Revenue - Schedule of Revenue Recognized (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Disaggregation of Revenue [Line Items]
Revenue	$ 45,042.7	$ 34,124.1	$ 28,541.4
Net product revenue
Disaggregation of Revenue [Line Items]
Revenue	40,747.9	28,813.9	25,462.8
Collaboration and other revenue
Disaggregation of Revenue [Line Items]
Revenue	$ 4,294.8	$ 5,310.2	$ 3,078.6