Exhibit 107

Calculation of Filing Fee Tables

Form S-3

(Form Type)

Eli Lilly and Company

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial Effective Date

Filing Fee Previously Paid In Connection with Unsold Securities to be Carried Forward

Newly Registered Securities

Fees to Be Paid

Equity

Common Stock(1)

Rule 456(b) and Rule 457(r) (2)

(3)(4)

(3)(4)

(3)(4)(5)

(2)

(2)

Equity

Preferred Stock(1)

Rule 456(b) and Rule 457(r) (2)

(3)(4)

(3)(4)

(3)(4)(5)

(2)

(2)

Equity

Depositary Shares representing Preferred Stock(1)

Rule 456(b) and Rule 457(r) (2)

(3)(4)

(3)(4)

(3)(4)(5)

(2)

(2)

Debt

Debt Securities(1)

Rule 456(b) and Rule 457(r) (2)

(3)(4)

(3)(4)

(3)(4)(5)

(2)

(2)

Other

Warrants(1)

Rule 456(b) and Rule 457(r) (2)

(3)(4)

(3)(4)

(3)(4)(5)

(2)

(2)

Other

Stock Purchase Contracts(1)

Rule 456(b) and Rule 457(r) (2)

(3)(4)

(3)(4)

(3)(4)(5)

(2)

(2)

Other

Stock Purchase Units(1)

Rule 456(b) and Rule 457(r) (2)

(3)(4)

(3)(4)

(3)(4)(5)

(2)

(2)

Fees Previously Paid

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Carry Forward Securities

Carry Forward Securities

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Total Offering Amounts

N/A

N/A

Total Fees Previously Paid

N/A

Total Fee Offsets

N/A

Net Fee Due

N/A

(1) Separate consideration may or may not be received for securities that are issuable on exercise, conversion, settlement or exchange of other securities.

(2) In accordance with Rules 456(b) and 457(r) under the Securities Act of 1933, as amended, Eli Lilly and Company (the “Registrant”) is deferring payment of all of the registration fee. Registration fees will be paid subsequently on a “pay as you go” basis. The Registrant will calculate the registration fee applicable to an offer of securities pursuant to this Registration Statement based on the fee payment rate in effect on the date of such fee payment.

(3) An indeterminate aggregate initial offering price and number or amount of the securities of each identified class is being registered as may from time to time be issued at indeterminate prices, including securities that may be issued upon exercise, conversion, settlement or exchange of, any securities offered hereunder.

(4) Not specified as to each class of securities to be registered, pursuant to General Instruction II.E. of Form S-3.

(5) Exclusive of accrued interest and accumulated dividends, if any.