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Revenue (Summary of Revenue Recognized) (Details) - USD ($)
$ in Millions
3 Months Ended 12 Months Ended
Dec. 31, 2019
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Disaggregation of Revenue [Line Items]                      
Revenue $ 6,114.0 $ 5,476.6 $ 5,636.7 $ 5,092.2 $ 5,637.6 $ 5,306.9 $ 5,585.0 $ 4,963.8 $ 22,319.5 $ 21,493.3 $ 19,973.8
Net product revenue                      
Disaggregation of Revenue [Line Items]                      
Revenue                 20,377.3 19,866.4 18,776.5
Collaboration and other revenue                      
Disaggregation of Revenue [Line Items]                      
Revenue                 1,942.2 1,626.9 1,197.3
Collaboration and other revenue associated with prior period transfers of intellectual property                      
Disaggregation of Revenue [Line Items]                      
Revenue                 $ 301.5 $ 303.2 $ 144.9