144 0000316011 XXXXXXXX LIVE 0000059478 ELI LILLY AND COMPANY 001-06351 LILLY CORPORATE CTR DROP CODE 1094 INDIANAPOLIS IN 46285 317-276-2000 LILLY ENDOWMENT, INC. Shareholder Common Stock J.P. Morgan Securities LLC

383 Madison Avenue New York NY 10179

300000 347247000 941357065 10/07/2026 NYSE, NASDAQ Common Stock 02/10/1948 Gift J.K. Lilly Sr. Trust Y 01/21/1937 38400000 N/A N Lilly Endowment Inc.

2801 North Meridian Street Indianapolis IN 46208

Eli Lilly and Company Common Stock 07/07/2026 80 99200 Lilly Endowment Inc.

2801 North Meridian Street Indianapolis IN 46208

Eli Lilly and Company Common Stock 07/08/2026 7395 9172695.88 Lilly Endowment Inc.

2801 North Meridian Street Indianapolis IN 46208

Eli Lilly and Company Common Stock 08/13/2026 122 151280 Lilly Endowment Inc.

2801 North Meridian Street Indianapolis IN 46208

Eli Lilly and Company Common Stock 08/19/2026 302403 385708676.04 10/07/2026 /s/ Peter A. Buck, Vice President for Investments and Grants Administration