Consolidated Statements of Operations - USD ($) shares in Millions, $ in Millions	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Income Statement [Abstract]
Revenue	$ 65,179	$ 45,043	$ 34,124
Costs, expenses, and other:
Cost of sales	11,052	8,418	7,082
Research and development	13,337	10,991	9,313
Marketing, selling, and administrative	11,094	8,594	7,404
Acquired in-process research and development	2,910	3,280	3,800
Asset impairment, restructuring, and other special charges	484	861	68
Other—net, (income) expense	571	219	(97)
Costs, expenses, and other	39,448	32,363	27,570
Income before income taxes	25,731	12,680	6,554
Income taxes	5,091	2,090	1,314
Net income	$ 20,640	$ 10,590	$ 5,240
Earnings per share:
Basic (in dollars per share)	$ 23.00	$ 11.76	$ 5.82
Diluted (in dollars per share)	$ 22.95	$ 11.71	$ 5.80
Shares used in calculation of earnings per share:
Basic (in shares)	897.3	900.6	900.2
Diluted (in shares)	899.3	904.1	903.3