Segment Information (Details) $ in Millions	12 Months Ended
	Dec. 31, 2024 USD ($) segment	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)
Segment Reporting [Abstract]
Number of reportable segments | segment	1
Financial Information Regularly Reviewed by the CODM
Revenue	$ 45,042.7	$ 34,124.1	$ 28,541.4
Less:
Cost of sales	8,418.3	7,082.2	6,629.8
Research and development	10,990.6	9,313.4	7,190.8
Marketing, selling, and administrative	8,593.8	7,403.1	6,440.4
Acquired in-process research and development	3,280.4	3,799.8	908.5
Net income	10,590.0	5,240.4	6,244.8
Additional Segment Information
Interest income	175.2	173.6	62.8
Interest expense	780.6	485.9	331.6
Depreciation and amortization	1,766.6	1,527.3	1,522.5
Income taxes	2,090.4	1,314.2	561.6
Total assets	78,714.9	64,006.3
Reportable Segment
Financial Information Regularly Reviewed by the CODM
Revenue	45,042.7	34,124.1	28,541.4
Less:
Cost of sales	8,418.3	7,082.2	6,629.8
Marketing, selling, and administrative	8,593.8	7,403.1	6,440.4
Acquired in-process research and development	3,280.4	3,799.8	908.5
Other segment items	3,169.6	1,285.2	1,127.1
Net income	10,590.0	5,240.4	6,244.8
Additional Segment Information
Interest income	175.2	173.6	62.8
Interest expense	780.6	485.9	331.6
Depreciation and amortization	1,766.6	1,527.3	1,522.5
Asset impairment, restructuring, and other special charges	860.6	67.7	244.6
Earnings (loss) in equity method investments	89.8	(10.1)	(138.0)
Income taxes	2,090.4	1,314.2	561.6
Expenditures for long-lived assets	5,560.8	3,830.2	2,289.2
Total assets	78,714.9	64,006.3
Equity method investments	1,142.7	962.3
Early-stage | Reportable Segment
Less:
Research and development	3,916.9	3,092.5	2,406.6
Late-stage | Reportable Segment
Less:
Research and development	$ 7,073.7	$ 6,220.9	$ 4,784.2