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Consolidated Statements of Operations - USD ($)
shares in Thousands, $ in Millions
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Income Statement [Abstract]      
Revenue $ 22,319.5 $ 21,493.3 $ 19,973.8
Costs, expenses, and other:      
Cost of sales 4,721.2 4,681.7 4,447.7
Research and development 5,595.0 5,051.2 5,096.2
Marketing, selling, and administrative 6,213.8 5,975.1 5,982.4
Acquired in-process research and development (Note 3) 239.6 1,983.9 1,112.6
Asset impairment, restructuring, and other special charges (Note 5) 575.6 266.9 1,331.6
Other—net, (income) expense (Note 18) (291.6) (145.6) (301.5)
Costs, expenses, and other 17,053.6 17,813.2 17,669.0
Income before income taxes 5,265.9 3,680.1 2,304.8
Income taxes (Note 14) 628.0 529.5 2,391.2
Net income (loss) from continuing operations 4,637.9 3,150.6 (86.4)
Net income (loss) from discontinued operations (Note 19) 3,680.5 81.4 (117.7)
Net income (loss) $ 8,318.4 $ 3,232.0 $ (204.1)
Earnings (loss) per share:      
Earnings (loss) from continuing operations - basic (in usd per share) $ 4.98 $ 3.07 $ (0.08)
Earnings (loss) from discontinued operations - basic (in usd per share) 3.95 0.07 (0.11)
Earnings (loss) per share - basic (in usd per share) 8.93 3.14 (0.19)
Earnings (loss) from continuing operations - diluted (in usd per share) 4.96 3.05 (0.08)
Earnings (loss) from discontinued operations - diluted (in usd per share) 3.93 0.08 (0.11)
Earnings (loss) per share - diluted (in usd per share) $ 8.89 $ 3.13 $ (0.19)
Shares used in calculation of earnings (loss) per share:      
Basic (in shares) 931,059 1,027,721 1,052,023
Diluted (in shares) 935,684 1,033,667 1,052,023