncements - ----------------------------------------- In June, 2006, the Financial Accounting Standards Board ("FASB") issued Interpretation No. 48 ("FIN 48"), Accounting for Uncertainty in Income Taxes. FIN 48 prescribes detailed guidance for the financial statement recognition, measurement and disclosure of uncertain tax positions recognized in an enterprise's financial statements in accordance with FASB Statement No. 109, Accounting for Income Taxes. Tax positions must meet a more-likely-than-not-recognition threshold at the effective date to be recognized upon the adoption of Fin 48 and in subsequent periods. FIN 48 will be effective for fiscal years beginning after December 15, 2006, and will become effective for us beginning with the first quarter of 2007, and the provisions of FIN 48 will be applied to all tax positions under Statement No. 109 upon initial adoption. The cumulative effect of applying the provisions of this interpretation will be reported as an adjustment to the opening balance of retained earnings for that fiscal year. The Company is currently evaluating the potential impact of FIN 48 on its consolidated financial statements. In September, 2006, the SEC issued Staff Accounting Bulletin No. 108 ("SAB No. 108"). SAB No. 108 addresses the process and diversity in practice of quantifying financial statement misstatements resulting in the potential build up of improper amounts on the balance sheet. The Company was required to adopt the provisions of SAB No. 108 in fiscal 2007. The adoption of SAB No. 108 did not have a material impact on its consolidated financial statements. In September 2006, the FASB issued SFAS No. 157, Fair Value Measurements. SFAS No. 157 establishes a framework for measuring fair value and expands disclosures about fair value measurements. The changes to current practice resulting from the application of this Statement relate to the definition of fair value, the methods used to measure fair value, and the expanded disclosures about fair value measurements. The Statement is effective for fiscal years beginning after November 15, 2007 and will become effective beginning with the first quarter of 2008. The Company has not yet determined the impact of the adoption of SFAS No. 157 on its financial statements and footnote disclosures. In February, 2007, the FASB issued SFAS No. 159, The Fair Value Option for Financial Assets and Financial Liabilities. This Statement permits entities to choose to measure many financial instruments and certain other items at fair value that are not currently required to be measured at fair value. The objective is to improve financial reporting by providing entities with the opportunity to mitigate volatility in reported earnings caused by measuring related assets and liabilities differently without having to apply complex hedge accounting provisions. This statement also establishes presentation and disclosure requirements designed to facilitate comparisons between entities that choose different measurement attributes for similar types of assets and liabilities. This Statement is effective for financial statements issued for fiscal years beginning after November 15, 2007 and will become effective for us beginning with the first quarter of 2008. The Company has not yet determined the impact of the adoption of SFAS No. 159 on its financial statements and footnote disclosures. NOTE 2 - RELATED PARTY TRANSACTIONS Legal services rendered by Mr. Peter Katevatis amounted to $50,000 for each of the two years ended February 28, 2007 and 2006. These amounts are recorded in general and administrative expense. As part of Mr. Katevatis' employment agreement, the Company pays property taxes and certain operating expenses on the home of Mr. Katevatis in lieu of rent, since the Company's operations are located in Mr. Katevatis' home. Expenses recognized were $20,897 and $21,378 in 2007 and 2006, respectively, and are recorded in general and administrative expense. See Note 7 for details regarding the Company's consulting agreement with one of its principal stockholders and Note 4 for related party loans and accrued liabilities. F-8 MEDISCIENCE TECHNOLOGY CORP. AND SUBSIDIARIES NOTES TO CONSOLIDATED FINANCIAL STATEMENTS FEBRUARY 28, 2007 AND 2006 NOTE 3 - DEFERRED CHARGES In fiscal 2007 and 2006, the Company issued 1,072,000 and 1,366,000 fully vested restricted shares of its common stock at fair market value to four different consulting groups in exchange for a variety of services to be rendered, over a period of 12 - 36 and 6 - 24 months, respectively, for matters such as corporate management, marketing opportunities, product development and research, corporate funding, investor relations and FDA clinical trials. These costs have been capitalized and will be recognized ratably over the terms of the agreements. Expected future amortization of deferred charges is as follows: Years Ending ----------------- February 29, 2008 $ 472,959 February 28, 2009 177,488 February 28, 2010 100,547 ---------- $ 750,994 ========== NOTE 4 - ACCRUED LIABILITIES Accrued liabilities consist of the following: -------------------------------------------------------------- 2007 2006 -------------------------------------------------------------- Legal and professional fees $ 227,381 $ 203,382 -------------------------------------------------------------- Consulting and university fees 1,438,415 1,276,414 -------------------------------------------------------------- Salaries and wages 1,764,667 1,542,667 -------------------------------------------------------------- Other 101,435 100,995 -------------------------------------------------------------- $ 3,531,898 $3,123,458 ============================================================== Accrued legal and professional fees include services rendered by Mr. Peter Katevatis. The amount of the accrual was $75,958 and $55,958 as of February 28, 2007 and 2006, respectively (Note 2). Accrued consulting and university fees include costs owed to Dr. Robert R. Alfano, a principal stockholder and chairman of the Company's Scientific Advisory Board (Note 7), with respect to his consulting agreement of $1,394,818 and $1,232,818 as of February 28, 2007 and 2006, respectively. Accrued expense reimbursements of $92,235 and $80,795 were due to Dr. Alfano at February 28, 2007 and 2006. Accrued salaries and wages include amounts due to Mr. Katevatis of $1,689,667 and $1,489,667, and $15,000 and $10,500 to Mr. Frank D. Benick, Chief Financial Officer, and $60,000 and $42,500 due to Mr. Englehart, former President, as of February 28, 2007 and 2006, respectively. NOTE 5 - CONVERTIBLE DEBT On January 10, 2007, the Company commenced a Private Placement Offering for $2,000,000 of 12% convertible promissory notes ("the Notes") in amounts of not less than $25,000. The Notes shall be due and payable, together with accrued and unpaid interest on the earlier of April 15, 2008 or three months after the completion of the initial public offering ("the IPO") of the shares of Bioscopix. Holders of the Notes may convert the notes into (i) cash in the amount of the principal and accrued and unpaid interest due and a warrant exercisable until April 15, 2009 to purchase shares of Bioscopix in an amount equal to 50% of the principal of the Notes at an exercise price of 120% of the five day volume weighted average price preceding the effective date of the IPO of Bioscopix or (ii) shares of Bioscopix at a price equal to 50% of the IPO price of the Bioscopix shares of common stock in an amount equal to the principal and accrued and unpaid interest due on the Notes. In accordance with EITF 00-27 under option (ii), the carrying value of the Notes was reduced by the intrinsic value of the beneficial conversion option resulting in a carrying value of $0. As of February 28, 2007, $75,000 of Notes have been issued with related discount of $75,000. The Notes will be accreted to their maturity value over the term of the Notes. F-9 MEDISCIENCE TECHNOLOGY CORP. AND SUBSIDIARIES NOTES TO CONSOLIDATED FINANCIAL STATEMENTS FEBRUARY 28, 2007 AND 2006 NOTE 6 - INCOME TAXES There is no income tax benefit for operating losses for the years ended February 28, 2007 and 2006 due to the following: Current tax benefit - the operating losses cannot be carried back to earlier years. Deferred tax benefit - the deferred tax assets were offset by a valuation allowance required by FASB Statement 109, "Accounting for Income Taxes." The valuation allowance is necessary because, according to criteria established by FASB Statement 109, it is more likely than not that the deferred tax asset will not be realized through future taxable income. The components of the net deferred income tax asset and liability as of February 28, 2007 and 2006 are as follows: ----------- ----------- Deferred income tax asset: Net operating loss carryforward $ 6,384,718 $ 5,933,439 Valuation allowance (6,384,718) (5,933,439) ----------- ----------- Deferred income tax liability -- -- ----------- ----------- $ -- $ -- =========== =========== As of February 28, 2007 and 2006, the Company has valuation allowances of $6,384,718 and $5,933,439, respectively, which relates to federal and state net operating loss carryforwards. The Company evaluates a variety of factors in determining the amount of the valuation allowance, including the Company's earnings history, the number of years the Company's operating losses can be carried forward, the existence of taxable temporary differences, and near-term earnings expectations. Future reversal of the valuation allowance will be recognized either when the benefit is realized or when it has been determined that it is more likely than not that the benefit will be realized through future earnings. As of February 28, 2007 and 2006, the Company has net operating loss carryforwards of approximately $17,471,000 and $16,391,000, respectively for federal purposes and $7,482,000 and $6,069,000, respectively, for state purposes, which may be used to reduce future income subject to income taxes. The net operating losses are scheduled to expire in the following years: Federal State Total ----------- ----------- ----------- 2008 370,000 -- 370,000 2009 854,000 -- 854,000 2010 615,000 129,000 744,000 2011 1,136,000 315,000 1,451,000 2012 1,556,000 216,000 1,772,000 2013 2,636,000 850,000 3,486,000 2014 1,128,000 2,361,000 3,489,000 2015 -- 2,198,000 2,198,000 2019(*) 808,000 1,413,000 2,221,000 2020(*) 943,000 -- 943,000 2021(*) 298,000 -- 298,000 2022(*) 316,000 -- 316,000 2023(*) 182,000 -- 182,000 2024(*) 786,000 -- 786,000 2025(*) 2,284,000 -- 2,284,000 2026(*) 2,172,000 -- 2,172,000 2027(*) 1,387,000 -- -- ----------- ----------- ----------- Total $17,471,000 $ 7,482,000 $24,953,000 =========== =========== =========== (*) Under the Taxpayer Relief Act of 1997, the carryforward period of net operating losses arising after May 1, 1998 was extended from 15 to 20 years. F-10 MEDISCIENCE TECHNOLOGY CORP. AND SUBSIDIARIES NOTES TO CONSOLIDATED FINANCIAL STATEMENTS FEBRUARY 28, 2007 AND 2006 NOTE 7- COMMITMENTS AND CONTINGENCIES Dr. Robert R. Alfano - -------------------- The Company has a consulting agreement (the "Agreement") through March 2007 with Dr. Robert R. Alfano, a principal stockholder of the Company and Chairman of its Scientific Advisory Board. Pursuant to the terms of the Agreement, Dr. Alfano is paid a consulting fee of not less than $150,000 per annum in exchange for services to be rendered for approximately fifty days per annum in connection with the company's medical photonics business. The Agreement further provides that Dr. Alfano is to be paid a bonus and fringe benefits in accordance with policies and formulas provided to key executives of the Company. It is not the intention of management to renew with this agreement. In connection with the acquisition of patent rights to its cancer detection technology, the Company assumed an obligation to pay to Dr. Alfano's daughter a royalty of one percent of the gross sales derived from any equipment made, leased or sold which utilizes the concepts described in the Company's cancer detection patent. Since there has been no activity, no amounts have been paid during the two years ended February 28, 2007. Other Royalties - --------------- The Company obtained worldwide licensing rights for patents from Yale University and has agreed to pay royalties based on net sales of all products generated from the patents and fifty percent of any income received from sublicensing of the patents. The Company has not recorded any revenues since the inception of this agreement and therefore has not recorded or paid any royalties during the two years ended February 28, 2007. Employment Agreements - --------------------- Mr. Peter Katevatis, the Chief Executive Officer, Chairman and a stockholder of the Company, has an employment agreement. The agreement was renewed on March 5, 2007 which increased his salary from $200,000 to $250,000 per year. The agreement also provides for a bonus and fringe benefits in accordance with policies and formulas mutually agreed upon by Mr. Katevatis and the Board of Directors. The contract expires March 5, 2015. On November 15, 2005, the Company entered into a two year employment agreement with Frank D. Benick as Chief Financial Officer. Mr. Benick will be paid a monthly salary of $3,000 per month for the first two months, then increasing to $4,000 per month for the remaining term of the agreement and received an option to purchase 300,000 shares of common stock at $1.00 per share (see Note 1 for pro forma disclosure). NOTE 8 - STOCKHOLDERS' DEFICIT Preferred Stock - --------------- The Company is authorized to issue 50,000 shares of preferred stock, $.01 par value per share, which may be issued from time-to-time in one or more series, the terms of which may be designated by the Board of Directors without further action by stockholders. Any preferred stock issued will have preferences with respect to dividends, liquidation and other rights, but will not have preemptive rights. Holders of series A preferred stock are entitled to a preference of $10 per share before any payment is made to holders of common stock in liquidation of the assets of the Company. Additionally, holders of series A preferred stock have no redemption or dividend rights and vote only with respect to corporate matters affecting their respective rights, preferences or limitations, but do not vote for the election of directors or on general corporate matters. Private Placements - ------------------ Common Stock ------------ During fiscal 2006, the Company issued 750,000 shares of common stock at a price of $.50 per share for $375,000. During fiscal 2007, the Company issued 2,332,665 shares of common stock at a price of $.15 per share for $350,000. F-11 MEDISCIENCE TECHNOLOGY CORP. AND SUBSIDIARIES NOTES TO CONSOLIDATED FINANCIAL STATEMENTS FEBRUARY 28, 2007 AND 2006 NOTE 8 - STOCKHOLDERS' DEFICIT (CONT.) Common Stock Issued for Services - -------------------------------- During November 2005, the Company issued 23,400 shares of its common stock at a fair market value of $.20 per share to a consultant for research and development services. This non-cash expense was recorded as general and administrative expense in the consolidated statement of operations. During April 2006, the Company issued 93,000 shares of its common stock at a fair market value of $.16 per share to a consultant for research and development services. This non-cash expense was recorded as general and administrative expense in the consolidated statement of operations. Common Stock Issued for Future Services - --------------------------------------- During March 2005, the Company issued 711,000 restricted shares of its common stock at a fair market value of $.64 and $.68 per share to two consulting groups in exchange for medical and financial consulting services to be rendered over a one year period. During April 2005, the Company issued 100,000 restricted shares of its common stock at a fair market value of $.55 per share to a consulting firm in exchange for public and investor relations consulting services to be rendered over a six month period. During November 2005, the Company issued 100,000 restricted shares of its common stock at a fair market value of $.20 per share to a consulting firm in exchange for public and investor relations consulting services to be rendered over a two year period. During December 2005, the Company issued 375,000 restricted shares of its common stock at an average fair market value approximating $.18 per share to a consultant in exchange for medical consulting services to be rendered over a two year period. During February 2006, the Company issued 80,000 restricted shares of its common stock at a fair market value of $.20 per share to a consultant in exchange for medical consulting services to be rendered over a twenty-two month period. During March, 2006, the Company issued 500,000 restricted shares of its common stock at a fair market value of $0.16 per share to a consultant in exchange for consulting services to be rendered over a three year period. During March, 2006 and May, 2006, the Company issued a total of 372,000 restricted shares of its common stock at a fair market value of $0.16 per share to a consultant in exchange for consulting services to be rendered over a twelve month period. During February, 2007, the Company issued 200,000 restricted shares of its common stock at a fair market value of $0.14 per share to a consultant in exchange for consulting services to be rendered over a twelve month period. Common Stock Issued for Prepaid Lease - ------------------------------------- On February 22, 2007, the Company issued 150,000 shares at a fair market value of $.14 per share for a two year lease on office space in California. 2003 Consultants Stock Plan - --------------------------- The Board of Directors previously adopted, subject to stockholder approval, a 2003 Consultants Stock Plan ("Consultants Plan"). The Consultants Plan was subsequently approved by the stockholders on February 17, 2004. The aggregate number of shares that may be issued under the options shall not exceed 7 million. No options were issued prior to stockholder approval and no options were outstanding under this plan as of February 28, 2007 and 2006. F-12 MEDISCIENCE TECHNOLOGY CORP. AND SUBSIDIARIES NOTES TO CONSOLIDATED FINANCIAL STATEMENTS FEBRUARY 28, 2007 AND 2006 NOTE 8 - STOCKHOLDERS' DEFICIT (CONT.) 1999 Incentive Stock Option Plan - -------------------------------- The Board of Directors previously adopted, subject to stockholder approval, a 1999 Incentive Stock Option Plan (the "Plan") for officers and employees of the Company. The stockholders subsequently approved the Plan on February 17, 2004. Accordingly awards issued under the Plan prior to February 17, 2004 were deemed not to be granted until that date. The aggregate number of shares that may be issued under the options shall not exceed 3 million. During November 2005, Mr. Benick was granted options to purchase up to 300,000 shares of the Company's common stock at an option price of $1.00 per share. The option has an expiration date of November 15, 2010. Activity related to stock options during the two years ended February 28, 2007 is as follows: Shares Range Price ---------- ------------- ---------- Outstanding, February 28, 2005 2,400,000 $ .25 - $2.00 $ 1.04 Granted 300,000 $1.00 $ 1.00 ---------- Outstanding, February 28, 2006 2,700,000 $ .25 - $2.00 $ 1.04 Granted -- -- $ -- Forfeited (2,000,000) $ .25 - $1.00 ---------- Outstanding, February 28, 2007 700,000 $1.00 - $2.00 $ 1.50 ========== Common Stock Subscribed In February 2005, the Company received $250,000 in common stock subscriptions for 500,000 shares issued in March 2005. Stock Warrants Stock warrant activity during the two year period ended February 28, 2007 was as follows: --------- ------------- Outstanding, February 28, 2005 3,350,000 $1.00 - $3.00 Granted 1,250,000 $ 1.00 Exercised -- Forfeited -- --------- Outstanding, February 28, 2006 4,600,000 $ .25 - $3.00 Granted 1,999,332 $ 0.25 Exercised -- -- Forfeited -- -- --------- ------------- Outstanding, February 28, 2007 6,599,332 $0.25 - $3.00 ========= ============= For stock that had been previously subscribed, in connection with its private placement offering during 2005, the Company granted warrants to purchase 500,000 shares of common stock at $1.00 per share. The warrants expire in August 2007. In connection with its private placement offering in 2005 and its extension into fiscal 2006, the Company granted warrants to purchase 750,000 shares of common stock at $1.00 per share. The warrants expired in August 2007. In connection with its private placement offers in 2005 and its extension into fiscal 2007, the Company granted warrants to purchase 1,999,332 shares of common stock at $1.00 per share. The warrants expire in August 2008. F-13 MEDISCIENCE TECHNOLOGY CORP. AND SUBSIDIARIES NOTES TO CONSOLIDATED FINANCIAL STATEMENTS FEBRUARY 28, 2007 AND 2006 NOTE 8 - STOCKHOLDERS' DEFICIT (CONT.) Anti-Dilution Rights The Company and Mr. Peter Katevatis have an anti-dilution rights agreement which provides that Mr. Katevatis' ownership interest would at all times represent 17% of the issued and outstanding shares of the Company. The anti-dilution rights are exercisable at Mr. Katevatis' sole discretion. During the years ended February 28, 2007 and 2006, Mr. Katevatis exercised his right and requested the Company issue 641,478 and 579,173 common shares respectively. As of February 28, 2007, the Company is obligated to issue an additional 8,204 shares to Mr. Katevatis in connection with the anti-dilution rights. In connection with the issuance of these shares, the Company has capitalized only the stock's par value from paid in capital because of the Company's accumulated deficit position. Anti-Dilution Rights The Company and Dr. Robert Alfano have an anti-dilution rights agreement which provides that Dr. Alfano's ownership interest would at all times represent 4% of the issued and outstanding shares of the Company. The anti-dilution rights are exercisable at Dr. Alfano's sole discretion. During the years ended February 28, 2006 and 2005, Dr. Alfano exercised his right and requested the Company issue 118,572 and 136,276 common shares, respectively. As of February 28, 2007, the Company is obligated to issue an additional 14,001 shares to Dr. Alfano in connection with the anti-dilution rights. In connection with the issuance of these shares, the Company has capitalized only the stock's par value from paid in capital because of the Company's accumulated deficit position. Debt Conversion On March 8, 2005, the Trust converted $3,667 of accrued interest into 7,334 shares of the Company's common stock. On November 8, 2005, the Company converted $13,500 of accrued professional fees for 67,500 shares of the Company's common stock. On November 15, 2006, the Company converted $28,333 of accrued salary for 166,666 shares of the Company's common stock. F-14 SIGNATURES In accordance with Section 13 or 15(d) of the Exchange Act, the registrant caused this report to be signed on its behalf by the undersigned, thereunto duly authorized. MEDISCIENCE TECHNOLOGY CORP. Date: June 13, 2007 By: /s/ Peter Katevatis ----------------------------------------------- Peter Katevatis Esq. Chairman of the Board, Treasurer and Chief Executive Officer In accordance with the Exchange Act, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated. Date: June 13, 2007 By: /s/ Peter Katevatis ----------------------------------------------- Peter Katevatis Esq. Chairman of the Board, Treasurer and Chief Executive Officer (Principal Executive Officer) Date: June 13, 2007 By: /s/ Frank D. Benick ----------------------------------------------- Frank D. Benick, CPA, CVA Chief Financial Officer (Principal Financial and Accounting Officer) Date: June 13, 2007 By: /s/ John M. Kennedy ----------------------------------------------- John M. Kennedy Director, Vice President and Secretary Date: June 13, 2007 By: /s/ William Armstrong ----------------------------------------------- William Armstrong Director Date: June 13, 2007 By: /s/ Michael N. Kouvatas ----------------------------------------------- Michael N. Kouvatas Director MEDISCIENCE TECHNOLOGY CORP. Form 10-KSB For the fiscal year ended February 28, 2007 Exhibit Index 31.1 Certification of the Chief Executive Officer required by Rule 13a-14(a) or Rule 15d-14(a) ** 31.2 Certification of the Chief Financial Officer required by Rule 13a-14(a) or Rule 15d-14(a) ** 32 Certification of the Chief Executive Officer and the Chief Financial Officer required by Rule 13a-14(b) or Rule 15d-14(b) and 18 U.S.C. 1350 ** * Previously filed ** Filed herewith
EX-31.1 2 ex31-1.txt Exhibit 31.1 CERTIFICATIONS I, Peter Katevatis, Chief Executive Officer of the registrant, certify that: 1. I have reviewed this Annual Report on Form 10-KSB of Mediscience Technology Corp.; 2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report; 3. Based on my knowledge, the financial statements, and other financial information included in this annual report, fairly present in all material respects the financial condition, results of operations and cash flows of the small business issuer as of, and for, the periods presented in this report; 4. The small business issuer's other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) for the small business issuer and have: (a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the small business issuer, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared; (b) [this paragraph has been omitted] (c) Evaluated the effectiveness of the small business issuer's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and (d) Disclosed in this report any change in the small business issuer's internal control over financial reporting that occurred during the small business issuer's most recent fiscal quarter (the small business issuer's fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the small business issuer's internal control over financial reporting; and 5. The small business issuer's other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the small business issuer's auditors and the audit committee of the small business issuer's board of directors (or persons performing the equivalent functions): (a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the small business issuer's ability to record, process, summarize and report financial information; and (b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the small business issuer's internal control over financial reporting. Date: June 13, 2007 By: /s/ Peter Katevatis ------------------------------------- Peter Katevatis Chief Executive Officer EX-31.2 3 ex31-2.txt Exhibit 31.2 CERTIFICATIONS I, Frank D. Benick, Chief Financial Officer of the registrant, certify that: 1. I have reviewed this Annual Report on Form 10-KSB of Mediscience Technology Corp.; 2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report; 3. Based on my knowledge, the financial statements, and other financial information included in this annual report, fairly present in all material respects the financial condition, results of operations and cash flows of the small business issuer as of, and for, the periods presented in this report; 4. The small business issuer's other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) for the small business issuer and have: (a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the small business issuer, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared; (b) [this paragraph has been omitted] (c) Evaluated the effectiveness of the small business issuer's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and (d) Disclosed in this report any change in the small business issuer's internal control over financial reporting that occurred during the small business issuer's most recent fiscal quarter (the small business issuer's fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the small business issuer's internal control over financial reporting; and 5. The small business issuer's other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the small business issuer's auditors and the audit committee of the small business issuer's board of directors (or persons performing the equivalent functions): (a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the small business issuer's ability to record, process, summarize and report financial information; and (b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the small business issuer's internal control over financial reporting. Date: June 13, 2007 By: /s/ Frank D. Benick --------------------------------------- Frank D. Benick Chief Financial Officer EX-32 4 ex32.txt Exhibit 32 PURSUANT TO 18 U.S.C. 1350 In connection with the accompanying Annual Report of Mediscience Technology Corp. (the "Company") on Form 10-KSB for the fiscal year ended February 28, 2007 (the "Report"), each of the undersigned officers of the Company, hereby certify that to such officer's knowledge: (1) The Report fully complies with the requirements of Section 15(d) of the Securities Exchange Act of 1934 (15 U.S.C. ss.78o(d)); and (2) The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company. Date: June 13, 2007 By: /s/ Peter Katevatis ------------------------------------- Peter Katevatis Chief Executive Officer Date: June 13, 2007 By: /s/ Frank D. Benick ------------------------------------- Frank D. Benick Chief Financial Officer The above certification is furnished solely pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 (18 U.S.C. ss.1350) and is not being filed as part of the Form 10-KSB or as a separate disclosure document.
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